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223 related items for PubMed ID: 12428923

  • 1. Ceramide induces activation of the mitochondrial/caspases pathway in Jurkat and SCC61 cells sensitive to gamma-radiation but activation of this sequence is defective in radioresistant SQ20B cells.
    Alphonse G, Aloy MT, Broquet P, Gerard JP, Louisot P, Rousson R, Rodriguez-Lafrasse C.
    Int J Radiat Biol; 2002 Sep; 78(9):821-35. PubMed ID: 12428923
    [Abstract] [Full Text] [Related]

  • 2. Overcoming resistance to gamma-rays in squamous carcinoma cells by poly-drug elevation of ceramide levels.
    Alphonse G, Bionda C, Aloy MT, Ardail D, Rousson R, Rodriguez-Lafrasse C.
    Oncogene; 2004 Apr 08; 23(15):2703-15. PubMed ID: 15048093
    [Abstract] [Full Text] [Related]

  • 3. Protective role of Hsp27 protein against gamma radiation-induced apoptosis and radiosensitization effects of Hsp27 gene silencing in different human tumor cells.
    Aloy MT, Hadchity E, Bionda C, Diaz-Latoud C, Claude L, Rousson R, Arrigo AP, Rodriguez-Lafrasse C.
    Int J Radiat Oncol Biol Phys; 2008 Feb 01; 70(2):543-53. PubMed ID: 17980509
    [Abstract] [Full Text] [Related]

  • 4. Increasing endogenous ceramide using inhibitors of sphingolipid metabolism maximizes ionizing radiation-induced mitochondrial injury and apoptotic cell killing.
    Rodriguez-Lafrasse C, Alphonse G, Aloy MT, Ardail D, Gérard JP, Louisot P, Rousson R.
    Int J Cancer; 2002 Oct 20; 101(6):589-98. PubMed ID: 12237902
    [Abstract] [Full Text] [Related]

  • 5. Oxidation of pyridine nucleotides during Fas- and ceramide-induced apoptosis in Jurkat cells: correlation with changes in mitochondria, glutathione depletion, intracellular acidification and caspase 3 activation.
    Gendron MC, Schrantz N, Métivier D, Kroemer G, Maciorowska Z, Sureau F, Koester S, Petit PX.
    Biochem J; 2001 Jan 15; 353(Pt 2):357-67. PubMed ID: 11139401
    [Abstract] [Full Text] [Related]

  • 6. Temporal relationships between ceramide production, caspase activation and mitochondrial dysfunction in cell lines with varying sensitivity to anti-Fas-induced apoptosis.
    Rodriguez-Lafrasse C, Alphonse G, Broquet P, Aloy MT, Louisot P, Rousson R.
    Biochem J; 2001 Jul 15; 357(Pt 2):407-16. PubMed ID: 11439090
    [Abstract] [Full Text] [Related]

  • 7. Ornithine decarboxylase prevents tumor necrosis factor alpha-induced apoptosis by decreasing intracellular reactive oxygen species.
    Liu GY, Hung YC, Hsu PC, Liao YF, Chang WH, Tsay GJ, Hung HC.
    Apoptosis; 2005 May 15; 10(3):569-81. PubMed ID: 15909119
    [Abstract] [Full Text] [Related]

  • 8. Sanguinarine, a benzophenanthridine alkaloid, induces apoptosis in MDA-MB-231 human breast carcinoma cells through a reactive oxygen species-mediated mitochondrial pathway.
    Choi WY, Kim GY, Lee WH, Choi YH.
    Chemotherapy; 2008 May 15; 54(4):279-87. PubMed ID: 18667818
    [Abstract] [Full Text] [Related]

  • 9. Ceramide induces early and late apoptosis in human papilloma virus+ cervical cancer cells by inhibiting reactive oxygen species decay, diminishing the intracellular concentration of glutathione and increasing nuclear factor-kappaB translocation.
    Gutiérrez G, Mendoza C, Montaño LF, López-Marure R.
    Anticancer Drugs; 2007 Feb 15; 18(2):149-59. PubMed ID: 17159601
    [Abstract] [Full Text] [Related]

  • 10. Tumor necrosis factor-alpha sensitizes prostate cancer cells to gamma-irradiation-induced apoptosis.
    Kimura K, Bowen C, Spiegel S, Gelmann EP.
    Cancer Res; 1999 Apr 01; 59(7):1606-14. PubMed ID: 10197636
    [Abstract] [Full Text] [Related]

  • 11. A rapid and transient ROS generation by cadmium triggers apoptosis via caspase-dependent pathway in HepG2 cells and this is inhibited through N-acetylcysteine-mediated catalase upregulation.
    Oh SH, Lim SC.
    Toxicol Appl Pharmacol; 2006 May 01; 212(3):212-23. PubMed ID: 16169029
    [Abstract] [Full Text] [Related]

  • 12. Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines.
    Izeradjene K, Douglas L, Tillman DM, Delaney AB, Houghton JA.
    Cancer Res; 2005 Aug 15; 65(16):7436-45. PubMed ID: 16103097
    [Abstract] [Full Text] [Related]

  • 13. Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells.
    Villena J, Henriquez M, Torres V, Moraga F, Díaz-Elizondo J, Arredondo C, Chiong M, Olea-Azar C, Stutzin A, Lavandero S, Quest AF.
    Free Radic Biol Med; 2008 Mar 15; 44(6):1146-60. PubMed ID: 18191646
    [Abstract] [Full Text] [Related]

  • 14. Ceramide is the key mediator of oxidative stress-induced apoptosis in retinal photoreceptor cells.
    Sanvicens N, Cotter TG.
    J Neurochem; 2006 Sep 15; 98(5):1432-44. PubMed ID: 16923157
    [Abstract] [Full Text] [Related]

  • 15. Ceramide triggers caspase activation during gamma-radiation-induced apoptosis of human glioma cells lacking functional p53.
    Hara S, Nakashima S, Kiyono T, Sawada M, Yoshimura S, Iwama T, Sakai N.
    Oncol Rep; 2004 Jul 15; 12(1):119-23. PubMed ID: 15201971
    [Abstract] [Full Text] [Related]

  • 16. Ceramide and glutathione define two independently regulated pathways of cell death initiated by p53 in Molt-4 leukaemia cells.
    El-Assaad W, Kozhaya L, Araysi S, Panjarian S, Bitar FF, Baz E, El-Sabban ME, Dbaibo GS.
    Biochem J; 2003 Dec 15; 376(Pt 3):725-32. PubMed ID: 12967322
    [Abstract] [Full Text] [Related]

  • 17. Molecular mechanisms of TNF-alpha-induced ceramide formation in human glioma cells: P53-mediated oxidant stress-dependent and -independent pathways.
    Sawada M, Kiyono T, Nakashima S, Shinoda J, Naganawa T, Hara S, Iwama T, Sakai N.
    Cell Death Differ; 2004 Sep 15; 11(9):997-1008. PubMed ID: 15131591
    [Abstract] [Full Text] [Related]

  • 18. The tyrosine kinase Lck is involved in regulation of mitochondrial apoptosis pathways.
    Belka C, Gruber C, Jendrossek V, Wesselborg S, Budach W.
    Oncogene; 2003 Jan 16; 22(2):176-85. PubMed ID: 12527887
    [Abstract] [Full Text] [Related]

  • 19. Ceramide induces caspase-dependent and -independent apoptosis in A-431 cells.
    Zhao S, Yang YN, Song JG.
    J Cell Physiol; 2004 Apr 16; 199(1):47-56. PubMed ID: 14978734
    [Abstract] [Full Text] [Related]

  • 20. Caspase inhibition switches the mode of cell death induced by cyanide by enhancing reactive oxygen species generation and PARP-1 activation.
    Prabhakaran K, Li L, Borowitz JL, Isom GE.
    Toxicol Appl Pharmacol; 2004 Mar 01; 195(2):194-202. PubMed ID: 14998685
    [Abstract] [Full Text] [Related]

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