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189 related items for PubMed ID: 12393885

  • 1. Mitochondrial localization of mutant superoxide dismutase 1 triggers caspase-dependent cell death in a cellular model of familial amyotrophic lateral sclerosis.
    Takeuchi H, Kobayashi Y, Ishigaki S, Doyu M, Sobue G.
    J Biol Chem; 2002 Dec 27; 277(52):50966-72. PubMed ID: 12393885
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  • 2. Dorfin prevents cell death by reducing mitochondrial localizing mutant superoxide dismutase 1 in a neuronal cell model of familial amyotrophic lateral sclerosis.
    Takeuchi H, Niwa J, Hishikawa N, Ishigaki S, Tanaka F, Doyu M, Sobue G.
    J Neurochem; 2004 Apr 27; 89(1):64-72. PubMed ID: 15030390
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  • 3. Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS.
    Higgins CM, Jung C, Ding H, Xu Z.
    J Neurosci; 2002 Mar 15; 22(6):RC215. PubMed ID: 11886899
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  • 4. Cu/Zn superoxide dismutase (SOD1) mutations associated with familial amyotrophic lateral sclerosis (ALS) affect cellular free radical release in the presence of oxidative stress.
    Cookson MR, Menzies FM, Manning P, Eggett CJ, Figlewicz DA, McNeil CJ, Shaw PJ.
    Amyotroph Lateral Scler Other Motor Neuron Disord; 2002 Jun 15; 3(2):75-85. PubMed ID: 12215229
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  • 5. Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice.
    Tobisawa S, Hozumi Y, Arawaka S, Koyama S, Wada M, Nagai M, Aoki M, Itoyama Y, Goto K, Kato T.
    Biochem Biophys Res Commun; 2003 Apr 04; 303(2):496-503. PubMed ID: 12659845
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  • 7. Cell death in amyotrophic lateral sclerosis: interplay between neuronal and glial cells.
    Ferri A, Nencini M, Casciati A, Cozzolino M, Angelini DF, Longone P, Spalloni A, Rotilio G, Carrì MT.
    FASEB J; 2004 Aug 04; 18(11):1261-3. PubMed ID: 15208263
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  • 9. Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells.
    Oh YK, Shin KS, Yuan J, Kang SJ.
    J Neurochem; 2008 Feb 04; 104(4):993-1005. PubMed ID: 18233996
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  • 11. Hsp27 and Hsp70 administered in combination have a potent protective effect against FALS-associated SOD1-mutant-induced cell death in mammalian neuronal cells.
    Patel YJ, Payne Smith MD, de Belleroche J, Latchman DS.
    Brain Res Mol Brain Res; 2005 Apr 04; 134(2):256-74. PubMed ID: 15836922
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  • 12. Mutant SOD1-induced neuronal toxicity is mediated by increased mitochondrial superoxide levels.
    Zimmerman MC, Oberley LW, Flanagan SW.
    J Neurochem; 2007 Aug 04; 102(3):609-18. PubMed ID: 17394531
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  • 17. CuZn superoxide dismutase (SOD1) accumulates in vacuolated mitochondria in transgenic mice expressing amyotrophic lateral sclerosis-linked SOD1 mutations.
    Jaarsma D, Rognoni F, van Duijn W, Verspaget HW, Haasdijk ED, Holstege JC.
    Acta Neuropathol; 2001 Oct 04; 102(4):293-305. PubMed ID: 11603803
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  • 19. Increased mitochondrial antioxidative activity or decreased oxygen free radical propagation prevent mutant SOD1-mediated motor neuron cell death and increase amyotrophic lateral sclerosis-like transgenic mouse survival.
    Liu R, Li B, Flanagan SW, Oberley LW, Gozal D, Qiu M.
    J Neurochem; 2002 Feb 04; 80(3):488-500. PubMed ID: 11905995
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  • 20. Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria.
    Pasinelli P, Belford ME, Lennon N, Bacskai BJ, Hyman BT, Trotti D, Brown RH.
    Neuron; 2004 Jul 08; 43(1):19-30. PubMed ID: 15233914
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