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490 related items for PubMed ID: 12438264

  • 1. Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells.
    Mora LB, Buettner R, Seigne J, Diaz J, Ahmad N, Garcia R, Bowman T, Falcone R, Fairclough R, Cantor A, Muro-Cacho C, Livingston S, Karras J, Pow-Sang J, Jove R.
    Cancer Res; 2002 Nov 15; 62(22):6659-66. PubMed ID: 12438264
    [Abstract] [Full Text] [Related]

  • 2. Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells.
    Garcia R, Yu CL, Hudnall A, Catlett R, Nelson KL, Smithgall T, Fujita DJ, Ethier SP, Jove R.
    Cell Growth Differ; 1997 Dec 15; 8(12):1267-76. PubMed ID: 9419415
    [Abstract] [Full Text] [Related]

  • 3. G-quartet oligonucleotides: a new class of signal transducer and activator of transcription 3 inhibitors that suppresses growth of prostate and breast tumors through induction of apoptosis.
    Jing N, Li Y, Xiong W, Sha W, Jing L, Tweardy DJ.
    Cancer Res; 2004 Sep 15; 64(18):6603-9. PubMed ID: 15374974
    [Abstract] [Full Text] [Related]

  • 4. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention.
    Buettner R, Mora LB, Jove R.
    Clin Cancer Res; 2002 Apr 15; 8(4):945-54. PubMed ID: 11948098
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of constitutively activated Stat3 signaling pathway suppresses growth of prostate cancer cells.
    Ni Z, Lou W, Leman ES, Gao AC.
    Cancer Res; 2000 Mar 01; 60(5):1225-8. PubMed ID: 10728680
    [Abstract] [Full Text] [Related]

  • 6. Down-regulation of signal transducer and activator of transcription 3 expression using vector-based small interfering RNAs suppresses growth of human prostate tumor in vivo.
    Gao L, Zhang L, Hu J, Li F, Shao Y, Zhao D, Kalvakolanu DV, Kopecko DJ, Zhao X, Xu DQ.
    Clin Cancer Res; 2005 Sep 01; 11(17):6333-41. PubMed ID: 16144938
    [Abstract] [Full Text] [Related]

  • 7. Constitutive activation of nuclear factor kappaB p50/p65 and Fra-1 and JunD is essential for deregulated interleukin 6 expression in prostate cancer.
    Zerbini LF, Wang Y, Cho JY, Libermann TA.
    Cancer Res; 2003 May 01; 63(9):2206-15. PubMed ID: 12727841
    [Abstract] [Full Text] [Related]

  • 8. Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells.
    Song L, Turkson J, Karras JG, Jove R, Haura EB.
    Oncogene; 2003 Jul 03; 22(27):4150-65. PubMed ID: 12833138
    [Abstract] [Full Text] [Related]

  • 9. STAT proteins: novel molecular targets for cancer drug discovery.
    Turkson J, Jove R.
    Oncogene; 2000 Dec 27; 19(56):6613-26. PubMed ID: 11426647
    [Abstract] [Full Text] [Related]

  • 10. Stat3 enhances the growth of LNCaP human prostate cancer cells in intact and castrated male nude mice.
    DeMiguel F, Lee SO, Lou W, Xiao X, Pflug BR, Nelson JB, Gao AC.
    Prostate; 2002 Jul 01; 52(2):123-9. PubMed ID: 12111703
    [Abstract] [Full Text] [Related]

  • 11. Protein kinase Cepsilon interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancer.
    Aziz MH, Manoharan HT, Church DR, Dreckschmidt NE, Zhong W, Oberley TD, Wilding G, Verma AK.
    Cancer Res; 2007 Sep 15; 67(18):8828-38. PubMed ID: 17875724
    [Abstract] [Full Text] [Related]

  • 12. RNA interference targeting Stat3 inhibits growth and induces apoptosis of human prostate cancer cells.
    Lee SO, Lou W, Qureshi KM, Mehraein-Ghomi F, Trump DL, Gao AC.
    Prostate; 2004 Sep 01; 60(4):303-9. PubMed ID: 15264241
    [Abstract] [Full Text] [Related]

  • 13. Stat3 activation in prostatic carcinomas.
    Dhir R, Ni Z, Lou W, DeMiguel F, Grandis JR, Gao AC.
    Prostate; 2002 Jun 01; 51(4):241-6. PubMed ID: 11987152
    [Abstract] [Full Text] [Related]

  • 14. Epidermal growth factor receptor--mediated stat3 signaling blocks apoptosis in head and neck cancer.
    Rubin Grandis J, Zeng Q, Drenning SD.
    Laryngoscope; 2000 May 01; 110(5 Pt 1):868-74. PubMed ID: 10807365
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells.
    Rahaman SO, Harbor PC, Chernova O, Barnett GH, Vogelbaum MA, Haque SJ.
    Oncogene; 2002 Dec 05; 21(55):8404-13. PubMed ID: 12466961
    [Abstract] [Full Text] [Related]

  • 16. Cell density dependent increase of constitutive signal transducers and activators of transcription 3 activity in melanoma cells is mediated by Janus kinases.
    Kreis S, Munz GA, Haan S, Heinrich PC, Behrmann I.
    Mol Cancer Res; 2007 Dec 05; 5(12):1331-41. PubMed ID: 18171991
    [Abstract] [Full Text] [Related]

  • 17. Modulation of signal transducer and activator of transcription 3 activities by p53 tumor suppressor in breast cancer cells.
    Lin J, Jin X, Rothman K, Lin HJ, Tang H, Burke W.
    Cancer Res; 2002 Jan 15; 62(2):376-80. PubMed ID: 11809683
    [Abstract] [Full Text] [Related]

  • 18. Analysis of signal transducer and activator of transcription 3 (STAT3) in gastrointestinal stromal tumors.
    Paner GP, Silberman S, Hartman G, Micetich KC, Aranha GV, Alkan S.
    Anticancer Res; 2003 Jan 15; 23(3B):2253-60. PubMed ID: 12894500
    [Abstract] [Full Text] [Related]

  • 19. Activated signal transducers and activators of transcription 3 signaling induces CD46 expression and protects human cancer cells from complement-dependent cytotoxicity.
    Buettner R, Huang M, Gritsko T, Karras J, Enkemann S, Mesa T, Nam S, Yu H, Jove R.
    Mol Cancer Res; 2007 Aug 15; 5(8):823-32. PubMed ID: 17699108
    [Abstract] [Full Text] [Related]

  • 20. Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells.
    Gritsko T, Williams A, Turkson J, Kaneko S, Bowman T, Huang M, Nam S, Eweis I, Diaz N, Sullivan D, Yoder S, Enkemann S, Eschrich S, Lee JH, Beam CA, Cheng J, Minton S, Muro-Cacho CA, Jove R.
    Clin Cancer Res; 2006 Jan 01; 12(1):11-9. PubMed ID: 16397018
    [Abstract] [Full Text] [Related]

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