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Journal Abstract Search


138 related items for PubMed ID: 12424227

  • 1. Cardiac-specific overexpression of a high Ca2+ affinity mutant of SERCA2a attenuates in vivo pressure overload cardiac hypertrophy.
    Nakayama H, Otsu K, Yamaguchi O, Nishida K, Date MO, Hongo K, Kusakari Y, Toyofuku T, Hikoso S, Kashiwase K, Takeda T, Matsumura Y, Kurihara S, Hori M, Tada M.
    FASEB J; 2003 Jan; 17(1):61-3. PubMed ID: 12424227
    [Abstract] [Full Text] [Related]

  • 2. Cardiac-specific overexpression of sarcolipin in phospholamban null mice impairs myocyte function that is restored by phosphorylation.
    Gramolini AO, Trivieri MG, Oudit GY, Kislinger T, Li W, Patel MM, Emili A, Kranias EG, Backx PH, Maclennan DH.
    Proc Natl Acad Sci U S A; 2006 Feb 14; 103(7):2446-51. PubMed ID: 16461894
    [Abstract] [Full Text] [Related]

  • 3. Cardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a) activity and impairs cardiac function in mice.
    Asahi M, Otsu K, Nakayama H, Hikoso S, Takeda T, Gramolini AO, Trivieri MG, Oudit GY, Morita T, Kusakari Y, Hirano S, Hongo K, Hirotani S, Yamaguchi O, Peterson A, Backx PH, Kurihara S, Hori M, MacLennan DH.
    Proc Natl Acad Sci U S A; 2004 Jun 22; 101(25):9199-204. PubMed ID: 15201433
    [Abstract] [Full Text] [Related]

  • 4. Deletion of the inducible 70-kDa heat shock protein genes in mice impairs cardiac contractile function and calcium handling associated with hypertrophy.
    Kim YK, Suarez J, Hu Y, McDonough PM, Boer C, Dix DJ, Dillmann WH.
    Circulation; 2006 Jun 06; 113(22):2589-97. PubMed ID: 16735677
    [Abstract] [Full Text] [Related]

  • 5. Increased SR Ca2+ cycling contributes to improved contractile performance in SERCA2a-overexpressing transgenic rats.
    Maier LS, Wahl-Schott C, Horn W, Weichert S, Pagel C, Wagner S, Dybkova N, Müller OJ, Näbauer M, Franz WM, Pieske B.
    Cardiovasc Res; 2005 Sep 01; 67(4):636-46. PubMed ID: 15932750
    [Abstract] [Full Text] [Related]

  • 6. Early impairment of calcium handling and altered expression of junctin in hearts of mice overexpressing the beta1-adrenergic receptor.
    Engelhardt S, Boknik P, Keller U, Neumann J, Lohse MJ, Hein L.
    FASEB J; 2001 Dec 01; 15(14):2718-20. PubMed ID: 11606476
    [Abstract] [Full Text] [Related]

  • 7. Overexpression of phospholamban in slow-twitch skeletal muscle is associated with depressed contractile function and muscle remodeling.
    Song Q, Young KB, Chu G, Gulick J, Gerst M, Grupp IL, Robbins J, Kranias EG.
    FASEB J; 2004 Jun 01; 18(9):974-6. PubMed ID: 15059971
    [Abstract] [Full Text] [Related]

  • 8. Enhanced sarcolemmal Ca2+ efflux reduces sarcoplasmic reticulum Ca2+ content and systolic Ca2+ in cardiac hypertrophy.
    Díaz ME, Graham HK, Trafford AW.
    Cardiovasc Res; 2004 Jun 01; 62(3):538-47. PubMed ID: 15158146
    [Abstract] [Full Text] [Related]

  • 9. Intermolecular conformational coupling and free energy exchange enhance the catalytic efficiency of cardiac muscle SERCA2a following the relief of phospholamban inhibition.
    Mahaney JE, Albers RW, Waggoner JR, Kutchai HC, Froehlich JP.
    Biochemistry; 2005 May 31; 44(21):7713-24. PubMed ID: 15909986
    [Abstract] [Full Text] [Related]

  • 10. Presenilin 2 regulates the systolic function of heart by modulating Ca2+ signaling.
    Takeda T, Asahi M, Yamaguchi O, Hikoso S, Nakayama H, Kusakari Y, Kawai M, Hongo K, Higuchi Y, Kashiwase K, Watanabe T, Taniike M, Nakai A, Nishida K, Kurihara S, Donoviel DB, Bernstein A, Tomita T, Iwatsubo T, Hori M, Otsu K.
    FASEB J; 2005 Dec 31; 19(14):2069-71. PubMed ID: 16204356
    [Abstract] [Full Text] [Related]

  • 11. Compromised myocardial energetics in hypertrophied mouse hearts diminish the beneficial effect of overexpressing SERCA2a.
    Pinz I, Tian R, Belke D, Swanson E, Dillmann W, Ingwall JS.
    J Biol Chem; 2011 Mar 25; 286(12):10163-8. PubMed ID: 21278384
    [Abstract] [Full Text] [Related]

  • 12. Constitutive cardiac overexpression of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase delays myocardial failure after myocardial infarction in rats at a cost of increased acute arrhythmias.
    Chen Y, Escoubet B, Prunier F, Amour J, Simonides WS, Vivien B, Lenoir C, Heimburger M, Choqueux C, Gellen B, Riou B, Michel JB, Franz WM, Mercadier JJ.
    Circulation; 2004 Apr 20; 109(15):1898-903. PubMed ID: 15037529
    [Abstract] [Full Text] [Related]

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  • 15. Enhanced myocardial contractility and increased Ca2+ transport function in transgenic hearts expressing the fast-twitch skeletal muscle sarcoplasmic reticulum Ca2+-ATPase.
    Loukianov E, Ji Y, Grupp IL, Kirkpatrick DL, Baker DL, Loukianova T, Grupp G, Lytton J, Walsh RA, Periasamy M.
    Circ Res; 1998 Nov 02; 83(9):889-97. PubMed ID: 9797337
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  • 17. Ca2+/calmodulin-dependent phosphorylation of the Ca2+-ATPase, uncoupled from phospholamban, stimulates Ca2+-pumping in native cardiac sarcoplasmic reticulum.
    Xu A, Narayanan N.
    Biochem Biophys Res Commun; 1999 Apr 29; 258(1):66-72. PubMed ID: 10222236
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  • 18. [Effect of astragalus on calcium accumulation and SERCA2a gene expression in myocardial tissues in rats with pressure overload-induced left ventricular hypertrophy].
    Su D, Xu B, Shi HL, Wu DZ, Dai YL.
    Zhongguo Zhong Yao Za Zhi; 2008 Jul 29; 33(14):1724-7. PubMed ID: 18841778
    [Abstract] [Full Text] [Related]

  • 19. Improving cardiac Ca⁺² transport into the sarcoplasmic reticulum in heart failure: lessons from the ubiquitous SERCA2b Ca⁺² pump.
    Vangheluwe P, Wuytack F.
    Biochem Soc Trans; 2011 Jun 29; 39(3):781-7. PubMed ID: 21599649
    [Abstract] [Full Text] [Related]

  • 20. Phospholamban pentamerization increases sensitivity and dynamic range of cardiac relaxation.
    Funk F, Kronenbitter A, Hackert K, Oebbeke M, Klebe G, Barth M, Koch D, Schmitt JP.
    Cardiovasc Res; 2023 Jul 04; 119(7):1568-1582. PubMed ID: 36869774
    [Abstract] [Full Text] [Related]


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