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170 related items for PubMed ID: 12364343

  • 1. Regulation of TSC2 by 14-3-3 binding.
    Li Y, Inoki K, Yeung R, Guan KL.
    J Biol Chem; 2002 Nov 22; 277(47):44593-6. PubMed ID: 12364343
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  • 2. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling.
    Inoki K, Li Y, Zhu T, Wu J, Guan KL.
    Nat Cell Biol; 2002 Sep 22; 4(9):648-57. PubMed ID: 12172553
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  • 3. 14-3-3beta binds to and negatively regulates the tuberous sclerosis complex 2 (TSC2) tumor suppressor gene product, tuberin.
    Shumway SD, Li Y, Xiong Y.
    J Biol Chem; 2003 Jan 24; 278(4):2089-92. PubMed ID: 12468542
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  • 4. Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase.
    Roux PP, Ballif BA, Anjum R, Gygi SP, Blenis J.
    Proc Natl Acad Sci U S A; 2004 Sep 14; 101(37):13489-94. PubMed ID: 15342917
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  • 5. The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3.
    Li Y, Inoki K, Vacratsis P, Guan KL.
    J Biol Chem; 2003 Apr 18; 278(16):13663-71. PubMed ID: 12582162
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  • 6. Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling.
    Tee AR, Fingar DC, Manning BD, Kwiatkowski DJ, Cantley LC, Blenis J.
    Proc Natl Acad Sci U S A; 2002 Oct 15; 99(21):13571-6. PubMed ID: 12271141
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  • 8. Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity.
    Li Y, Inoki K, Guan KL.
    Mol Cell Biol; 2004 Sep 15; 24(18):7965-75. PubMed ID: 15340059
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  • 9. Regulation of tuberous sclerosis complex (TSC) function by 14-3-3 proteins.
    Nellist M, Goedbloed MA, Halley DJ.
    Biochem Soc Trans; 2003 Jun 15; 31(Pt 3):587-91. PubMed ID: 12773161
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  • 12. Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome.
    Corradetti MN, Inoki K, Bardeesy N, DePinho RA, Guan KL.
    Genes Dev; 2004 Jul 01; 18(13):1533-8. PubMed ID: 15231735
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  • 13. Aberrant beta-catenin signaling in tuberous sclerosis.
    Mak BC, Kenerson HL, Aicher LD, Barnes EA, Yeung RS.
    Am J Pathol; 2005 Jul 01; 167(1):107-16. PubMed ID: 15972957
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  • 14. Tuberin phosphorylation regulates its interaction with hamartin. Two proteins involved in tuberous sclerosis.
    Aicher LD, Campbell JS, Yeung RS.
    J Biol Chem; 2001 Jun 15; 276(24):21017-21. PubMed ID: 11290735
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  • 15. Phosphorylation of tuberin as a novel mechanism for somatic inactivation of the tuberous sclerosis complex proteins in brain lesions.
    Han S, Santos TM, Puga A, Roy J, Thiele EA, McCollin M, Stemmer-Rachamimov A, Ramesh V.
    Cancer Res; 2004 Feb 01; 64(3):812-6. PubMed ID: 14871804
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  • 20. TSC1 and TSC2: genes that are mutated in the human genetic disorder tuberous sclerosis.
    Sampson JR.
    Biochem Soc Trans; 2003 Jun 01; 31(Pt 3):592-6. PubMed ID: 12773162
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