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Journal Abstract Search

101 related items for PubMed ID: 12400014

  • 1. Adaptor protein APS binds the NH2-terminal autoinhibitory domain of guanine nucleotide exchange factor Vav3 and augments its activity.
    Yabana N, Shibuya M.
    Oncogene; 2002 Oct 31; 21(50):7720-9. PubMed ID: 12400014
    [Abstract] [Full Text] [Related]

  • 2. Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation.
    Zeng L, Sachdev P, Yan L, Chan JL, Trenkle T, McClelland M, Welsh J, Wang LH.
    Mol Cell Biol; 2000 Dec 31; 20(24):9212-24. PubMed ID: 11094073
    [Abstract] [Full Text] [Related]

  • 3. Adapter protein with a pleckstrin homology (PH) and an Src homology 2 (SH2) domain (APS) and SH2-B enhance insulin-receptor autophosphorylation, extracellular-signal-regulated kinase and phosphoinositide 3-kinase-dependent signalling.
    Ahmed Z, Pillay TS.
    Biochem J; 2003 Apr 15; 371(Pt 2):405-12. PubMed ID: 12521378
    [Abstract] [Full Text] [Related]

  • 4. Tyrosine phosphorylation of adaptor protein 3BP2 induces T cell receptor-mediated activation of transcription factor.
    Qu X, Kawauchi-Kamata K, Miah SM, Hatani T, Yamamura H, Sada K.
    Biochemistry; 2005 Mar 15; 44(10):3891-8. PubMed ID: 15751964
    [Abstract] [Full Text] [Related]

  • 5. Vav transformation requires activation of multiple GTPases and regulation of gene expression.
    Palmby TR, Abe K, Karnoub AE, Der CJ.
    Mol Cancer Res; 2004 Dec 15; 2(12):702-11. PubMed ID: 15634759
    [Abstract] [Full Text] [Related]

  • 6. Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76.
    Charvet C, Canonigo AJ, Billadeau DD, Altman A.
    J Biol Chem; 2005 Apr 15; 280(15):15289-99. PubMed ID: 15708849
    [Abstract] [Full Text] [Related]

  • 7. Vav-family proteins in T-cell signalling.
    Tybulewicz VL.
    Curr Opin Immunol; 2005 Jun 15; 17(3):267-74. PubMed ID: 15886116
    [Abstract] [Full Text] [Related]

  • 8. Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor.
    Roskoski R.
    Biochem Biophys Res Commun; 2005 Nov 11; 337(1):1-13. PubMed ID: 16129412
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of mSOS-activity by binding of phosphatidylinositol 4,5-P2 to the mSOS pleckstrin homology domain.
    Jefferson AB, Klippel A, Williams LT.
    Oncogene; 1998 May 07; 16(18):2303-10. PubMed ID: 9620547
    [Abstract] [Full Text] [Related]

  • 10. Critical role of the pleckstrin homology and cysteine-rich domains in Vav signaling and transforming activity.
    Palmby TR, Abe K, Der CJ.
    J Biol Chem; 2002 Oct 18; 277(42):39350-9. PubMed ID: 12177050
    [Abstract] [Full Text] [Related]

  • 11. The adapter protein APS associates with the multifunctional docking sites Tyr-568 and Tyr-936 in c-Kit.
    Wollberg P, Lennartsson J, Gottfridsson E, Yoshimura A, Rönnstrand L.
    Biochem J; 2003 Mar 15; 370(Pt 3):1033-8. PubMed ID: 12444928
    [Abstract] [Full Text] [Related]

  • 12. C-terminal SH3 domain of CrkII regulates the assembly and function of the DOCK180/ELMO Rac-GEF.
    Akakura S, Kar B, Singh S, Cho L, Tibrewal N, Sanokawa-Akakura R, Reichman C, Ravichandran KS, Birge RB.
    J Cell Physiol; 2005 Jul 15; 204(1):344-51. PubMed ID: 15700267
    [Abstract] [Full Text] [Related]

  • 13. Global conformational rearrangements during the activation of the GDP/GTP exchange factor Vav3.
    Llorca O, Arias-Palomo E, Zugaza JL, Bustelo XR.
    EMBO J; 2005 Apr 06; 24(7):1330-40. PubMed ID: 15775967
    [Abstract] [Full Text] [Related]

  • 14. GEF at work: Vav in protruding filopodia.
    Kranewitter WJ, Danninger C, Gimona M.
    Cell Motil Cytoskeleton; 2001 Jul 06; 49(3):154-60. PubMed ID: 11668584
    [Abstract] [Full Text] [Related]

  • 15. Structure and ligand recognition of the PB1 domain: a novel protein module binding to the PC motif.
    Terasawa H, Noda Y, Ito T, Hatanaka H, Ichikawa S, Ogura K, Sumimoto H, Inagaki F.
    EMBO J; 2001 Aug 01; 20(15):3947-56. PubMed ID: 11483498
    [Abstract] [Full Text] [Related]

  • 16. Vav proteins, adaptors and cell signaling.
    Bustelo XR.
    Oncogene; 2001 Oct 01; 20(44):6372-81. PubMed ID: 11607839
    [Abstract] [Full Text] [Related]

  • 17. Distinct role of phosphatidylinositol 3-kinase and Rho family GTPases in Vav3-induced cell transformation, cell motility, and morphological changes.
    Sachdev P, Zeng L, Wang LH.
    J Biol Chem; 2002 May 17; 277(20):17638-48. PubMed ID: 11884391
    [Abstract] [Full Text] [Related]

  • 18. v-Src induces Shc binding to tyrosine 63 in the cytoplasmic domain of the LDL receptor-related protein 1.
    Barnes H, Ackermann EJ, van der Geer P.
    Oncogene; 2003 Jun 05; 22(23):3589-97. PubMed ID: 12789267
    [Abstract] [Full Text] [Related]

  • 19. Vav3 is regulated during the cell cycle and effects cell division.
    Fujikawa K, Inoue Y, Sakai M, Koyama Y, Nishi S, Funada R, Alt FW, Swat W.
    Proc Natl Acad Sci U S A; 2002 Apr 02; 99(7):4313-8. PubMed ID: 11917103
    [Abstract] [Full Text] [Related]

  • 20. Isoform-specific insertion near the Grb2-binding domain modulates the intrinsic guanine nucleotide exchange activity of hSos1.
    Rojas JM, Subleski M, Coque JJ, Guerrero C, Saez R, Li BQ, Lopez E, Zarich N, Aroca P, Kamata T, Santos E.
    Oncogene; 1999 Mar 04; 18(9):1651-61. PubMed ID: 10208427
    [Abstract] [Full Text] [Related]

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