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260 related items for PubMed ID: 12361954

  • 1. Protein kinase C delta associates with the interleukin-6 receptor subunit glycoprotein (gp) 130 via Stat3 and enhances Stat3-gp130 interaction.
    Novotny-Diermayr V, Zhang T, Gu L, Cao X.
    J Biol Chem; 2002 Dec 20; 277(51):49134-42. PubMed ID: 12361954
    [Abstract] [Full Text] [Related]

  • 2. TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex.
    Bode JG, Schweigart J, Kehrmann J, Ehlting C, Schaper F, Heinrich PC, Häussinger D.
    J Immunol; 2003 Jul 01; 171(1):257-66. PubMed ID: 12817006
    [Abstract] [Full Text] [Related]

  • 3. Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.
    Schaper F, Gendo C, Eck M, Schmitz J, Grimm C, Anhuf D, Kerr IM, Heinrich PC.
    Biochem J; 1998 Nov 01; 335 ( Pt 3)(Pt 3):557-65. PubMed ID: 9794795
    [Abstract] [Full Text] [Related]

  • 4. Sequential activation of Rac-1, SEK-1/MKK-4, and protein kinase Cdelta is required for interleukin-6-induced STAT3 Ser-727 phosphorylation and transactivation.
    Schuringa JJ, Dekker LV, Vellenga E, Kruijer W.
    J Biol Chem; 2001 Jul 20; 276(29):27709-15. PubMed ID: 11335711
    [Abstract] [Full Text] [Related]

  • 5. The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6.
    Zhang T, Kee WH, Seow KT, Fung W, Cao X.
    Mol Cell Biol; 2000 Oct 20; 20(19):7132-9. PubMed ID: 10982829
    [Abstract] [Full Text] [Related]

  • 6. Modulation of the interleukin-6 receptor subunit glycoprotein 130 complex and its signaling by LMO4 interaction.
    Novotny-Diermayr V, Lin B, Gu L, Cao X.
    J Biol Chem; 2005 Apr 01; 280(13):12747-57. PubMed ID: 15677447
    [Abstract] [Full Text] [Related]

  • 7. The YXXQ motif in gp 130 is crucial for STAT3 phosphorylation at Ser727 through an H7-sensitive kinase pathway.
    Abe K, Hirai M, Mizuno K, Higashi N, Sekimoto T, Miki T, Hirano T, Nakajima K.
    Oncogene; 2001 Jun 14; 20(27):3464-74. PubMed ID: 11429693
    [Abstract] [Full Text] [Related]

  • 8. The carboxyl-terminal domains of gp130-related cytokine receptors are necessary for suppressing embryonic stem cell differentiation. Involvement of STAT3.
    Ernst M, Novak U, Nicholson SE, Layton JE, Dunn AR.
    J Biol Chem; 1999 Apr 02; 274(14):9729-37. PubMed ID: 10092661
    [Abstract] [Full Text] [Related]

  • 9. Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation.
    Hemmann U, Gerhartz C, Heesel B, Sasse J, Kurapkat G, Grötzinger J, Wollmer A, Zhong Z, Darnell JE, Graeve L, Heinrich PC, Horn F.
    J Biol Chem; 1996 May 31; 271(22):12999-3007. PubMed ID: 8662795
    [Abstract] [Full Text] [Related]

  • 10. Analysis of IL-6-mediated growth control of myeloma cells using a gp130 chimeric receptor approach.
    French JD, Tschumper RC, Jelinek DF.
    Leukemia; 2002 Jun 31; 16(6):1189-96. PubMed ID: 12040452
    [Abstract] [Full Text] [Related]

  • 11. Shc mediates IL-6 signaling by interacting with gp130 and Jak2 kinase.
    Giordano V, De Falco G, Chiari R, Quinto I, Pelicci PG, Bartholomew L, Delmastro P, Gadina M, Scala G.
    J Immunol; 1997 May 01; 158(9):4097-103. PubMed ID: 9126968
    [Abstract] [Full Text] [Related]

  • 12. Protein tyrosine phosphatase 2 (SHP-2) moderates signaling by gp130 but is not required for the induction of acute-phase plasma protein genes in hepatic cells.
    Kim H, Hawley TS, Hawley RG, Baumann H.
    Mol Cell Biol; 1998 Mar 01; 18(3):1525-33. PubMed ID: 9488469
    [Abstract] [Full Text] [Related]

  • 13. The carboxyl-terminal region of STAT3 controls gene induction by the mouse haptoglobin promoter.
    Kim H, Baumann H.
    J Biol Chem; 1997 Jun 06; 272(23):14571-9. PubMed ID: 9169415
    [Abstract] [Full Text] [Related]

  • 14. SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130.
    Schmitz J, Weissenbach M, Haan S, Heinrich PC, Schaper F.
    J Biol Chem; 2000 Apr 28; 275(17):12848-56. PubMed ID: 10777583
    [Abstract] [Full Text] [Related]

  • 15. Activation of the signal transducer gp130 by interleukin-11 and interleukin-6 is mediated by similar molecular interactions.
    Dahmen H, Horsten U, Küster A, Jacques Y, Minvielle S, Kerr IM, Ciliberto G, Paonessa G, Heinrich PC, Müller-Newen G.
    Biochem J; 1998 May 01; 331 ( Pt 3)(Pt 3):695-702. PubMed ID: 9560294
    [Abstract] [Full Text] [Related]

  • 16. Negative regulation of gp130 signalling mediated through tyrosine-757 is not dependent on the recruitment of SHP2.
    Fairlie WD, De Souza D, Nicola NA, Baca M.
    Biochem J; 2003 Jun 01; 372(Pt 2):495-502. PubMed ID: 12593670
    [Abstract] [Full Text] [Related]

  • 17. Signal transduction of IL-6, leukemia-inhibitory factor, and oncostatin M: structural receptor requirements for signal attenuation.
    Anhuf D, Weissenbach M, Schmitz J, Sobota R, Hermanns HM, Radtke S, Linnemann S, Behrmann I, Heinrich PC, Schaper F.
    J Immunol; 2000 Sep 01; 165(5):2535-43. PubMed ID: 10946280
    [Abstract] [Full Text] [Related]

  • 18. Imbalanced gp130-dependent signaling in macrophages alters macrophage colony-stimulating factor responsiveness via regulation of c-fms expression.
    Jenkins BJ, Grail D, Inglese M, Quilici C, Bozinovski S, Wong P, Ernst M.
    Mol Cell Biol; 2004 Feb 01; 24(4):1453-63. PubMed ID: 14749363
    [Abstract] [Full Text] [Related]

  • 19. The designer cytokine hyper-interleukin-6 is a potent activator of STAT3-dependent gene transcription in vivo and in vitro.
    Rakemann T, Niehof M, Kubicka S, Fischer M, Manns MP, Rose-John S, Trautwein C.
    J Biol Chem; 1999 Jan 15; 274(3):1257-66. PubMed ID: 9880494
    [Abstract] [Full Text] [Related]

  • 20. Astrocyte differentiation of fetal neuroepithelial cells by interleukin-11 via activation of a common cytokine signal transducer, gp130, and a transcription factor, STAT3.
    Yanagisawa M, Nakashima K, Arakawa H, Ikenaka K, Yoshida K, Kishimoto T, Hisatsune T, Taga T.
    J Neurochem; 2000 Apr 15; 74(4):1498-504. PubMed ID: 10737606
    [Abstract] [Full Text] [Related]

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