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241 related items for PubMed ID: 12388632

  • 1. 2'-NH(2)-MPTP [1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine] depletes serotonin and norepinephrine in rats: a comparison with 2'-CH(3)-MPTP [1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine].
    Unger EL, Mazzola-Pomietto P, Murphy DL, Andrews AM.
    J Pharmacol Exp Ther; 2002 Nov; 303(2):527-33. PubMed ID: 12388632
    [Abstract] [Full Text] [Related]

  • 2. The role of membrane and vesicular monoamine transporters in the neurotoxic and hypothermic effects of 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine (2'-NH(2)-MPTP).
    Numis AL, Unger EL, Sheridan DL, Chisnell AC, Andrews AM.
    Mol Pharmacol; 2004 Sep; 66(3):718-27. PubMed ID: 15322265
    [Abstract] [Full Text] [Related]

  • 3. Neuronal and astroglial responses to the serotonin and norepinephrine neurotoxin: 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine.
    Luellen BA, Miller DB, Chisnell AC, Murphy DL, O'Callaghan JP, Andrews AM.
    J Pharmacol Exp Ther; 2003 Dec; 307(3):923-31. PubMed ID: 14561848
    [Abstract] [Full Text] [Related]

  • 4. 2'-NH2-MPTP in Swiss Webster mice: evidence for long-term (6-month) depletions in cortical and hippocampal serotonin and norepinephrine, differential protection by selective uptake inhibitors or clorgyline and functional changes in central serotonin neurotransmission.
    Andrews AM, Murphy DL.
    J Pharmacol Exp Ther; 1993 Dec; 267(3):1432-9. PubMed ID: 8263805
    [Abstract] [Full Text] [Related]

  • 5. Transgenic mice with high levels of superoxide dismutase activity are protected from the neurotoxic effects of 2'-NH2-MPTP on serotonergic and noradrenergic nerve terminals.
    Andrews AM, Ladenheim B, Epstein CJ, Cadet JL, Murphy DL.
    Mol Pharmacol; 1996 Dec; 50(6):1511-9. PubMed ID: 8967972
    [Abstract] [Full Text] [Related]

  • 6. Fluoxetine and desipramine selectively attenuate 2'-NH2-MPTP-induced depletions in serotonin and norepinephrine.
    Andrews AM, Murphy DL.
    Eur J Pharmacol; 1993 Dec 07; 250(2):215-21. PubMed ID: 8112382
    [Abstract] [Full Text] [Related]

  • 7. Comparison of 1-methyl-4-(p-chlorophenyl)-1,2,3,6-tetrahydropyridine, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and p-chloroamphetamine as monoamine depletors.
    Fuller RW, Hemrick-Luecke SK, Robertson DW.
    Res Commun Chem Pathol Pharmacol; 1985 Oct 07; 50(1):57-65. PubMed ID: 2417293
    [Abstract] [Full Text] [Related]

  • 8. Rapid and differential losses of in vivo dopamine transporter (DAT) and vesicular monoamine transporter (VMAT2) radioligand binding in MPTP-treated mice.
    Kilbourn MR, Kuszpit K, Sherman P.
    Synapse; 2000 Mar 15; 35(4):250-5. PubMed ID: 10657034
    [Abstract] [Full Text] [Related]

  • 9. 3,4-methylenedioxymethamphetamine (MDMA) administration to rats decreases brain tissue serotonin but not serotonin transporter protein and glial fibrillary acidic protein.
    Wang X, Baumann MH, Xu H, Rothman RB.
    Synapse; 2004 Sep 15; 53(4):240-8. PubMed ID: 15266556
    [Abstract] [Full Text] [Related]

  • 10. Sustained depletion of cortical and hippocampal serotonin and norepinephrine but not striatal dopamine by 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine (2'-NH2-MPTP): a comparative study with 2'-CH3-MPTP and MPTP.
    Andrews AM, Murphy DL.
    J Neurochem; 1993 Mar 15; 60(3):1167-70. PubMed ID: 8094744
    [Abstract] [Full Text] [Related]

  • 11. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in the rat: characterization and age-dependent effects.
    Jarvis MF, Wagner GC.
    Synapse; 1990 Mar 15; 5(2):104-12. PubMed ID: 2309157
    [Abstract] [Full Text] [Related]

  • 12. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1.
    Szapacs ME, Numis AL, Andrews AM.
    Neurobiol Dis; 2004 Aug 15; 16(3):572-80. PubMed ID: 15262269
    [Abstract] [Full Text] [Related]

  • 13. The neurotoxin 2'-NH2-MPTP degenerates serotonin axons and evokes increases in hippocampal BDNF.
    Luellen BA, Szapacs ME, Materese CK, Andrews AM.
    Neuropharmacology; 2006 Mar 15; 50(3):297-308. PubMed ID: 16288930
    [Abstract] [Full Text] [Related]

  • 14. Comparative effects of 1-ethyl- and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridines on catecholamine concentrations in mouse brain and heart.
    Fuller RW, Hemrick-Luecke SK, Robertson DW.
    Res Commun Chem Pathol Pharmacol; 1988 Jan 15; 59(1):129-32. PubMed ID: 3258433
    [Abstract] [Full Text] [Related]

  • 15. Effects of blocking the dopamine biosynthesis and of neurotoxic dopamine depletion with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on voluntary wheel running in mice.
    Leng A, Mura A, Hengerer B, Feldon J, Ferger B.
    Behav Brain Res; 2004 Oct 05; 154(2):375-83. PubMed ID: 15313025
    [Abstract] [Full Text] [Related]

  • 16. Attenuation by dopamine uptake blockers of the inhibitory effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and some of its analogs on NADH-linked metabolism in mouse neostriatal slices.
    Ofori S, Heikkila RE, Nicklas WJ.
    J Pharmacol Exp Ther; 1989 Oct 05; 251(1):258-66. PubMed ID: 2571719
    [Abstract] [Full Text] [Related]

  • 17. Mice lacking alpha-synuclein have an attenuated loss of striatal dopamine following prolonged chronic MPTP administration.
    Drolet RE, Behrouz B, Lookingland KJ, Goudreau JL.
    Neurotoxicology; 2004 Sep 05; 25(5):761-9. PubMed ID: 15288507
    [Abstract] [Full Text] [Related]

  • 18. Effects of duloxetine, an antidepressant drug candidate, on concentrations of monoamines and their metabolites in rats and mice.
    Fuller RW, Hemrick-Luecke SK, Snoddy HD.
    J Pharmacol Exp Ther; 1994 Apr 05; 269(1):132-6. PubMed ID: 7513356
    [Abstract] [Full Text] [Related]

  • 19. Selective alterations of gene expression in mice induced by MPTP.
    Xu Z, Cawthon D, McCastlain KA, Slikker W, Ali SF.
    Synapse; 2005 Jan 05; 55(1):45-51. PubMed ID: 15499605
    [Abstract] [Full Text] [Related]

  • 20. Persistent depletion of striatal dopamine in mice by m-hydroxy-MPTP.
    Fuller RW, Hemrick-Luecke SK.
    Res Commun Chem Pathol Pharmacol; 1986 Aug 05; 53(2):167-72. PubMed ID: 3764080
    [Abstract] [Full Text] [Related]

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