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Journal Abstract Search

134 related items for PubMed ID: 12438937

  • 1. Ligand-dependent aggregation of polyglutamine-expanded androgen receptor in neuronal cells.
    Darrington RS, Butler R, Leigh PN, McPhaul MJ, Gallo JM.
    Neuroreport; 2002 Nov 15; 13(16):2117-20. PubMed ID: 12438937
    [Abstract] [Full Text] [Related]

  • 2. Protective effects of estrogens on polyglutamine-expanded androgen receptor aggregation in mice.
    Darrington RS, Leigh PN, Gallo JM.
    Neurosci Lett; 2003 Oct 16; 350(1):37-40. PubMed ID: 12962912
    [Abstract] [Full Text] [Related]

  • 3. Truncated forms of the androgen receptor are associated with polyglutamine expansion in X-linked spinal and bulbar muscular atrophy.
    Butler R, Leigh PN, McPhaul MJ, Gallo JM.
    Hum Mol Genet; 1998 Jan 16; 7(1):121-7. PubMed ID: 9384612
    [Abstract] [Full Text] [Related]

  • 4. Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy.
    Montie HL, Cho MS, Holder L, Liu Y, Tsvetkov AS, Finkbeiner S, Merry DE.
    Hum Mol Genet; 2009 Jun 01; 18(11):1937-50. PubMed ID: 19279159
    [Abstract] [Full Text] [Related]

  • 5. Antiandrogen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy.
    Renier KJ, Troxell-Smith SM, Johansen JA, Katsuno M, Adachi H, Sobue G, Chua JP, Sun Kim H, Lieberman AP, Breedlove SM, Jordan CL.
    Endocrinology; 2014 Jul 01; 155(7):2624-34. PubMed ID: 24742193
    [Abstract] [Full Text] [Related]

  • 6. Spinal and bulbar muscular atrophy: ligand-dependent pathogenesis and therapeutic perspectives.
    Katsuno M, Adachi H, Tanaka F, Sobue G.
    J Mol Med (Berl); 2004 May 01; 82(5):298-307. PubMed ID: 15133611
    [Abstract] [Full Text] [Related]

  • 7. Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy.
    Katsuno M, Adachi H, Doyu M, Minamiyama M, Sang C, Kobayashi Y, Inukai A, Sobue G.
    Nat Med; 2003 Jun 01; 9(6):768-73. PubMed ID: 12754502
    [Abstract] [Full Text] [Related]

  • 8. [In vitro aggregation and cellular toxicity of mutant androgen receptor protein in spinal and bulbar muscular atrophy].
    Kobayashi Y, Li M, Sobue G.
    Nihon Rinsho; 1999 Apr 01; 57(4):874-9. PubMed ID: 10222782
    [Abstract] [Full Text] [Related]

  • 9. Trinucleotide repeat disease. The androgen receptor in spinal and bulbar muscular atrophy.
    Walcott JL, Merry DE.
    Vitam Horm; 2002 Apr 01; 65():127-47. PubMed ID: 12481545
    [Abstract] [Full Text] [Related]

  • 10. An interdomain interaction of the androgen receptor is required for its aggregation and toxicity in spinal and bulbar muscular atrophy.
    Orr CR, Montie HL, Liu Y, Bolzoni E, Jenkins SC, Wilson EM, Joseph JD, McDonnell DP, Merry DE.
    J Biol Chem; 2010 Nov 12; 285(46):35567-77. PubMed ID: 20826791
    [Abstract] [Full Text] [Related]

  • 11. Neuropathology and therapeutic intervention in spinal and bulbar muscular atrophy.
    Banno H, Katsuno M, Suzuki K, Tanaka F, Sobue G.
    Int J Mol Sci; 2009 Mar 12; 10(3):1000-12. PubMed ID: 19399234
    [Abstract] [Full Text] [Related]

  • 12. Loss of endogenous androgen receptor protein accelerates motor neuron degeneration and accentuates androgen insensitivity in a mouse model of X-linked spinal and bulbar muscular atrophy.
    Thomas PS, Fraley GS, Damian V, Woodke LB, Zapata F, Sopher BL, Plymate SR, La Spada AR.
    Hum Mol Genet; 2006 Jul 15; 15(14):2225-38. PubMed ID: 16772330
    [Abstract] [Full Text] [Related]

  • 13. Effects of antiandrogens on transformation and transcription activation of wild-type and mutated (LNCaP) androgen receptors.
    Berrevoets CA, Veldscholte J, Mulder E.
    J Steroid Biochem Mol Biol; 1993 Dec 15; 46(6):731-6. PubMed ID: 8274406
    [Abstract] [Full Text] [Related]

  • 14. Cleavage, aggregation and toxicity of the expanded androgen receptor in spinal and bulbar muscular atrophy.
    Merry DE, Kobayashi Y, Bailey CK, Taye AA, Fischbeck KH.
    Hum Mol Genet; 1998 Apr 15; 7(4):693-701. PubMed ID: 9499423
    [Abstract] [Full Text] [Related]

  • 15. ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor.
    Yang Z, Chang YJ, Yu IC, Yeh S, Wu CC, Miyamoto H, Merry DE, Sobue G, Chen LM, Chang SS, Chang C.
    Nat Med; 2007 Mar 15; 13(3):348-53. PubMed ID: 17334372
    [Abstract] [Full Text] [Related]

  • 16. B2 attenuates polyglutamine-expanded androgen receptor toxicity in cell and fly models of spinal and bulbar muscular atrophy.
    Palazzolo I, Nedelsky NB, Askew CE, Harmison GG, Kasantsev AG, Taylor JP, Fischbeck KH, Pennuto M.
    J Neurosci Res; 2010 Aug 01; 88(10):2207-16. PubMed ID: 20336775
    [Abstract] [Full Text] [Related]

  • 17. Molecular pathogenesis of spinal and bulbar muscular atrophy.
    Merry DE.
    Brain Res Bull; 2010 Aug 01; 56(3-4):203-7. PubMed ID: 11719251
    [Abstract] [Full Text] [Related]

  • 18. Degradation properties of polyglutamine-expanded human androgen receptor in transfected cells.
    Cullen DA, Leigh PN, Gallo JM.
    Neurosci Lett; 2004 Mar 11; 357(3):175-8. PubMed ID: 15003278
    [Abstract] [Full Text] [Related]

  • 19. Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila.
    Takeyama K, Ito S, Yamamoto A, Tanimoto H, Furutani T, Kanuka H, Miura M, Tabata T, Kato S.
    Neuron; 2002 Aug 29; 35(5):855-64. PubMed ID: 12372281
    [Abstract] [Full Text] [Related]

  • 20. Androgen induced cell death in SHSY5Y neuroblastoma cells expressing wild-type and spinal bulbar muscular atrophy mutant androgen receptors.
    Grierson AJ, Shaw CE, Miller CC.
    Biochim Biophys Acta; 2001 Apr 30; 1536(1):13-20. PubMed ID: 11335100
    [Abstract] [Full Text] [Related]

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