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141 related items for PubMed ID: 12439864

  • 1. Protection against acetaminophen hepatotoxicity by clofibrate pretreatment: role of catalase induction.
    Chen C, Hennig GE, Whiteley HE, Manautou JE.
    J Biochem Mol Toxicol; 2002; 16(5):227-34. PubMed ID: 12439864
    [Abstract] [Full Text] [Related]

  • 2. Role of NAD(P)H:quinone oxidoreductase 1 in clofibrate-mediated hepatoprotection from acetaminophen.
    Moffit JS, Aleksunes LM, Kardas MJ, Slitt AL, Klaassen CD, Manautou JE.
    Toxicology; 2007 Feb 12; 230(2-3):197-206. PubMed ID: 17188792
    [Abstract] [Full Text] [Related]

  • 3. Peroxisome proliferator-activated receptor alpha-null mice lack resistance to acetaminophen hepatotoxicity following clofibrate exposure.
    Chen C, Hennig GE, Whiteley HE, Corton JC, Manautou JE.
    Toxicol Sci; 2000 Oct 12; 57(2):338-44. PubMed ID: 11006363
    [Abstract] [Full Text] [Related]

  • 4. Protection by clofibrate against acetaminophen hepatotoxicity in male CD-1 mice is associated with an early increase in biliary concentration of acetaminophen-glutathione adducts.
    Manautou JE, Tveit A, Hoivik DJ, Khairallah EA, Cohen SD.
    Toxicol Appl Pharmacol; 1996 Sep 12; 140(1):30-8. PubMed ID: 8806867
    [Abstract] [Full Text] [Related]

  • 5. Protection against acetaminophen hepatotoxicity by a single dose of clofibrate: effects on selective protein arylation and glutathione depletion.
    Manautou JE, Emeigh Hart SG, Khairallah EA, Cohen SD.
    Fundam Appl Toxicol; 1996 Feb 12; 29(2):229-37. PubMed ID: 8742320
    [Abstract] [Full Text] [Related]

  • 6. The PPAR activator docosahexaenoic acid prevents acetaminophen hepatotoxicity in male CD-1 mice.
    Nguyen KA, Carbone JM, Silva VM, Chen C, Hennig GE, Whiteley HE, Manautou JE.
    J Toxicol Environ Health A; 1999 Oct 15; 58(3):171-86. PubMed ID: 10522648
    [Abstract] [Full Text] [Related]

  • 7. Clofibrate pretreatment diminishes acetaminophen's selective covalent binding and hepatotoxicity.
    Manautou JE, Hoivik DJ, Tveit A, Hart SG, Khairallah EA, Cohen SD.
    Toxicol Appl Pharmacol; 1994 Dec 15; 129(2):252-63. PubMed ID: 7992315
    [Abstract] [Full Text] [Related]

  • 8. Differential gene expression in mouse liver associated with the hepatoprotective effect of clofibrate.
    Moffit JS, Koza-Taylor PH, Holland RD, Thibodeau MS, Beger RD, Lawton MP, Manautou JE.
    Toxicol Appl Pharmacol; 2007 Jul 15; 222(2):169-79. PubMed ID: 17585979
    [Abstract] [Full Text] [Related]

  • 9. Effects of clofibrate and indocyanine green on the hepatobiliary disposition of acetaminophen and its metabolites in male CD-1 mice.
    Chen C, Hennig GE, McCann DJ, Manautou JE.
    Xenobiotica; 2000 Nov 15; 30(11):1019-32. PubMed ID: 11197064
    [Abstract] [Full Text] [Related]

  • 10. Clofibrate-induced in vitro hepatoprotection against acetaminophen is not due to altered glutathione homeostasis.
    Nicholls-Grzemski FA, Calder IC, Priestly BG, Burcham PC.
    Toxicol Sci; 2000 Jul 15; 56(1):220-8. PubMed ID: 10869471
    [Abstract] [Full Text] [Related]

  • 11. Diverse antioxidants protect against acetaminophen hepatotoxicity.
    Oz HS, McClain CJ, Nagasawa HT, Ray MB, de Villiers WJ, Chen TS.
    J Biochem Mol Toxicol; 2004 Jul 15; 18(6):361-8. PubMed ID: 15674847
    [Abstract] [Full Text] [Related]

  • 12. Protective effects of garlic and related organosulfur compounds on acetaminophen-induced hepatotoxicity in mice.
    Wang EJ, Li Y, Lin M, Chen L, Stein AP, Reuhl KR, Yang CS.
    Toxicol Appl Pharmacol; 1996 Jan 15; 136(1):146-54. PubMed ID: 8560468
    [Abstract] [Full Text] [Related]

  • 13. Repeated dosing with the peroxisome proliferator clofibrate decreases the toxicity of model hepatotoxic agents in male mice.
    Manautou JE, Silva VM, Hennig GE, Whiteley HE.
    Toxicology; 1998 May 15; 127(1-3):1-10. PubMed ID: 9699788
    [Abstract] [Full Text] [Related]

  • 14. Distinct roles of NF-kappaB p50 in the regulation of acetaminophen-induced inflammatory mediator production and hepatotoxicity.
    Dambach DM, Durham SK, Laskin JD, Laskin DL.
    Toxicol Appl Pharmacol; 2006 Mar 01; 211(2):157-65. PubMed ID: 16081117
    [Abstract] [Full Text] [Related]

  • 15. Nonalcoholic steatohepatitic (NASH) mice are protected from higher hepatotoxicity of acetaminophen upon induction of PPARalpha with clofibrate.
    Donthamsetty S, Bhave VS, Mitra MS, Latendresse JR, Mehendale HM.
    Toxicol Appl Pharmacol; 2008 Aug 01; 230(3):327-37. PubMed ID: 18501395
    [Abstract] [Full Text] [Related]

  • 16. S-Adenosylmethionine (SAMe) attenuates acetaminophen hepatotoxicity in C57BL/6 mice.
    Valentovic M, Terneus M, Harmon RC, Carpenter AB.
    Toxicol Lett; 2004 Dec 30; 154(3):165-74. PubMed ID: 15501608
    [Abstract] [Full Text] [Related]

  • 17. Increased hepatotoxicity of acetaminophen in Hsp70i knockout mice.
    Tolson JK, Dix DJ, Voellmy RW, Roberts SM.
    Toxicol Appl Pharmacol; 2006 Jan 01; 210(1-2):157-62. PubMed ID: 16280147
    [Abstract] [Full Text] [Related]

  • 18. Highly expressed protein kinase A inhibitor α and suppression of protein kinase A may potentiate acetaminophen-induced hepatotoxicity.
    Yun JW, Kim M, Cho SD, Lee JY, Bae ON, Lim KM.
    Toxicol Lett; 2014 Aug 17; 229(1):59-65. PubMed ID: 24910983
    [Abstract] [Full Text] [Related]

  • 19. Protective effect of diallyl sulfone against acetaminophen-induced hepatotoxicity in mice.
    Lin MC, Wang EJ, Patten C, Lee MJ, Xiao F, Reuhl KR, Yang CS.
    J Biochem Toxicol; 1996 Aug 17; 11(1):11-20. PubMed ID: 8806047
    [Abstract] [Full Text] [Related]

  • 20. Increased resistance to acetaminophen-induced hepatotoxicity in retrovirus-infected mice.
    Chow HH, Tang Y, Li P, Fisher RL, Brendel K, Watson RR.
    Biopharm Drug Dispos; 1996 Nov 17; 17(8):661-74. PubMed ID: 8950046
    [Abstract] [Full Text] [Related]

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