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258 related items for PubMed ID: 12433058

  • 1. Inhibition of glutathione-related enzymes augments LPS-mediated cytokine biosynthesis: involvement of an IkappaB/NF-kappaB-sensitive pathway in the alveolar epithelium.
    Haddad JJ, Safieh-Garabedian B, Saadé NE, Lauterbach R.
    Int Immunopharmacol; 2002 Oct; 2(11):1567-83. PubMed ID: 12433058
    [Abstract] [Full Text] [Related]

  • 2. L-Buthionine-(S,R)-sulfoximine, an irreversible inhibitor of gamma-glutamylcysteine synthetase, augments LPS-mediated pro-inflammatory cytokine biosynthesis: evidence for the implication of an IkappaB-alpha/NF-kappaB insensitive pathway.
    Haddad JJ.
    Eur Cytokine Netw; 2001 Oct; 12(4):614-24. PubMed ID: 11781188
    [Abstract] [Full Text] [Related]

  • 3. Redox signaling-mediated regulation of lipopolysaccharide-induced proinflammatory cytokine biosynthesis in alveolar epithelial cells.
    Haddad JJ, Land SC.
    Antioxid Redox Signal; 2002 Feb; 4(1):179-93. PubMed ID: 11970852
    [Abstract] [Full Text] [Related]

  • 4. Redox regulation of TNF-alpha biosynthesis: augmentation by irreversible inhibition of gamma-glutamylcysteine synthetase and the involvement of an IkappaB-alpha/NF-kappaB-independent pathway in alveolar epithelial cells.
    Haddad JJ, Saadé NE, Safieh-Garabedian B.
    Cell Signal; 2002 Mar; 14(3):211-8. PubMed ID: 11812649
    [Abstract] [Full Text] [Related]

  • 5. Redox regulation of pro-inflammatory cytokines and IkappaB-alpha/NF-kappaB nuclear translocation and activation.
    Haddad JJ.
    Biochem Biophys Res Commun; 2002 Aug 30; 296(4):847-56. PubMed ID: 12200125
    [Abstract] [Full Text] [Related]

  • 6. Glutathione depletion is associated with augmenting a proinflammatory signal: evidence for an antioxidant/pro-oxidant mechanism regulating cytokines in the alveolar epithelium.
    Haddad JJ.
    Cytokines Cell Mol Ther; 2000 Dec 30; 6(4):177-87. PubMed ID: 11565956
    [Abstract] [Full Text] [Related]

  • 7. The involvement of L-gamma-glutamyl-L-cysteinyl-glycine (glutathione/GSH) in the mechanism of redox signaling mediating MAPK(p38)-dependent regulation of pro-inflammatory cytokine production.
    Haddad JJ.
    Biochem Pharmacol; 2002 Jan 15; 63(2):305-20. PubMed ID: 11841806
    [Abstract] [Full Text] [Related]

  • 8. Alpha-melanocyte-related tripeptide, Lys-d-Pro-Val, ameliorates endotoxin-induced nuclear factor kappaB translocation and activation: evidence for involvement of an interleukin-1beta193-195 receptor antagonism in the alveolar epithelium.
    Haddad JJ, Lauterbach R, Saadé NE, Safieh-Garabedian B, Land SC.
    Biochem J; 2001 Apr 01; 355(Pt 1):29-38. PubMed ID: 11256945
    [Abstract] [Full Text] [Related]

  • 9. A redox microenvironment is essential for MAPK-dependent secretion of pro-inflammatory cytokines: modulation by glutathione (GSH/GSSG) biosynthesis and equilibrium in the alveolar epithelium.
    Haddad JJ.
    Cell Immunol; 2011 Apr 01; 270(1):53-61. PubMed ID: 21550026
    [Abstract] [Full Text] [Related]

  • 10. S-Alk(en)ylmercaptocysteine suppresses LPS-induced pro-inflammatory responses in murine macrophages through inhibition of NF-κB pathway and modulation of thiol redox status.
    Tocmo R, Parkin K.
    Free Radic Biol Med; 2018 Dec 01; 129():548-558. PubMed ID: 30342185
    [Abstract] [Full Text] [Related]

  • 11. Immunopharmacological potential of selective phosphodiesterase inhibition. II. Evidence for the involvement of an inhibitory-kappaB/nuclear factor-kappaB-sensitive pathway in alveolar epithelial cells.
    Haddad JJ, Land SC, Tarnow-Mordi WO, Zembala M, Kowalczyk D, Lauterbach R.
    J Pharmacol Exp Ther; 2002 Feb 01; 300(2):567-76. PubMed ID: 11805218
    [Abstract] [Full Text] [Related]

  • 12. Amiloride blockades lipopolysaccharide-induced proinflammatory cytokine biosynthesis in an IkappaB-alpha/NF-kappaB-dependent mechanism. Evidence for the amplification of an antiinflammatory pathway in the alveolar epithelium.
    Haddad JJ, Land SC.
    Am J Respir Cell Mol Biol; 2002 Jan 01; 26(1):114-26. PubMed ID: 11751211
    [Abstract] [Full Text] [Related]

  • 13. Redox/ROS regulation of lipopolysaccharide-induced mitogen-activated protein kinase (MAPK) activation and MAPK-mediated TNF-alpha biosynthesis.
    Haddad JJ, Land SC.
    Br J Pharmacol; 2002 Jan 01; 135(2):520-36. PubMed ID: 11815388
    [Abstract] [Full Text] [Related]

  • 14. Thiol regulation of pro-inflammatory cytokines reveals a novel immunopharmacological potential of glutathione in the alveolar epithelium.
    Haddad JJ, Safieh-Garabedian B, Saadé NE, Land SC.
    J Pharmacol Exp Ther; 2001 Mar 01; 296(3):996-1005. PubMed ID: 11181934
    [Abstract] [Full Text] [Related]

  • 15. Thymulin and zinc (Zn2+)-mediated inhibition of endotoxin-induced production of proinflammatory cytokines and NF-kappaB nuclear translocation and activation in the alveolar epithelium: unraveling the molecular immunomodulatory, anti-inflammatory effect of thymulin/Zn2+ in vitro.
    Haddad JJ.
    Mol Immunol; 2009 Dec 01; 47(2-3):205-14. PubMed ID: 19850345
    [Abstract] [Full Text] [Related]

  • 16. Glutamine reduces TNF-alpha by enhancing glutathione synthesis in lipopolysaccharide-stimulated alveolar epithelial cells of rats.
    Zhang F, Wang X, Wang W, Li N, Li J.
    Inflammation; 2008 Oct 01; 31(5):344-50. PubMed ID: 18807160
    [Abstract] [Full Text] [Related]

  • 17. The biphasic immunoregulation of pyrimidylpiperazine (Y-40138) is IL-10 sensitive and requires NF-kappa B targeting in the alveolar epithelium.
    Haddad JJ, Safieh-Garabedian B, Saadé NE, Land SC.
    Br J Pharmacol; 2001 May 01; 133(1):49-60. PubMed ID: 11325794
    [Abstract] [Full Text] [Related]

  • 18. Superoxide potentiates NF-kappaB activation and modulates endotoxin-induced cytokine production in alveolar macrophages.
    Ndengele MM, Muscoli C, Wang ZQ, Doyle TM, Matuschak GM, Salvemini D.
    Shock; 2005 Feb 01; 23(2):186-93. PubMed ID: 15665736
    [Abstract] [Full Text] [Related]

  • 19. O(2)-evoked regulation of HIF-1alpha and NF-kappaB in perinatal lung epithelium requires glutathione biosynthesis.
    Haddad JJ, Land SC.
    Am J Physiol Lung Cell Mol Physiol; 2000 Mar 01; 278(3):L492-503. PubMed ID: 10710521
    [Abstract] [Full Text] [Related]

  • 20. Antioxidant/pro-oxidant equilibrium regulates HIF-1alpha and NF-kappa B redox sensitivity. Evidence for inhibition by glutathione oxidation in alveolar epithelial cells.
    Haddad JJ, Olver RE, Land SC.
    J Biol Chem; 2000 Jul 14; 275(28):21130-9. PubMed ID: 10801793
    [Abstract] [Full Text] [Related]

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