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190 related items for PubMed ID: 12429567

  • 1. T cell selective apoptosis by a novel immunosuppressant, FTY720, is closely regulated with Bcl-2.
    Nagahara Y, Ikekita M, Shinomiya T.
    Br J Pharmacol; 2002 Dec; 137(7):953-62. PubMed ID: 12429567
    [Abstract] [Full Text] [Related]

  • 2. Immunosuppressant FTY720 induces apoptosis by direct induction of permeability transition and release of cytochrome c from mitochondria.
    Nagahara Y, Ikekita M, Shinomiya T.
    J Immunol; 2000 Sep 15; 165(6):3250-9. PubMed ID: 10975841
    [Abstract] [Full Text] [Related]

  • 3. FTY720 induces apoptosis in multiple myeloma cells and overcomes drug resistance.
    Yasui H, Hideshima T, Raje N, Roccaro AM, Shiraishi N, Kumar S, Hamasaki M, Ishitsuka K, Tai YT, Podar K, Catley L, Mitsiades CS, Richardson PG, Albert R, Brinkmann V, Chauhan D, Anderson KC.
    Cancer Res; 2005 Aug 15; 65(16):7478-84. PubMed ID: 16103102
    [Abstract] [Full Text] [Related]

  • 4. Differential activation of c-Jun NH2-terminal kinase and p38 pathways during FTY720-induced apoptosis of T lymphocytes that is suppressed by the extracellular signal-regulated kinase pathway.
    Matsuda S, Minowa A, Suzuki S, Koyasu S.
    J Immunol; 1999 Mar 15; 162(6):3321-6. PubMed ID: 10092785
    [Abstract] [Full Text] [Related]

  • 5. FTY720, a novel immunosuppressive agent, induces apoptosis in human glioma cells.
    Sonoda Y, Yamamoto D, Sakurai S, Hasegawa M, Aizu-Yokota E, Momoi T, Kasahara T.
    Biochem Biophys Res Commun; 2001 Feb 23; 281(2):282-8. PubMed ID: 11181042
    [Abstract] [Full Text] [Related]

  • 6. FTY720 induced Bcl-associated and Fas-independent apoptosis in human renal cancer cells in vitro and significantly reduced in vivo tumor growth in mouse xenograft.
    Ubai T, Azuma H, Kotake Y, Inamoto T, Takahara K, Ito Y, Kiyama S, Sakamoto T, Horie S, Muto S, Takahara S, Otsuki Y, Katsuoka Y.
    Anticancer Res; 2007 Feb 23; 27(1A):75-88. PubMed ID: 17352219
    [Abstract] [Full Text] [Related]

  • 7. Induction of apoptosis in human bladder cancer cells in vitro and in vivo caused by FTY720 treatment.
    Azuma H, Takahara S, Horie S, Muto S, Otsuki Y, Katsuoka Y.
    J Urol; 2003 Jun 23; 169(6):2372-7. PubMed ID: 12771800
    [Abstract] [Full Text] [Related]

  • 8. Selective cancer cell apoptosis induced by FTY720; evidence for a Bcl-dependent pathway and impairment in ERK activity.
    Azuma H, Horie S, Muto S, Otsuki Y, Matsumoto K, Morimoto J, Gotoh R, Okuyama A, Suzuki S, Katsuoka Y, Takahara S.
    Anticancer Res; 2003 Jun 23; 23(4):3183-93. PubMed ID: 12926052
    [Abstract] [Full Text] [Related]

  • 9. A novel immunosuppressive agent FTY720 induced Akt dephosphorylation in leukemia cells.
    Matsuoka Y, Nagahara Y, Ikekita M, Shinomiya T.
    Br J Pharmacol; 2003 Apr 23; 138(7):1303-12. PubMed ID: 12711631
    [Abstract] [Full Text] [Related]

  • 10. Induction of lymphocyte apoptosis by a novel immunosuppressant FTY720: relation with Fas, Bcl-2 and Bax expression.
    Li XK, Shinomiya T, Enosawa S, Kakefuda T, Amemiya H, Suzuki S.
    Transplant Proc; 1997 Apr 23; 29(1-2):1267-8. PubMed ID: 9123299
    [No Abstract] [Full Text] [Related]

  • 11. T-cell apoptosis triggered by FTY720 via mitochondrial pathway.
    Fujino M, Li XK, Guo L, Kitazawa Y, Funeshima N, Fukuda S, Kimura H, Miyashita T, Okuyama T, Amano T, Suzuki S.
    Transplant Proc; 2001 Apr 23; 33(7-8):3084-5. PubMed ID: 11750325
    [No Abstract] [Full Text] [Related]

  • 12. Elimination of cell-cycle regulators during caspase-3-dependent apoptosis caused by an immunosuppressant, FTY720.
    Lee YS, Nakajima H, Tsuruga M, Magae J.
    Biosci Biotechnol Biochem; 2003 Mar 23; 67(3):467-74. PubMed ID: 12723592
    [Abstract] [Full Text] [Related]

  • 13. Induction of microtubule-damage, mitotic arrest, Bcl-2 phosphorylation, Bak activation, and mitochondria-dependent caspase cascade is involved in human Jurkat T-cell apoptosis by aruncin B from Aruncus dioicus var. kamtschaticus.
    Han CR, Jun do Y, Woo HJ, Jeong SY, Woo MH, Kim YH.
    Bioorg Med Chem Lett; 2012 Jan 15; 22(2):945-53. PubMed ID: 22197393
    [Abstract] [Full Text] [Related]

  • 14. Activation of caspases and mitochondria in FTY720-mediated apoptosis in human T cell line Jurkat.
    Fujino M, Li XK, Guo L, Amano T, Suzuki S.
    Int Immunopharmacol; 2001 Oct 15; 1(11):2011-21. PubMed ID: 11606032
    [Abstract] [Full Text] [Related]

  • 15. Coordinate involvement of cell cycle arrest and apoptosis strengthen the effect of FTY720.
    Nagahara Y, Matsuoka Y, Saito K, Ikekita M, Higuchi S, Shinomiya T.
    Jpn J Cancer Res; 2001 Jun 15; 92(6):680-7. PubMed ID: 11429058
    [Abstract] [Full Text] [Related]

  • 16. A new immunosuppressant, FTY720, induces bcl-2-associated apoptotic cell death in human lymphocytes.
    Suzuki S, Li XK, Enosawa S, Shinomiya T.
    Immunology; 1996 Dec 15; 89(4):518-23. PubMed ID: 9014815
    [Abstract] [Full Text] [Related]

  • 17. FTY720 mediates cytochrome c release from mitochondria during rat thymocyte apoptosis.
    Matsumura M, Tsuchida M, Isoyama N, Takai K, Matsuyama H.
    Transpl Immunol; 2010 Aug 15; 23(4):174-9. PubMed ID: 20600904
    [Abstract] [Full Text] [Related]

  • 18. FTY720 enhances the activation-induced apoptosis of donor T cells and modulates graft-versus-host disease.
    Hashimoto D, Asakura S, Matsuoka K, Sakoda Y, Koyama M, Aoyama K, Tanimoto M, Teshima T.
    Eur J Immunol; 2007 Jan 15; 37(1):271-81. PubMed ID: 17154260
    [Abstract] [Full Text] [Related]

  • 19. Mechanism of mitochondrial 7A6 antigen exposure triggered by distinct apoptotic pathways: involvement of caspases.
    Nagahara Y, Tanaka M, Shinomiya T.
    Cytometry A; 2007 Apr 15; 71(4):232-41. PubMed ID: 17323348
    [Abstract] [Full Text] [Related]

  • 20. Altered expression of signaling genes in Jurkat cells upon FTY720 induced apoptosis.
    Wang F, Tan W, Guo D, Zhu X, Qian K, He S.
    Int J Mol Sci; 2010 Sep 02; 11(9):3087-105. PubMed ID: 20957081
    [Abstract] [Full Text] [Related]

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