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881 related items for PubMed ID: 12429655

  • 1. Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells.
    Peng B, Fleming JB, Breslin T, Grau AM, Fojioka S, Abbruzzese JL, Evans DB, Ayers D, Wathen K, Wu T, Robertson KD, Chiao PJ.
    Clin Cancer Res; 2002 Nov; 8(11):3628-38. PubMed ID: 12429655
    [Abstract] [Full Text] [Related]

  • 2. Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells.
    Grau AM, Zhang L, Wang W, Ruan S, Evans DB, Abbruzzese JL, Zhang W, Chiao PJ.
    Cancer Res; 1997 Sep 15; 57(18):3929-34. PubMed ID: 9307274
    [Abstract] [Full Text] [Related]

  • 3. Smad4-independent regulation of p21/WAF1 by transforming growth factor-beta.
    Ijichi H, Otsuka M, Tateishi K, Ikenoue T, Kawakami T, Kanai F, Arakawa Y, Seki N, Shimizu K, Miyazono K, Kawabe T, Omata M.
    Oncogene; 2004 Feb 05; 23(5):1043-51. PubMed ID: 14762439
    [Abstract] [Full Text] [Related]

  • 4. Overexpression of the tumor suppressor gene Smad4/DPC4 induces p21waf1 expression and growth inhibition in human carcinoma cells.
    Hunt KK, Fleming JB, Abramian A, Zhang L, Evans DB, Chiao PJ.
    Cancer Res; 1998 Dec 15; 58(24):5656-61. PubMed ID: 9865717
    [Abstract] [Full Text] [Related]

  • 5. Expression of Smad4 in the FaDu cell line partially restores TGF-beta growth inhibition but is not sufficient to regulate fibronectin expression or suppress tumorigenicity.
    Hummer BT, Bartlett C, Henry E, Weissman BE.
    J Cell Physiol; 2003 Mar 15; 194(3):289-302. PubMed ID: 12548549
    [Abstract] [Full Text] [Related]

  • 6. A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-beta in pancreatic carcinogenesis.
    Jonckheere N, Perrais M, Mariette C, Batra SK, Aubert JP, Pigny P, Van Seuningen I.
    Oncogene; 2004 Jul 29; 23(34):5729-38. PubMed ID: 15184872
    [Abstract] [Full Text] [Related]

  • 7. Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta.
    Feng XH, Lin X, Derynck R.
    EMBO J; 2000 Oct 02; 19(19):5178-93. PubMed ID: 11013220
    [Abstract] [Full Text] [Related]

  • 8. DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells.
    de Winter JP, Roelen BA, ten Dijke P, van der Burg B, van den Eijnden-van Raaij AJ.
    Oncogene; 1997 Apr 24; 14(16):1891-9. PubMed ID: 9150356
    [Abstract] [Full Text] [Related]

  • 9. DPC4/SMAD4 mediated tumor suppression of colon carcinoma cells is associated with reduced urokinase expression.
    Schwarte-Waldhoff I, Klein S, Blass-Kampmann S, Hintelmann A, Eilert C, Dreschers S, Kalthoff H, Hahn SA, Schmiegel W.
    Oncogene; 1999 May 20; 18(20):3152-8. PubMed ID: 10340387
    [Abstract] [Full Text] [Related]

  • 10. The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer.
    Kleeff J, Ishiwata T, Maruyama H, Friess H, Truong P, Büchler MW, Falb D, Korc M.
    Oncogene; 1999 Sep 23; 18(39):5363-72. PubMed ID: 10498890
    [Abstract] [Full Text] [Related]

  • 11. Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines.
    Rich JN, Zhang M, Datto MB, Bigner DD, Wang XF.
    J Biol Chem; 1999 Dec 03; 274(49):35053-8. PubMed ID: 10574984
    [Abstract] [Full Text] [Related]

  • 12. Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells.
    Duda DG, Sunamura M, Lefter LP, Furukawa T, Yokoyama T, Yatsuoka T, Abe T, Inoue H, Motoi F, Egawa S, Matsuno S, Horii A.
    Oncogene; 2003 Oct 09; 22(44):6857-64. PubMed ID: 14534532
    [Abstract] [Full Text] [Related]

  • 13. Overexpression of transforming growth factor (TGF) beta1 type II receptor restores TGF-beta1 sensitivity and signaling in human prostate cancer cells.
    Guo Y, Kyprianou N.
    Cell Growth Differ; 1998 Feb 09; 9(2):185-93. PubMed ID: 9486855
    [Abstract] [Full Text] [Related]

  • 14. TGF-beta1 acts as a tumor suppressor of human malignant keratinocytes independently of Smad 4 expression and ligand-induced G(1) arrest.
    Paterson IC, Davies M, Stone A, Huntley S, Smith E, Pring M, Eveson JW, Robinson CM, Parkinson EK, Prime SS.
    Oncogene; 2002 Feb 28; 21(10):1616-24. PubMed ID: 11896591
    [Abstract] [Full Text] [Related]

  • 15. Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1.
    Subramanian G, Schwarz RE, Higgins L, McEnroe G, Chakravarty S, Dugar S, Reiss M.
    Cancer Res; 2004 Aug 01; 64(15):5200-11. PubMed ID: 15289325
    [Abstract] [Full Text] [Related]

  • 16. Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-beta.
    Jazag A, Ijichi H, Kanai F, Imamura T, Guleng B, Ohta M, Imamura J, Tanaka Y, Tateishi K, Ikenoue T, Kawakami T, Arakawa Y, Miyagishi M, Taira K, Kawabe T, Omata M.
    Oncogene; 2005 Jan 20; 24(4):662-71. PubMed ID: 15592526
    [Abstract] [Full Text] [Related]

  • 17. The role of p21 in interferon gamma-mediated growth inhibition of human breast cancer cells.
    Gooch JL, Herrera RE, Yee D.
    Cell Growth Differ; 2000 Jun 20; 11(6):335-42. PubMed ID: 10910100
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of the antiproliferative effect of TGFbeta by EGF in primary human ovarian cancer cells.
    Dunfield LD, Nachtigal MW.
    Oncogene; 2003 Jul 24; 22(30):4745-51. PubMed ID: 12879019
    [Abstract] [Full Text] [Related]

  • 19. Deregulated c-Myb expression in murine myeloid leukemias prevents the up-regulation of p15(INK4b) normally associated with differentiation.
    Schmidt M, Koller R, Haviernik P, Bies J, Maciag K, Wolff L.
    Oncogene; 2001 Sep 27; 20(43):6205-14. PubMed ID: 11593429
    [Abstract] [Full Text] [Related]

  • 20. Overexpression of p21(WAF1/CIP1) is an early event in the development of pancreatic intraepithelial neoplasia.
    Biankin AV, Kench JG, Morey AL, Lee CS, Biankin SA, Head DR, Hugh TB, Henshall SM, Sutherland RL.
    Cancer Res; 2001 Dec 15; 61(24):8830-7. PubMed ID: 11751405
    [Abstract] [Full Text] [Related]

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