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160 related items for PubMed ID: 12409295
1. Folding and function of the troponin tail domain. Effects of cardiomyopathic troponin T mutations. Hinkle A, Tobacman LS. J Biol Chem; 2003 Jan 03; 278(1):506-13. PubMed ID: 12409295 [Abstract] [Full Text] [Related]
2. Roles for the troponin tail domain in thin filament assembly and regulation. A deletional study of cardiac troponin T. Hinkle A, Goranson A, Butters CA, Tobacman LS. J Biol Chem; 1999 Mar 12; 274(11):7157-64. PubMed ID: 10066775 [Abstract] [Full Text] [Related]
3. Mapping the domain of troponin T responsible for the activation of actomyosin ATPase activity. Identification of residues involved in binding to actin. Oliveira DM, Nakaie CR, Sousa AD, Farah CS, Reinach FC. J Biol Chem; 2000 Sep 08; 275(36):27513-9. PubMed ID: 10852909 [Abstract] [Full Text] [Related]
4. The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments. Galińska A, Hatch V, Craig R, Murphy AM, Van Eyk JE, Wang CL, Lehman W, Foster DB. Circ Res; 2010 Mar 05; 106(4):705-11. PubMed ID: 20035081 [Abstract] [Full Text] [Related]
5. Effects of cardiomyopathic mutations on the biochemical and biophysical properties of the human alpha-tropomyosin. Hilario E, da Silva SL, Ramos CH, Bertolini MC. Eur J Biochem; 2004 Oct 05; 271(20):4132-40. PubMed ID: 15479242 [Abstract] [Full Text] [Related]
6. Troponin C Mutations Partially Stabilize the Active State of Regulated Actin and Fully Stabilize the Active State When Paired with Δ14 TnT. Baxley T, Johnson D, Pinto JR, Chalovich JM. Biochemistry; 2017 Jun 13; 56(23):2928-2937. PubMed ID: 28530094 [Abstract] [Full Text] [Related]
7. Functional consequences of troponin T mutations found in hypertrophic cardiomyopathy. Tobacman LS, Lin D, Butters C, Landis C, Back N, Pavlov D, Homsher E. J Biol Chem; 1999 Oct 01; 274(40):28363-70. PubMed ID: 10497196 [Abstract] [Full Text] [Related]
8. Cardiomyopathic tropomyosin mutations that increase thin filament Ca2+ sensitivity and tropomyosin N-domain flexibility. Heller MJ, Nili M, Homsher E, Tobacman LS. J Biol Chem; 2003 Oct 24; 278(43):41742-8. PubMed ID: 12900417 [Abstract] [Full Text] [Related]
9. TNNT2 mutations in the tropomyosin binding region of TNT1 disrupt its role in contractile inhibition and stimulate cardiac dysfunction. Madan A, Viswanathan MC, Woulfe KC, Schmidt W, Sidor A, Liu T, Nguyen TH, Trinh B, Wilson C, Madathil S, Vogler G, O'Rourke B, Biesiadecki BJ, Tobacman LS, Cammarato A. Proc Natl Acad Sci U S A; 2020 Aug 04; 117(31):18822-18831. PubMed ID: 32690703 [Abstract] [Full Text] [Related]
10. N-Terminal Hypervariable Region of Muscle Type Isoforms of Troponin T Differentially Modulates the Affinity of Tropomyosin-Binding Site 1. Amarasinghe C, Jin JP. Biochemistry; 2015 Jun 23; 54(24):3822-30. PubMed ID: 26024675 [Abstract] [Full Text] [Related]
11. Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T. Murakami K, Stewart M, Nozawa K, Tomii K, Kudou N, Igarashi N, Shirakihara Y, Wakatsuki S, Yasunaga T, Wakabayashi T. Proc Natl Acad Sci U S A; 2008 May 20; 105(20):7200-5. PubMed ID: 18483193 [Abstract] [Full Text] [Related]
12. A Drosophila melanogaster model of diastolic dysfunction and cardiomyopathy based on impaired troponin-T function. Viswanathan MC, Kaushik G, Engler AJ, Lehman W, Cammarato A. Circ Res; 2014 Jan 17; 114(2):e6-17. PubMed ID: 24221941 [Abstract] [Full Text] [Related]
14. Stepwise C-Terminal Truncation of Cardiac Troponin T Alters Function at Low and Saturating Ca2. Johnson D, Angus CW, Chalovich JM. Biophys J; 2018 Aug 21; 115(4):702-712. PubMed ID: 30057009 [Abstract] [Full Text] [Related]
16. Disease-causing mutations in cardiac troponin T: identification of a critical tropomyosin-binding region. Palm T, Graboski S, Hitchcock-DeGregori SE, Greenfield NJ. Biophys J; 2001 Nov 21; 81(5):2827-37. PubMed ID: 11606294 [Abstract] [Full Text] [Related]
17. Conformational modulation of slow skeletal muscle troponin T by an NH(2)-terminal metal-binding extension. Jin JP, Chen A, Ogut O, Huang QQ. Am J Physiol Cell Physiol; 2000 Oct 21; 279(4):C1067-77. PubMed ID: 11003587 [Abstract] [Full Text] [Related]