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365 related items for PubMed ID: 12398935

  • 1. Mitochondrial reactive oxygen production is dependent on the aromatic hydrocarbon receptor.
    Senft AP, Dalton TP, Nebert DW, Genter MB, Puga A, Hutchinson RJ, Kerzee JK, Uno S, Shertzer HG.
    Free Radic Biol Med; 2002 Nov 01; 33(9):1268-78. PubMed ID: 12398935
    [Abstract] [Full Text] [Related]

  • 2. Dioxin increases reactive oxygen production in mouse liver mitochondria.
    Senft AP, Dalton TP, Nebert DW, Genter MB, Hutchinson RJ, Shertzer HG.
    Toxicol Appl Pharmacol; 2002 Jan 01; 178(1):15-21. PubMed ID: 11781075
    [Abstract] [Full Text] [Related]

  • 3. Cyp1a2 protects against reactive oxygen production in mouse liver microsomes.
    Shertzer HG, Clay CD, Genter MB, Schneider SN, Nebert DW, Dalton TP.
    Free Radic Biol Med; 2004 Mar 01; 36(5):605-17. PubMed ID: 14980704
    [Abstract] [Full Text] [Related]

  • 4. The role of the dioxin-responsive element cluster between the Cyp1a1 and Cyp1a2 loci in aryl hydrocarbon receptor biology.
    Nukaya M, Moran S, Bradfield CA.
    Proc Natl Acad Sci U S A; 2009 Mar 24; 106(12):4923-8. PubMed ID: 19261855
    [Abstract] [Full Text] [Related]

  • 5. Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice.
    Harrill JA, Hukkanen RR, Lawson M, Martin G, Gilger B, Soldatow V, Lecluyse EL, Budinsky RA, Rowlands JC, Thomas RS.
    Toxicol Appl Pharmacol; 2013 Oct 15; 272(2):503-18. PubMed ID: 23859880
    [Abstract] [Full Text] [Related]

  • 6. Cytotoxicity and mitochondrial dysfunction of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in isolated rat hepatocytes.
    Aly HA, Domènech O.
    Toxicol Lett; 2009 Dec 01; 191(1):79-87. PubMed ID: 19686823
    [Abstract] [Full Text] [Related]

  • 7. Arylhydrocarbon receptor-dependent induction of liver and lung cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in genetically engineered C57BL/6J mice.
    Shimada T, Inoue K, Suzuki Y, Kawai T, Azuma E, Nakajima T, Shindo M, Kurose K, Sugie A, Yamagishi Y, Fujii-Kuriyama Y, Hashimoto M.
    Carcinogenesis; 2002 Jul 01; 23(7):1199-207. PubMed ID: 12117779
    [Abstract] [Full Text] [Related]

  • 8. Glutathione redox state regulates mitochondrial reactive oxygen production.
    Shen D, Dalton TP, Nebert DW, Shertzer HG.
    J Biol Chem; 2005 Jul 08; 280(27):25305-12. PubMed ID: 15883162
    [Abstract] [Full Text] [Related]

  • 9. For dioxin-induced birth defects, mouse or human CYP1A2 in maternal liver protects whereas mouse CYP1A1 and CYP1B1 are inconsequential.
    Dragin N, Dalton TP, Miller ML, Shertzer HG, Nebert DW.
    J Biol Chem; 2006 Jul 07; 281(27):18591-600. PubMed ID: 16636061
    [Abstract] [Full Text] [Related]

  • 10. Altered thyroxin and retinoid metabolic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin in aryl hydrocarbon receptor-null mice.
    Nishimura N, Yonemoto J, Miyabara Y, Fujii-Kuriyama Y, Tohyama C.
    Arch Toxicol; 2005 May 07; 79(5):260-7. PubMed ID: 15902423
    [Abstract] [Full Text] [Related]

  • 11. Comparison of mouse hepatic mitochondrial versus microsomal cytochromes P450 following TCDD treatment.
    Genter MB, Clay CD, Dalton TP, Dong H, Nebert DW, Shertzer HG.
    Biochem Biophys Res Commun; 2006 Apr 21; 342(4):1375-81. PubMed ID: 16516144
    [Abstract] [Full Text] [Related]

  • 12. The aryl hydrocarbon receptor-interacting protein (AIP) is required for dioxin-induced hepatotoxicity but not for the induction of the Cyp1a1 and Cyp1a2 genes.
    Nukaya M, Lin BC, Glover E, Moran SM, Kennedy GD, Bradfield CA.
    J Biol Chem; 2010 Nov 12; 285(46):35599-605. PubMed ID: 20829355
    [Abstract] [Full Text] [Related]

  • 13. Modulation of cytochrome P450 1 (Cyp1) by vanadium in hepatic tissue and isolated hepatocyte of C57BL/6 mice.
    Abdelhamid G, Amara IE, Anwar-Mohamed A, El-Kadi AO.
    Arch Toxicol; 2013 Aug 12; 87(8):1531-43. PubMed ID: 23423713
    [Abstract] [Full Text] [Related]

  • 14. 2,3,7,8 Tetrachlorodibenzo-p-dioxin induction of cytochrome P4501A in cultured rat and human hepatocytes.
    Xu L, Li AP, Kaminski DL, Ruh MF.
    Chem Biol Interact; 2000 Feb 01; 124(3):173-89. PubMed ID: 10728777
    [Abstract] [Full Text] [Related]

  • 15. NTP technical report on the toxicology and carcinogenesis studies of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) (CAS No. 1746-01-6) in female Harlan Sprague-Dawley rats (Gavage Studies).
    National Toxicology Program.
    Natl Toxicol Program Tech Rep Ser; 2006 Apr 01; (521):4-232. PubMed ID: 16835633
    [Abstract] [Full Text] [Related]

  • 16. Polycyclic aromatic hydrocarbon-inducible DNA adducts: evidence by 32P-postlabeling and use of knockout mice for Ah receptor-independent mechanisms of metabolic activation in vivo.
    Kondraganti SR, Fernandez-Salguero P, Gonzalez FJ, Ramos KS, Jiang W, Moorthy B.
    Int J Cancer; 2003 Jan 01; 103(1):5-11. PubMed ID: 12455047
    [Abstract] [Full Text] [Related]

  • 17. Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes.
    Vrzal R, Stejskalova L, Monostory K, Maurel P, Bachleda P, Pavek P, Dvorak Z.
    Chem Biol Interact; 2009 May 15; 179(2-3):288-96. PubMed ID: 19022236
    [Abstract] [Full Text] [Related]

  • 18. Strain differences in the proteome of dioxin-sensitive and dioxin-resistant mice treated with 2,3,7,8-tetrabromodibenzo-p-dioxin.
    Nguyen HT, Tsuchiya MC, Yoo J, Iida M, Agusa T, Hirano M, Kim EY, Miyazaki T, Nose M, Iwata H.
    Arch Toxicol; 2017 Apr 15; 91(4):1763-1782. PubMed ID: 27604104
    [Abstract] [Full Text] [Related]

  • 19. Aryl hydrocarbon receptor ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin enhances liver damage in bile duct-ligated mice.
    Ozeki J, Uno S, Ogura M, Choi M, Maeda T, Sakurai K, Matsuo S, Amano S, Nebert DW, Makishima M.
    Toxicology; 2011 Feb 04; 280(1-2):10-7. PubMed ID: 21095216
    [Abstract] [Full Text] [Related]

  • 20. Dioxin induces Ahr-dependent robust DNA demethylation of the Cyp1a1 promoter via Tdg in the mouse liver.
    Amenya HZ, Tohyama C, Ohsako S.
    Sci Rep; 2016 Oct 07; 6():34989. PubMed ID: 27713569
    [Abstract] [Full Text] [Related]

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