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1134 related items for PubMed ID: 12395317

  • 1. PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival.
    Coutant A, Rescan C, Gilot D, Loyer P, Guguen-Guillouzo C, Baffet G.
    Hepatology; 2002 Nov; 36(5):1079-88. PubMed ID: 12395317
    [Abstract] [Full Text] [Related]

  • 2. IGF-1-stimulated protein synthesis in oligodendrocyte progenitors requires PI3K/mTOR/Akt and MEK/ERK pathways.
    Bibollet-Bahena O, Almazan G.
    J Neurochem; 2009 Jun; 109(5):1440-51. PubMed ID: 19453943
    [Abstract] [Full Text] [Related]

  • 3. Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, insulin growth factor-I, and serum.
    Wlodarski P, Kasprzycka M, Liu X, Marzec M, Robertson ES, Slupianek A, Wasik MA.
    Cancer Res; 2005 Sep 01; 65(17):7800-8. PubMed ID: 16140948
    [Abstract] [Full Text] [Related]

  • 4. Hepatocyte growth factor/scatter factor-induced activation of MEK and PI3K signal pathways contributes to expression of proangiogenic cytokines interleukin-8 and vascular endothelial growth factor in head and neck squamous cell carcinoma.
    Dong G, Chen Z, Li ZY, Yeh NT, Bancroft CC, Van Waes C.
    Cancer Res; 2001 Aug 01; 61(15):5911-8. PubMed ID: 11479233
    [Abstract] [Full Text] [Related]

  • 5. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
    Marzec M, Kasprzycka M, Liu X, El-Salem M, Halasa K, Raghunath PN, Bucki R, Wlodarski P, Wasik MA.
    Oncogene; 2007 Aug 16; 26(38):5606-14. PubMed ID: 17353907
    [Abstract] [Full Text] [Related]

  • 6. Effects of the RAF/MEK/ERK and PI3K/AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells.
    Shelton JG, Steelman LS, Lee JT, Knapp SL, Blalock WL, Moye PW, Franklin RA, Pohnert SC, Mirza AM, McMahon M, McCubrey JA.
    Oncogene; 2003 Apr 24; 22(16):2478-92. PubMed ID: 12717425
    [Abstract] [Full Text] [Related]

  • 7. A role for Akt in epidermal growth factor-stimulated cell cycle progression in cultured hepatocytes: generation of a hyperproliferative window after adenoviral expression of constitutively active Akt.
    Luo Y, Dixon CJ, Hall JF, White PJ, Boarder MR.
    J Pharmacol Exp Ther; 2007 Jun 24; 321(3):884-91. PubMed ID: 17371807
    [Abstract] [Full Text] [Related]

  • 8. Antimitogenic and proapoptotic activities of methylseleninic acid in vascular endothelial cells and associated effects on PI3K-AKT, ERK, JNK and p38 MAPK signaling.
    Wang Z, Jiang C, Ganther H, Lü J.
    Cancer Res; 2001 Oct 01; 61(19):7171-8. PubMed ID: 11585751
    [Abstract] [Full Text] [Related]

  • 9. L-leucine increases [3H]-thymidine incorporation in chicken hepatocytes: involvement of the PKC, PI3K/Akt, ERK1/2, and mTOR signaling pathways.
    Lee MY, Jo SD, Lee JH, Han HJ.
    J Cell Biochem; 2008 Dec 15; 105(6):1410-9. PubMed ID: 18980246
    [Abstract] [Full Text] [Related]

  • 10. Both mitogen-activated protein kinase and phosphatidylinositol 3-kinase signalling are required in epidermal growth factor-induced human trophoblast migration.
    Qiu Q, Yang M, Tsang BK, Gruslin A.
    Mol Hum Reprod; 2004 Sep 15; 10(9):677-84. PubMed ID: 15235105
    [Abstract] [Full Text] [Related]

  • 11. Heparin-binding epidermal growth factor-like growth factor stimulates cell proliferation in cerebral cortical cultures through phosphatidylinositol 3'-kinase and mitogen-activated protein kinase.
    Jin K, Mao XO, Del Rio Guerra G, Jin L, Greenberg DA.
    J Neurosci Res; 2005 Aug 15; 81(4):497-505. PubMed ID: 15952178
    [Abstract] [Full Text] [Related]

  • 12. Activation of RAF/MEK/ERK and PI3K/AKT/mTOR pathways in pituitary adenomas and their effects on downstream effectors.
    Dworakowska D, Wlodek E, Leontiou CA, Igreja S, Cakir M, Teng M, Prodromou N, Góth MI, Grozinsky-Glasberg S, Gueorguiev M, Kola B, Korbonits M, Grossman AB.
    Endocr Relat Cancer; 2009 Dec 15; 16(4):1329-38. PubMed ID: 19620247
    [Abstract] [Full Text] [Related]

  • 13. The PI3K/Akt and mTOR/P70S6K signaling pathways in human uveal melanoma cells: interaction with B-Raf/ERK.
    Babchia N, Calipel A, Mouriaux F, Faussat AM, Mascarelli F.
    Invest Ophthalmol Vis Sci; 2010 Jan 15; 51(1):421-9. PubMed ID: 19661225
    [Abstract] [Full Text] [Related]

  • 14. Both mitogen-activated protein kinase (MAPK)/extracellular-signal-regulated kinases (ERK) 1/2 and phosphatidylinositide-3-OH kinase (PI3K)/Akt pathways regulate activation of E-twenty-six (ETS)-like transcription factor 1 (Elk-1) in U138 glioblastoma cells.
    Mut M, Lule S, Demir O, Kurnaz IA, Vural I.
    Int J Biochem Cell Biol; 2012 Feb 15; 44(2):302-10. PubMed ID: 22085529
    [Abstract] [Full Text] [Related]

  • 15. FRAP-p70s6K signaling is required for pancreatic cancer cell proliferation.
    Shah SA, Potter MW, Ricciardi R, Perugini RA, Callery MP.
    J Surg Res; 2001 May 15; 97(2):123-30. PubMed ID: 11341787
    [Abstract] [Full Text] [Related]

  • 16. Differential regulation of the phosphoinositide 3-kinase and MAP kinase pathways by hepatocyte growth factor vs. insulin-like growth factor-I in myogenic cells.
    Halevy O, Cantley LC.
    Exp Cell Res; 2004 Jul 01; 297(1):224-34. PubMed ID: 15194438
    [Abstract] [Full Text] [Related]

  • 17. Activation and role of MAP kinase-dependent pathways in retinal pigment epithelial cells: ERK and RPE cell proliferation.
    Hecquet C, Lefevre G, Valtink M, Engelmann K, Mascarelli F.
    Invest Ophthalmol Vis Sci; 2002 Sep 01; 43(9):3091-8. PubMed ID: 12202534
    [Abstract] [Full Text] [Related]

  • 18. Cytokine-induced phosphoinositide 3-kinase activity promotes Cdk2 activation in factor-dependent hematopoietic cells.
    Henry MK, Nimbalkar D, Hohl RJ, Quelle FW.
    Exp Cell Res; 2004 Sep 10; 299(1):257-66. PubMed ID: 15302592
    [Abstract] [Full Text] [Related]

  • 19. The role of protein kinase B and mitogen-activated protein kinase in epidermal growth factor and tumor necrosis factor alpha-mediated rat hepatocyte survival and apoptosis.
    Roberts RA, James NH, Cosulich SC.
    Hepatology; 2000 Feb 10; 31(2):420-7. PubMed ID: 10655266
    [Abstract] [Full Text] [Related]

  • 20. Insulin, insulin-like growth factor-I, and platelet-derived growth factor activate extracellular signal-regulated kinase by distinct pathways in muscle cells.
    Tsakiridis T, Tsiani E, Lekas P, Bergman A, Cherepanov V, Whiteside C, Downey GP.
    Biochem Biophys Res Commun; 2001 Oct 19; 288(1):205-11. PubMed ID: 11594774
    [Abstract] [Full Text] [Related]

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