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108 related items for PubMed ID: 12416033

  • 1. Enhancement of the antitumor effect of cyclophosphamide with the hypoxia-selective cytotoxin NLCQ-1 against murine tumors and human xenografts.
    Papadopoulou MV, Ji M, Bloomer WD, Hollingshead MG.
    J Exp Ther Oncol; 2002; 2(5):298-305. PubMed ID: 12416033
    [Abstract] [Full Text] [Related]

  • 2. Therapeutic advantage from combining paclitaxel with the hypoxia-selective cytotoxin NLCQ-1 in murine tumor- or human xenograft-bearing mice.
    Papadopoulou MV, Ji M, Ji X, Bloomer WD, Hollingshead MG.
    Cancer Chemother Pharmacol; 2002 Dec; 50(6):501-8. PubMed ID: 12451478
    [Abstract] [Full Text] [Related]

  • 3. Therapeutic advantage from combining 5-fluorouracil with the hypoxia-selective cytotoxin NLCQ-1 in vivo; comparison with tirapazamine.
    Papadopoulou MV, Ji M, Ji X, Bloomer WD.
    Cancer Chemother Pharmacol; 2002 Oct; 50(4):291-8. PubMed ID: 12357303
    [Abstract] [Full Text] [Related]

  • 4. 4-[3-(2-Nitro-1-imidazolyl)propylamino]-7-chloroquinoline hydrochloride (NLCQ-1), a novel bioreductive agent as radiosensitizer in vitro and in vivo: comparison with tirapazamine.
    Papadopoulou MV, Ji M, Rao MK, Bloomer WD.
    Oncol Res; 2001 Oct; 12(8):325-33. PubMed ID: 11589303
    [Abstract] [Full Text] [Related]

  • 5. Synergistic enhancement of the antitumor effect of taxol by the bioreductive compound NLCQ-1, in vivo: comparison with tirapazamine.
    Papadopoulou MV, Ji M, Bloomer WD.
    Oncol Res; 2002 Oct; 13(1):47-54. PubMed ID: 12201674
    [Abstract] [Full Text] [Related]

  • 6. Hypoxia-dependent retinal toxicity of NLCQ-1 (NSC 709257) in BALB/c mice. Comparison with tirapazamine.
    Papadopoulou MV, Ji M, Bloomer WD.
    Basic Clin Pharmacol Toxicol; 2011 Jun; 108(6):396-9. PubMed ID: 21205223
    [Abstract] [Full Text] [Related]

  • 7. NLCQ-1, a novel hypoxic cytotoxin: potentiation of melphalan, cisDDP and cyclophosphamide in vivo.
    Papadopoulou MV, Ji M, Bloomer WD.
    Int J Radiat Oncol Biol Phys; 1998 Nov 01; 42(4):775-9. PubMed ID: 9845094
    [Abstract] [Full Text] [Related]

  • 8. Schedule-dependent potentiation of chemotherapeutic drugs by the bioreductive compounds NLCQ-1 and tirapazamine against EMT6 tumors in mice.
    Papadopoulou MV, Ji M, Bloomer WD.
    Cancer Chemother Pharmacol; 2001 Aug 01; 48(2):160-8. PubMed ID: 11561782
    [Abstract] [Full Text] [Related]

  • 9. Potentiation of alkylating agents by NLCQ-1 or TPZ in vitro and in vivo.
    Papadopoulou MV, Ji X, Bloomer WD.
    J Exp Ther Oncol; 2006 Aug 01; 5(4):261-72. PubMed ID: 17024967
    [Abstract] [Full Text] [Related]

  • 10. Investigational new drug-directed, 5-day repeat dose toxicity study of 4-[3-(2-nitro-1-imidazolyl)-propylamino]-7-chloroquinoline hydrochloride (NLCQ-1, NSC 709257) administered with or without Taxol in Sprague-Dawley rats.
    Papadopoulou MV, Bloomer WD, Torti VR, Page JG.
    Basic Clin Pharmacol Toxicol; 2010 Jun 01; 106(6):497-504. PubMed ID: 20074267
    [Abstract] [Full Text] [Related]

  • 11. Synergistic interaction between cyclophosphamide or paclitaxel and the bioreductive compound NLCPQ-1, in vivo.
    Papadopoulou MV, Ji M, Bloomer WD.
    Oncol Res; 2003 Jun 01; 13(12):561-6. PubMed ID: 12899246
    [Abstract] [Full Text] [Related]

  • 12. NLCQ-1 (NSC 709257) in combination with radiation against human glioma U251 xenografts.
    Papadopoulou MV, Bloomer WD, Hollingshead MG.
    Anticancer Res; 2005 Jun 01; 25(3B):1865-9. PubMed ID: 16158918
    [Abstract] [Full Text] [Related]

  • 13. 4-[3-(2-Nitro-1-imidazolyl)propylamino]-7-chloroquinoline hydrochloride (NLCQ-1), a novel bioreductive compound as a hypoxia-selective cytotoxin.
    Papadopoulou MV, Ji M, Rao MK, Bloomer WD.
    Oncol Res; 2000 Jun 01; 12(4):185-92. PubMed ID: 11341468
    [Abstract] [Full Text] [Related]

  • 14. Mechanisms involved in the potentiation of paclitaxel or 5-fU by the hypoxic cytotoxin NLCQ-1 (NSC 709257) in vitro.
    Papadopoulou MV, Ji X, Bloomer WD.
    Anticancer Res; 2005 Jun 01; 25(3B):2161-70. PubMed ID: 16158959
    [Abstract] [Full Text] [Related]

  • 15. The hypoxia-selective cytotoxin NLCQ-1 (NSC 709257) controls metastatic disease when used as an adjuvant to radiotherapy.
    Lunt SJ, Cawthorne C, Ali M, Telfer BA, Babur M, Smigova A, Julyan PJ, Price PM, Stratford IJ, Bloomer WD, Papadopoulou MV, Williams KJ.
    Br J Cancer; 2010 Jul 13; 103(2):201-8. PubMed ID: 20588272
    [Abstract] [Full Text] [Related]

  • 16. NLCQ-1 (NSC 709257): exploiting hypoxia with a weak DNA-intercalating bioreductive drug.
    Papadopoulou MV, Bloomer WD.
    Clin Cancer Res; 2003 Nov 15; 9(15):5714-20. PubMed ID: 14654556
    [Abstract] [Full Text] [Related]

  • 17. Investigational new drug-directed toxicology and pharmacokinetic study of 4-[3-(2-nitro-1-imidazolyl)-propylamino]-7-chloroquinoline hydrochloride (NLCQ-1, NSC 709257) in Beagle dogs.
    Papadopoulou MV, Bloomer WD, Torti VR, Page JG.
    Basic Clin Pharmacol Toxicol; 2010 Jun 15; 106(6):511-22. PubMed ID: 20074266
    [Abstract] [Full Text] [Related]

  • 18. Advantage of combining NLCQ-1 (NSC 709257) with radiation in treatment of human head and neck xenografts.
    Papadopoulou MV, Bloomer WD, Taylor AP, Hernandez M, Blumenthal RD, Hollingshead MG.
    Radiat Res; 2007 Jul 15; 168(1):65-71. PubMed ID: 17722994
    [Abstract] [Full Text] [Related]

  • 19. DNA repair mechanisms are involved in the hypoxia-dependent toxicity of NLCQ-1 (NSC 709257) and its synergistic interaction with alkylating agents.
    Papadopoulou MV, Bloomer WD.
    In Vivo; 2007 Jul 15; 21(2):175-80. PubMed ID: 17436565
    [Abstract] [Full Text] [Related]

  • 20. Synergistic interaction between tirapazamine and cyclophosphamide in human breast cancer xenografts.
    Langmuir VK, Rooker JA, Osen M, Mendonca HL, Laderoute KR.
    Cancer Res; 1994 Jun 01; 54(11):2845-7. PubMed ID: 8187065
    [Abstract] [Full Text] [Related]

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