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309 related items for PubMed ID: 12421372

  • 1. Identification of JNK-dependent and -independent components of cerebellar granule neuron apoptosis.
    Harris C, Maroney AC, Johnson EM.
    J Neurochem; 2002 Nov; 83(4):992-1001. PubMed ID: 12421372
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons.
    Harris CA, Deshmukh M, Tsui-Pierchala B, Maroney AC, Johnson EM.
    J Neurosci; 2002 Jan 01; 22(1):103-13. PubMed ID: 11756493
    [Abstract] [Full Text] [Related]

  • 3. A role for mixed lineage kinases in granule cell apoptosis induced by cytoskeletal disruption.
    Müller GJ, Geist MA, Veng LM, Willesen MG, Johansen FF, Leist M, Vaudano E.
    J Neurochem; 2006 Mar 01; 96(5):1242-52. PubMed ID: 16478524
    [Abstract] [Full Text] [Related]

  • 4. C-Jun N-terminal kinases/c-Jun and p38 pathways cooperate in ceramide-induced neuronal apoptosis.
    Willaime-Morawek S, Brami-Cherrier K, Mariani J, Caboche J, Brugg B.
    Neuroscience; 2003 Mar 01; 119(2):387-97. PubMed ID: 12770554
    [Abstract] [Full Text] [Related]

  • 5. An inhibitor of p38 and JNK MAP kinases prevents activation of caspase and apoptosis of cultured cerebellar granule neurons.
    Harada J, Sugimoto M.
    Jpn J Pharmacol; 1999 Mar 01; 79(3):369-78. PubMed ID: 10230866
    [Abstract] [Full Text] [Related]

  • 6. Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons.
    Linseman DA, Phelps RA, Bouchard RJ, Le SS, Laessig TA, McClure ML, Heidenreich KA.
    J Neurosci; 2002 Nov 01; 22(21):9287-97. PubMed ID: 12417654
    [Abstract] [Full Text] [Related]

  • 7. Apoptosis-signal regulating kinase-1 is involved in the low potassium-induced activation of p38 mitogen-activated protein kinase and c-Jun in cultured cerebellar granule neurons.
    Yamagishi S, Yamada M, Koshimizu H, Takai S, Hatanaka H, Takeda K, Ichijo H, Shimoke K, Ikeuchi T.
    J Biochem; 2003 Jun 01; 133(6):719-24. PubMed ID: 12869527
    [Abstract] [Full Text] [Related]

  • 8. The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis.
    Xu Z, Maroney AC, Dobrzanski P, Kukekov NV, Greene LA.
    Mol Cell Biol; 2001 Jul 01; 21(14):4713-24. PubMed ID: 11416147
    [Abstract] [Full Text] [Related]

  • 9. CEP-1347/KT-7515, an inhibitor of SAPK/JNK pathway activation, promotes survival and blocks multiple events associated with Abeta-induced cortical neuron apoptosis.
    Bozyczko-Coyne D, O'Kane TM, Wu ZL, Dobrzanski P, Murthy S, Vaught JL, Scott RW.
    J Neurochem; 2001 May 01; 77(3):849-63. PubMed ID: 11331414
    [Abstract] [Full Text] [Related]

  • 10. Activity deprivation-dependent induction of the proapoptotic BH3-only protein Bim is independent of JNK/c-Jun activation during apoptosis in cerebellar granule neurons.
    Shi L, Gong S, Yuan Z, Ma C, Liu Y, Wang C, Li W, Pi R, Huang S, Chen R, Han Y, Mao Z, Li M.
    Neurosci Lett; 2005 Feb 25; 375(1):7-12. PubMed ID: 15664113
    [Abstract] [Full Text] [Related]

  • 11. An essential role for Rac/Cdc42 GTPases in cerebellar granule neuron survival.
    Linseman DA, Laessig T, Meintzer MK, McClure M, Barth H, Aktories K, Heidenreich KA.
    J Biol Chem; 2001 Oct 19; 276(42):39123-31. PubMed ID: 11509562
    [Abstract] [Full Text] [Related]

  • 12. Comparison of inhibitory effects of brain-derived neurotrophic factor and insulin-like growth factor on low potassium-induced apoptosis and activation of p38 MAPK and c-Jun in cultured cerebellar granule neurons.
    Yamagishi S, Matsumoto T, Yokomaku D, Hatanaka H, Shimoke K, Yamada M, Ikeuchi T.
    Brain Res Mol Brain Res; 2003 Nov 26; 119(2):184-91. PubMed ID: 14625085
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of phosphatidylinositol 3-kinase activity elevates c-Jun N-terminal kinase activity in apoptosis of cultured cerebellar granule neurons.
    Shimoke K, Yamagishi S, Yamada M, Ikeuchi T, Hatanaka H.
    Brain Res Dev Brain Res; 1999 Feb 05; 112(2):245-53. PubMed ID: 9878764
    [Abstract] [Full Text] [Related]

  • 14. p38 mitogen-activated protein kinase regulates low potassium-induced c-Jun phosphorylation and apoptosis in cultured cerebellar granule neurons.
    Yamagishi S, Yamada M, Ishikawa Y, Matsumoto T, Ikeuchi T, Hatanaka H.
    J Biol Chem; 2001 Feb 16; 276(7):5129-33. PubMed ID: 11083864
    [Abstract] [Full Text] [Related]

  • 15. beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation.
    Troy CM, Rabacchi SA, Xu Z, Maroney AC, Connors TJ, Shelanski ML, Greene LA.
    J Neurochem; 2001 Apr 16; 77(1):157-64. PubMed ID: 11279271
    [Abstract] [Full Text] [Related]

  • 16. Mixed-lineage kinase inhibitors require the activation of Trk receptors to maintain long-term neuronal trophism and survival.
    Wang LH, Paden AJ, Johnson EM.
    J Pharmacol Exp Ther; 2005 Mar 16; 312(3):1007-19. PubMed ID: 15525794
    [Abstract] [Full Text] [Related]

  • 17. Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons.
    Coffey ET, Hongisto V, Dickens M, Davis RJ, Courtney MJ.
    J Neurosci; 2000 Oct 15; 20(20):7602-13. PubMed ID: 11027220
    [Abstract] [Full Text] [Related]

  • 18. High K+ and IGF-1 protect cerebellar granule neurons via distinct signaling pathways.
    Zhong J, Deng J, Huang S, Yang X, Lee WH.
    J Neurosci Res; 2004 Mar 15; 75(6):794-806. PubMed ID: 14994340
    [Abstract] [Full Text] [Related]

  • 19. JNK-independent activation of c-Jun during neuronal apoptosis induced by multiple DNA-damaging agents.
    Besirli CG, Johnson EM.
    J Biol Chem; 2003 Jun 20; 278(25):22357-66. PubMed ID: 12684520
    [Abstract] [Full Text] [Related]

  • 20. Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways.
    Weston CR, Balmanno K, Chalmers C, Hadfield K, Molton SA, Ley R, Wagner EF, Cook SJ.
    Oncogene; 2003 Mar 06; 22(9):1281-93. PubMed ID: 12618753
    [Abstract] [Full Text] [Related]

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