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294 related items for PubMed ID: 12386169

  • 1. Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathways.
    Groysman M, Hornstein I, Alcover A, Katzav S.
    J Biol Chem; 2002 Dec 20; 277(51):50121-30. PubMed ID: 12386169
    [Abstract] [Full Text] [Related]

  • 2. Vav, a GDP/GTP nucleotide exchange factor, interacts with GDIs, proteins that inhibit GDP/GTP dissociation.
    Groysman M, Russek CS, Katzav S.
    FEBS Lett; 2000 Feb 04; 467(1):75-80. PubMed ID: 10664460
    [Abstract] [Full Text] [Related]

  • 3. Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte.
    Tartare-Deckert S, Monthouel MN, Charvet C, Foucault I, Van Obberghen E, Bernard A, Altman A, Deckert M.
    J Biol Chem; 2001 Jun 15; 276(24):20849-57. PubMed ID: 11262396
    [Abstract] [Full Text] [Related]

  • 4. A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation.
    Kuhne MR, Ku G, Weiss A.
    J Biol Chem; 2000 Jan 21; 275(3):2185-90. PubMed ID: 10636924
    [Abstract] [Full Text] [Related]

  • 5. Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes.
    Scherle P, Behrens T, Staudt LM.
    Proc Natl Acad Sci U S A; 1993 Aug 15; 90(16):7568-72. PubMed ID: 8356058
    [Abstract] [Full Text] [Related]

  • 6. Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76.
    Charvet C, Canonigo AJ, Billadeau DD, Altman A.
    J Biol Chem; 2005 Apr 15; 280(15):15289-99. PubMed ID: 15708849
    [Abstract] [Full Text] [Related]

  • 7. Beta3 tyrosine phosphorylation and alphavbeta3-mediated adhesion are required for Vav1 association and Rho activation in leukocytes.
    Gao C, Schaefer E, Lakkis M, Blystone SD.
    J Biol Chem; 2005 Apr 15; 280(15):15422-9. PubMed ID: 15699036
    [Abstract] [Full Text] [Related]

  • 8. Immune responses in mice deficient in Ly-GDI, a lymphoid-specific regulator of Rho GTPases.
    Yin L, Schwartzberg P, Scharton-Kersten TM, Staudt L, Lenardo M.
    Mol Immunol; 1997 Apr 15; 34(6):481-91. PubMed ID: 9307064
    [Abstract] [Full Text] [Related]

  • 9. Vav family proteins couple to diverse cell surface receptors.
    Moores SL, Selfors LM, Fredericks J, Breit T, Fujikawa K, Alt FW, Brugge JS, Swat W.
    Mol Cell Biol; 2000 Sep 15; 20(17):6364-73. PubMed ID: 10938113
    [Abstract] [Full Text] [Related]

  • 10. Assessment of roles for the Rho-specific guanine nucleotide dissociation inhibitor Ly-GDI in platelet function: a spatial systems approach.
    Ngo AT, Thierheimer ML, Babur Ö, Rocheleau AD, Huang T, Pang J, Rigg RA, Mitrugno A, Theodorescu D, Burchard J, Nan X, Demir E, McCarty OJ, Aslan JE.
    Am J Physiol Cell Physiol; 2017 Apr 01; 312(4):C527-C536. PubMed ID: 28148498
    [Abstract] [Full Text] [Related]

  • 11. The adaptor protein 3BP2 associates with VAV guanine nucleotide exchange factors to regulate NFAT activation by the B-cell antigen receptor.
    Foucault I, Le Bras S, Charvet C, Moon C, Altman A, Deckert M.
    Blood; 2005 Feb 01; 105(3):1106-13. PubMed ID: 15345594
    [Abstract] [Full Text] [Related]

  • 12. Rho GTPases link cytoskeletal rearrangements and activation processes induced via the tetraspanin CD82 in T lymphocytes.
    Delaguillaumie A, Lagaudrière-Gesbert C, Popoff MR, Conjeaud H.
    J Cell Sci; 2002 Jan 15; 115(Pt 2):433-43. PubMed ID: 11839793
    [Abstract] [Full Text] [Related]

  • 13. Pleiotropic defects in TCR signaling in a Vav-1-null Jurkat T-cell line.
    Cao Y, Janssen EM, Duncan AW, Altman A, Billadeau DD, Abraham RT.
    EMBO J; 2002 Sep 16; 21(18):4809-19. PubMed ID: 12234921
    [Abstract] [Full Text] [Related]

  • 14. Vav modulation of the Ras/MEK/ERK signaling pathway plays a role in NFAT activation and CD69 up-regulation.
    Villalba M, Hernandez J, Deckert M, Tanaka Y, Altman A.
    Eur J Immunol; 2000 Jun 16; 30(6):1587-96. PubMed ID: 10898494
    [Abstract] [Full Text] [Related]

  • 15. Vav1 couples T cell receptor to serum response factor-dependent transcription via a MEK-dependent pathway.
    Charvet C, Auberger P, Tartare-Deckert S, Bernard A, Deckert M.
    J Biol Chem; 2002 May 03; 277(18):15376-84. PubMed ID: 11859076
    [Abstract] [Full Text] [Related]

  • 16. Tyrosine phosphorylation of adaptor protein 3BP2 induces T cell receptor-mediated activation of transcription factor.
    Qu X, Kawauchi-Kamata K, Miah SM, Hatani T, Yamamura H, Sada K.
    Biochemistry; 2005 Mar 15; 44(10):3891-8. PubMed ID: 15751964
    [Abstract] [Full Text] [Related]

  • 17. Vav-Rac1-mediated activation of the c-Jun N-terminal kinase/c-Jun/AP-1 pathway plays a major role in stimulation of the distal NFAT site in the interleukin-2 gene promoter.
    Kaminuma O, Deckert M, Elly C, Liu YC, Altman A.
    Mol Cell Biol; 2001 May 15; 21(9):3126-36. PubMed ID: 11287617
    [Abstract] [Full Text] [Related]

  • 18. Vav1: a key signal transducer downstream of the TCR.
    Tybulewicz VL, Ardouin L, Prisco A, Reynolds LF.
    Immunol Rev; 2003 Apr 15; 192():42-52. PubMed ID: 12670394
    [Abstract] [Full Text] [Related]

  • 19. Association of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathway.
    Bassermann F, Jahn T, Miething C, Seipel P, Bai RY, Coutinho S, Tybulewicz VL, Peschel C, Duyster J.
    J Biol Chem; 2002 Apr 05; 277(14):12437-45. PubMed ID: 11790798
    [Abstract] [Full Text] [Related]

  • 20. The Rho family guanine nucleotide exchange factor Vav-2 regulates the development of cell-mediated cytotoxicity.
    Billadeau DD, Mackie SM, Schoon RA, Leibson PJ.
    J Exp Med; 2000 Aug 07; 192(3):381-92. PubMed ID: 10934226
    [Abstract] [Full Text] [Related]

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