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177 related items for PubMed ID: 12370536

  • 1. Cerulein-induced acute pancreatitis in the rat is significantly ameliorated by treatment with MEK1/2 inhibitors U0126 and PD98059.
    Clemons AP, Holstein DM, Galli A, Saunders C.
    Pancreas; 2002 Oct; 25(3):251-9. PubMed ID: 12370536
    [Abstract] [Full Text] [Related]

  • 2. Protective effects of SP600125 a new inhibitor of c-jun N-terminal kinase (JNK) and extracellular-regulated kinase (ERK1/2) in an experimental model of cerulein-induced pancreatitis.
    Minutoli L, Altavilla D, Marini H, Passaniti M, Bitto A, Seminara P, Venuti FS, Famulari C, Macrì A, Versaci A, Squadrito F.
    Life Sci; 2004 Oct 29; 75(24):2853-66. PubMed ID: 15454338
    [Abstract] [Full Text] [Related]

  • 3. Blockades of mitogen-activated protein kinase and calcineurin both change fibre-type markers in skeletal muscle culture.
    Higginson J, Wackerhage H, Woods N, Schjerling P, Ratkevicius A, Grunnet N, Quistorff B.
    Pflugers Arch; 2002 Dec 29; 445(3):437-43. PubMed ID: 12466948
    [Abstract] [Full Text] [Related]

  • 4. The mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway is involved in formyl-methionyl-leucyl-phenylalanine-induced p47phox phosphorylation in human neutrophils.
    Dewas C, Fay M, Gougerot-Pocidalo MA, El-Benna J.
    J Immunol; 2000 Nov 01; 165(9):5238-44. PubMed ID: 11046057
    [Abstract] [Full Text] [Related]

  • 5. Modulation in the expression of SHP-1, SHP-2 and PTP1B due to the inhibition of MAPKs, cAMP and neutrophils early on in the development of cerulein-induced acute pancreatitis in rats.
    García-Hernández V, Sarmiento N, Sánchez-Bernal C, Matellán L, Calvo JJ, Sánchez-Yagüe J.
    Biochim Biophys Acta; 2014 Feb 01; 1842(2):192-201. PubMed ID: 24225419
    [Abstract] [Full Text] [Related]

  • 6. Effects of mitogen-activated protein kinase signaling pathway inhibition on the development of cerulein-induced acute pancreatitis in mice.
    Mazzon E, Impellizzeri D, Di Paola R, Paterniti I, Esposito E, Cappellani A, Bramanti P, Cuzzocrea S.
    Pancreas; 2012 May 01; 41(4):560-70. PubMed ID: 22228051
    [Abstract] [Full Text] [Related]

  • 7. MEK1/2-ERK1/2 mediates alpha1-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes.
    Xiao L, Pimental DR, Amin JK, Singh K, Sawyer DB, Colucci WS.
    J Mol Cell Cardiol; 2001 Apr 01; 33(4):779-87. PubMed ID: 11273730
    [Abstract] [Full Text] [Related]

  • 8. Mitogen-activated protein kinase kinase negatively modulates ciliary neurotrophic factor-activated choline acetyltransferase gene expression.
    Mellott T, Lopez-Coviella I, Blusztajn JK, Berse B.
    Eur J Biochem; 2002 Feb 01; 269(3):850-8. PubMed ID: 11846786
    [Abstract] [Full Text] [Related]

  • 9. PAR2 exerts local protection against acute pancreatitis via modulation of MAP kinase and MAP kinase phosphatase signaling.
    Namkung W, Yoon JS, Kim KH, Lee MG.
    Am J Physiol Gastrointest Liver Physiol; 2008 Nov 01; 295(5):G886-94. PubMed ID: 18755806
    [Abstract] [Full Text] [Related]

  • 10. CX-659S, a diaminouracil derivative, indirectly inhibits the function of Langerhans cells by blocking the MEK1/2-Erk1/2 pathway in keratinocytes.
    Uchi H, Koga T, Urabe K, Moroi Y, Furue M.
    J Invest Dermatol; 2003 Jun 01; 120(6):983-9. PubMed ID: 12787125
    [Abstract] [Full Text] [Related]

  • 11. U0126 reverses Ki-ras-mediated transformation by blocking both mitogen-activated protein kinase and p70 S6 kinase pathways.
    Fukazawa H, Uehara Y.
    Cancer Res; 2000 Apr 15; 60(8):2104-7. PubMed ID: 10786668
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of CCL11, CCL24, and CCL26-induced degranulation in HL-60 eosinophilic cells by specific inhibitors of MEK1/MEK2, p38 MAP kinase, and PI 3-kinase.
    Badewa AP, Heiman AS.
    Immunopharmacol Immunotoxicol; 2003 May 15; 25(2):145-57. PubMed ID: 12784909
    [Abstract] [Full Text] [Related]

  • 13. Effects of mast-cell stabilization in cerulein-induced acute pancreatitis in rats.
    Yönetçi N, Oruç N, Ozütemiz AO, Celik HA, Yüce G.
    Int J Pancreatol; 2001 May 15; 29(3):163-71. PubMed ID: 12067220
    [Abstract] [Full Text] [Related]

  • 14. Protection against glutamate toxicity through inhibition of the p44/42 mitogen-activated protein kinase pathway in neuronally differentiated P19 cells.
    Grant ER, Errico MA, Emanuel SL, Benjamin D, McMillian MK, Wadsworth SA, Zivin RA, Zhong Z.
    Biochem Pharmacol; 2001 Aug 01; 62(3):283-96. PubMed ID: 11434901
    [Abstract] [Full Text] [Related]

  • 15. PD98059 and U0126 activate AMP-activated protein kinase by increasing the cellular AMP:ATP ratio and not via inhibition of the MAP kinase pathway.
    Dokladda K, Green KA, Pan DA, Hardie DG.
    FEBS Lett; 2005 Jan 03; 579(1):236-40. PubMed ID: 15620719
    [Abstract] [Full Text] [Related]

  • 16. Inhibitors of farnesyl protein transferase and MEK1,2 induce apoptosis in fibroblasts transformed with farnesylated but not geranylgeranylated H-Ras.
    Brassard DL, English JM, Malkowski M, Kirschmeier P, Nagabhushan TL, Bishop WR.
    Exp Cell Res; 2002 Feb 15; 273(2):138-46. PubMed ID: 11822869
    [Abstract] [Full Text] [Related]

  • 17. Guggulsterone attenuates cerulein-induced acute pancreatitis via inhibition of ERK and JNK activation.
    Kim DG, Bae GS, Choi SB, Jo IJ, Shin JY, Lee SK, Kim MJ, Kim MJ, Jeong HW, Choi CM, Seo SH, Choo GC, Seo SW, Song HJ, Park SJ.
    Int Immunopharmacol; 2015 May 15; 26(1):194-202. PubMed ID: 25843255
    [Abstract] [Full Text] [Related]

  • 18. MEK1/2 inhibitors promote Ara-C-induced apoptosis but not loss of Deltapsi(m) in HL-60 cells.
    Yu C, Wang Z, Dent P, Grant S.
    Biochem Biophys Res Commun; 2001 Sep 07; 286(5):1011-8. PubMed ID: 11527401
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of mitogen-activated protein kinase kinase blocks proliferation of neural progenitor cells.
    Learish RD, Bruss MD, Haak-Frendscho M.
    Brain Res Dev Brain Res; 2000 Jul 30; 122(1):97-109. PubMed ID: 10915910
    [Abstract] [Full Text] [Related]

  • 20. p38 map kinase is expressed in the pancreas and is immediately activated following cerulein hyperstimulation.
    Wagner AC, Metzler W, Höfken T, Weber H, Göke B.
    Digestion; 1999 Jul 30; 60(1):41-7. PubMed ID: 9892797
    [Abstract] [Full Text] [Related]

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