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102 related items for PubMed ID: 12443779
1. 2-(Dimethylaminomethyl)-tetrahydroisoxazolopyridobenzazepine derivatives. Synthesis of a new 5-HT(2C) antagonist with potential anxiolytic properties. Andrés JI, Alonso JM, Fernández J, Iturrino L, Martínez P, Meert TF, Sipido VK. Bioorg Med Chem Lett; 2002 Dec 16; 12(24):3573-7. PubMed ID: 12443779 [Abstract] [Full Text] [Related]
2. Synthesis and structure-activity relationship of 2-(aminoalkyl)-2,3,3a,8-tetrahydrodibenzo[c,f]isoxazolo[2,3-a]azepine derivatives: a novel series of 5-HT(2A/2C) receptor antagonists. Part 2. Andrés JI, Alcázar J, Alonso JM, Díaz A, Fernández J, Gil P, Iturrino L, Matesanz E, Meert TF, Megens A, Sipido VK. Bioorg Med Chem Lett; 2002 Jan 21; 12(2):249-53. PubMed ID: 11755365 [Abstract] [Full Text] [Related]
3. Synthesis and structure-activity relationship of 2-(aminoalkyl)-3,3a,8,12b-tetrahydro-2H-dibenzocyclohepta[1,2-b]furan derivatives: a novel series of 5-HT(2A/2C) receptor antagonists. Cid J, Alonso JM, Andrés JI, Fernández J, Gil P, Iturrino L, Matesanz E, Meert TF, Megens A, Sipido VK, Trabanco AA. Bioorg Med Chem Lett; 2004 Jun 07; 14(11):2765-71. PubMed ID: 15125929 [Abstract] [Full Text] [Related]
4. Synthesis and structure-activity relationship of 2-(aminoalkyl)-2,3,3a,8-tetrahydrodibenzo[c,f]isoxazolo[2,3-a]azepine derivatives: a novel series of 5-HT(2A/2C) receptor antagonists. Part 1. Andrés JI, Alcázar J, Alonso JM, Díaz A, Fernández J, Gil P, Iturrino L, Matesanz E, Meert TF, Megens A, Sipido VK. Bioorg Med Chem Lett; 2002 Jan 21; 12(2):243-8. PubMed ID: 11755364 [Abstract] [Full Text] [Related]
5. Synthesis and evaluation of 5-HT(2A) and 5-HT(2C) receptor binding affinities of novel pyrimidine derivatives. Bózsing D, Simonek I, Simig G, Jakóczi I, Gacsályi I, Lévay G, Tihanyi K, Schmidt E. Bioorg Med Chem Lett; 2002 Nov 04; 12(21):3097-9. PubMed ID: 12372510 [Abstract] [Full Text] [Related]
6. New serotonin 5-HT(2A), 5-HT(2B), and 5-HT(2C) receptor antagonists: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones. Brea J, Rodrigo J, Carrieri A, Sanz F, Cadavid MI, Enguix MJ, Villazón M, Mengod G, Caro Y, Masaguer CF, Raviña E, Centeno NB, Carotti A, Loza MI. J Med Chem; 2002 Jan 03; 45(1):54-71. PubMed ID: 11754579 [Abstract] [Full Text] [Related]
11. Different regulation of rat 5-HT(2A) and rat 5-HT(2C) receptors in NIH 3T3 cells upon exposure to 5-HT and pipamperone. Oekelen DV, Jurzak M, Van de Wiel D, Van Hecke G, Luyten WH, Leysen JE. Eur J Pharmacol; 2001 Aug 03; 425(1):21-32. PubMed ID: 11672571 [Abstract] [Full Text] [Related]
12. 5-HT3- and 5-HT2C-antagonist properties of cyamemazine: significance for its clinical anxiolytic activity. Alvarez-Guerra M, d'Alché-Birée F, Wolf WA, Vargas F, Dib M, Garay RP. Psychopharmacology (Berl); 2000 Jan 03; 147(4):412-7. PubMed ID: 10672635 [Abstract] [Full Text] [Related]
13. Deramciclane, a putative anxiolytic drug, is a serotonin 5-HT2C receptor inverse agonist but fails to induce 5-HT2C receptor down-regulation. Pälvimäki EP, Majasuo H, Kuoppamäki M, Männistö PT, Syvälahti E, Hietala J. Psychopharmacology (Berl); 1998 Mar 03; 136(2):99-104. PubMed ID: 9551765 [Abstract] [Full Text] [Related]
17. Discovery and SAR of new benzazepines as potent and selective 5-HT(2C) receptor agonists for the treatment of obesity. Smith BM, Smith JM, Tsai JH, Schultz JA, Gilson CA, Estrada SA, Chen RR, Park DM, Prieto EB, Gallardo CS, Sengupta D, Thomsen WJ, Saldana HR, Whelan KT, Menzaghi F, Webb RR, Beeley NR. Bioorg Med Chem Lett; 2005 Mar 01; 15(5):1467-70. PubMed ID: 15713408 [Abstract] [Full Text] [Related]