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335 related items for PubMed ID: 12393875

  • 1. Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1.
    Van Leeuwen FN, Olivo C, Grivell S, Giepmans BN, Collard JG, Moolenaar WH.
    J Biol Chem; 2003 Jan 03; 278(1):400-6. PubMed ID: 12393875
    [Abstract] [Full Text] [Related]

  • 2. Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling.
    Stam JC, Michiels F, van der Kammen RA, Moolenaar WH, Collard JG.
    EMBO J; 1998 Jul 15; 17(14):4066-74. PubMed ID: 9670021
    [Abstract] [Full Text] [Related]

  • 3. Rho-dependent, Rho kinase-independent inhibitory regulation of Rac and cell migration by LPA1 receptor in Gi-inactivated CHO cells.
    Sugimoto N, Takuwa N, Yoshioka K, Takuwa Y.
    Exp Cell Res; 2006 Jun 10; 312(10):1899-908. PubMed ID: 16564043
    [Abstract] [Full Text] [Related]

  • 4. The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.
    Leeuwen FN, Kain HE, Kammen RA, Michiels F, Kranenburg OW, Collard JG.
    J Cell Biol; 1997 Nov 03; 139(3):797-807. PubMed ID: 9348295
    [Abstract] [Full Text] [Related]

  • 5. Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs).
    Yamada T, Ohoka Y, Kogo M, Inagaki S.
    J Biol Chem; 2005 May 13; 280(19):19358-63. PubMed ID: 15755723
    [Abstract] [Full Text] [Related]

  • 6. Role of LPA4/p2y9/GPR23 in negative regulation of cell motility.
    Lee Z, Cheng CT, Zhang H, Subler MA, Wu J, Mukherjee A, Windle JJ, Chen CK, Fang X.
    Mol Biol Cell; 2008 Dec 13; 19(12):5435-45. PubMed ID: 18843048
    [Abstract] [Full Text] [Related]

  • 7. Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK.
    Stähle M, Veit C, Bachfischer U, Schierling K, Skripczynski B, Hall A, Gierschik P, Giehl K.
    J Cell Sci; 2003 Sep 15; 116(Pt 18):3835-46. PubMed ID: 12902401
    [Abstract] [Full Text] [Related]

  • 8. Heterotrimeric G protein betagamma subunits stimulate FLJ00018, a guanine nucleotide exchange factor for Rac1 and Cdc42.
    Ueda H, Nagae R, Kozawa M, Morishita R, Kimura S, Nagase T, Ohara O, Yoshida S, Asano T.
    J Biol Chem; 2008 Jan 25; 283(4):1946-53. PubMed ID: 18045877
    [Abstract] [Full Text] [Related]

  • 9. Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3.
    Okamoto H, Takuwa N, Yokomizo T, Sugimoto N, Sakurada S, Shigematsu H, Takuwa Y.
    Mol Cell Biol; 2000 Dec 25; 20(24):9247-61. PubMed ID: 11094076
    [Abstract] [Full Text] [Related]

  • 10. Scaffold proteins IRSp53 and spinophilin regulate localized Rac activation by T-lymphocyte invasion and metastasis protein 1 (TIAM1).
    Rajagopal S, Ji Y, Xu K, Li Y, Wicks K, Liu J, Wong KW, Herman IM, Isberg RR, Buchsbaum RJ.
    J Biol Chem; 2010 Jun 04; 285(23):18060-71. PubMed ID: 20360004
    [Abstract] [Full Text] [Related]

  • 11. Integrin α6β4 cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation.
    O'Connor KL, Chen M, Towers LN.
    Am J Physiol Cell Physiol; 2012 Feb 01; 302(3):C605-14. PubMed ID: 22049212
    [Abstract] [Full Text] [Related]

  • 12. Translocation of the Rac1 guanine nucleotide exchange factor Tiam1 induced by platelet-derived growth factor and lysophosphatidic acid.
    Buchanan FG, Elliot CM, Gibbs M, Exton JH.
    J Biol Chem; 2000 Mar 31; 275(13):9742-8. PubMed ID: 10734127
    [Abstract] [Full Text] [Related]

  • 13. Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform.
    Sugimoto N, Takuwa N, Okamoto H, Sakurada S, Takuwa Y.
    Mol Cell Biol; 2003 Mar 31; 23(5):1534-45. PubMed ID: 12588974
    [Abstract] [Full Text] [Related]

  • 14. Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior.
    Sander EE, ten Klooster JP, van Delft S, van der Kammen RA, Collard JG.
    J Cell Biol; 1999 Nov 29; 147(5):1009-22. PubMed ID: 10579721
    [Abstract] [Full Text] [Related]

  • 15. Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin.
    Buchsbaum RJ, Connolly BA, Feig LA.
    J Biol Chem; 2003 May 23; 278(21):18833-41. PubMed ID: 12531897
    [Abstract] [Full Text] [Related]

  • 16. Activation of RhoA by lysophosphatidic acid and Galpha12/13 subunits in neuronal cells: induction of neurite retraction.
    Kranenburg O, Poland M, van Horck FP, Drechsel D, Hall A, Moolenaar WH.
    Mol Biol Cell; 1999 Jun 23; 10(6):1851-7. PubMed ID: 10359601
    [Abstract] [Full Text] [Related]

  • 17. Regulation of breast cancer cell motility by T-cell lymphoma invasion and metastasis-inducing protein.
    Adams HC, Chen R, Liu Z, Whitehead IP.
    Breast Cancer Res; 2010 Jun 23; 12(5):R69. PubMed ID: 20819206
    [Abstract] [Full Text] [Related]

  • 18. The Rac exchange factor Tiam1 is required for the establishment and maintenance of cadherin-based adhesions.
    Malliri A, van Es S, Huveneers S, Collard JG.
    J Biol Chem; 2004 Jul 16; 279(29):30092-8. PubMed ID: 15138270
    [Abstract] [Full Text] [Related]

  • 19. Suppression of the p53-dependent replicative senescence response by lysophosphatidic acid signaling.
    Kortlever RM, Brummelkamp TR, van Meeteren LA, Moolenaar WH, Bernards R.
    Mol Cancer Res; 2008 Sep 16; 6(9):1452-60. PubMed ID: 18723828
    [Abstract] [Full Text] [Related]

  • 20. Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation.
    Michiels F, Stam JC, Hordijk PL, van der Kammen RA, Ruuls-Van Stalle L, Feltkamp CA, Collard JG.
    J Cell Biol; 1997 Apr 21; 137(2):387-98. PubMed ID: 9128250
    [Abstract] [Full Text] [Related]

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