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Journal Abstract Search

273 related items for PubMed ID: 12368903

  • 1. Structural insights into the membrane-anchoring mechanism of a cholesterol-dependent cytolysin.
    Ramachandran R, Heuck AP, Tweten RK, Johnson AE.
    Nat Struct Biol; 2002 Nov; 9(11):823-7. PubMed ID: 12368903
    [Abstract] [Full Text] [Related]

  • 2. The mechanism of pore assembly for a cholesterol-dependent cytolysin: formation of a large prepore complex precedes the insertion of the transmembrane beta-hairpins.
    Shepard LA, Shatursky O, Johnson AE, Tweten RK.
    Biochemistry; 2000 Aug 22; 39(33):10284-93. PubMed ID: 10956018
    [Abstract] [Full Text] [Related]

  • 3. R468A mutation in perfringolysin O destabilizes toxin structure and induces membrane fusion.
    Kulma M, Kacprzyk-Stokowiec A, Kwiatkowska K, Traczyk G, Sobota A, Dadlez M.
    Biochim Biophys Acta Biomembr; 2017 Jun 22; 1859(6):1075-1088. PubMed ID: 28263714
    [Abstract] [Full Text] [Related]

  • 4. The cholesterol-dependent cytolysin family of gram-positive bacterial toxins.
    Heuck AP, Moe PC, Johnson BB.
    Subcell Biochem; 2010 Jun 22; 51():551-77. PubMed ID: 20213558
    [Abstract] [Full Text] [Related]

  • 5. Vertical collapse of a cytolysin prepore moves its transmembrane beta-hairpins to the membrane.
    Czajkowsky DM, Hotze EM, Shao Z, Tweten RK.
    EMBO J; 2004 Aug 18; 23(16):3206-15. PubMed ID: 15297878
    [Abstract] [Full Text] [Related]

  • 6. Identification of a membrane-spanning domain of the thiol-activated pore-forming toxin Clostridium perfringens perfringolysin O: an alpha-helical to beta-sheet transition identified by fluorescence spectroscopy.
    Shepard LA, Heuck AP, Hamman BD, Rossjohn J, Parker MW, Ryan KR, Johnson AE, Tweten RK.
    Biochemistry; 1998 Oct 13; 37(41):14563-74. PubMed ID: 9772185
    [Abstract] [Full Text] [Related]

  • 7. The mechanism of membrane insertion for a cholesterol-dependent cytolysin: a novel paradigm for pore-forming toxins.
    Shatursky O, Heuck AP, Shepard LA, Rossjohn J, Parker MW, Johnson AE, Tweten RK.
    Cell; 1999 Oct 29; 99(3):293-9. PubMed ID: 10555145
    [Abstract] [Full Text] [Related]

  • 8. Membrane-dependent conformational changes initiate cholesterol-dependent cytolysin oligomerization and intersubunit beta-strand alignment.
    Ramachandran R, Tweten RK, Johnson AE.
    Nat Struct Mol Biol; 2004 Aug 29; 11(8):697-705. PubMed ID: 15235590
    [Abstract] [Full Text] [Related]

  • 9. The domains of a cholesterol-dependent cytolysin undergo a major FRET-detected rearrangement during pore formation.
    Ramachandran R, Tweten RK, Johnson AE.
    Proc Natl Acad Sci U S A; 2005 May 17; 102(20):7139-44. PubMed ID: 15878993
    [Abstract] [Full Text] [Related]

  • 10. Crucial role of perfringolysin O D1 domain in orchestrating structural transitions leading to membrane-perforating pores: a hydrogen-deuterium exchange study.
    Kacprzyk-Stokowiec A, Kulma M, Traczyk G, Kwiatkowska K, Sobota A, Dadlez M.
    J Biol Chem; 2014 Oct 10; 289(41):28738-52. PubMed ID: 25164812
    [Abstract] [Full Text] [Related]

  • 11. The Cholesterol-dependent Cytolysin Membrane-binding Interface Discriminates Lipid Environments of Cholesterol to Support β-Barrel Pore Insertion.
    Farrand AJ, Hotze EM, Sato TK, Wade KR, Wimley WC, Johnson AE, Tweten RK.
    J Biol Chem; 2015 Jul 17; 290(29):17733-17744. PubMed ID: 26032415
    [Abstract] [Full Text] [Related]

  • 12. Assembly and topography of the prepore complex in cholesterol-dependent cytolysins.
    Heuck AP, Tweten RK, Johnson AE.
    J Biol Chem; 2003 Aug 15; 278(33):31218-25. PubMed ID: 12777381
    [Abstract] [Full Text] [Related]

  • 13. The cholesterol-dependent cytolysin signature motif: a critical element in the allosteric pathway that couples membrane binding to pore assembly.
    Dowd KJ, Farrand AJ, Tweten RK.
    PLoS Pathog; 2012 Aug 15; 8(7):e1002787. PubMed ID: 22792065
    [Abstract] [Full Text] [Related]

  • 14. Phospholipid hydrolysis caused by Clostridium perfringens α-toxin facilitates the targeting of perfringolysin O to membrane bilayers.
    Moe PC, Heuck AP.
    Biochemistry; 2010 Nov 09; 49(44):9498-507. PubMed ID: 20886855
    [Abstract] [Full Text] [Related]

  • 15. Mechanism of membrane insertion of a multimeric beta-barrel protein: perfringolysin O creates a pore using ordered and coupled conformational changes.
    Heuck AP, Hotze EM, Tweten RK, Johnson AE.
    Mol Cell; 2000 Nov 09; 6(5):1233-42. PubMed ID: 11106760
    [Abstract] [Full Text] [Related]

  • 16. Interaction of theta-toxin (perfringolysin O), a cholesterol-binding cytolysin, with liposomal membranes: change in the aromatic side chains upon binding and insertion.
    Nakamura M, Sekino N, Iwamoto M, Ohno-Iwashita Y.
    Biochemistry; 1995 May 16; 34(19):6513-20. PubMed ID: 7756282
    [Abstract] [Full Text] [Related]

  • 17. Perfringolysin O structure and mechanism of pore formation as a paradigm for cholesterol-dependent cytolysins.
    Johnson BB, Heuck AP.
    Subcell Biochem; 2014 May 16; 80():63-81. PubMed ID: 24798008
    [Abstract] [Full Text] [Related]

  • 18. Perfringolysin O: The Underrated Clostridium perfringens Toxin?
    Verherstraeten S, Goossens E, Valgaeren B, Pardon B, Timbermont L, Haesebrouck F, Ducatelle R, Deprez P, Wade KR, Tweten R, Van Immerseel F.
    Toxins (Basel); 2015 May 14; 7(5):1702-21. PubMed ID: 26008232
    [Abstract] [Full Text] [Related]

  • 19. The cholesterol-dependent cytolysins.
    Tweten RK, Parker MW, Johnson AE.
    Curr Top Microbiol Immunol; 2001 May 14; 257():15-33. PubMed ID: 11417120
    [Abstract] [Full Text] [Related]

  • 20. Fine-tuning of the stability of β-strands by Y181 in perfringolysin O directs the prepore to pore transition.
    Kulma M, Kacprzyk-Stokowiec A, Traczyk G, Kwiatkowska K, Dadlez M.
    Biochim Biophys Acta Biomembr; 2019 Jan 14; 1861(1):110-122. PubMed ID: 30463694
    [Abstract] [Full Text] [Related]

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