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616 related items for PubMed ID: 12444918

  • 1. PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization.
    Houslay MD, Adams DR.
    Biochem J; 2003 Feb 15; 370(Pt 1):1-18. PubMed ID: 12444918
    [Abstract] [Full Text] [Related]

  • 2. Ndel1 alters its conformation by sequestering cAMP-specific phosphodiesterase-4D3 (PDE4D3) in a manner that is dynamically regulated through Protein Kinase A (PKA).
    Collins DM, Murdoch H, Dunlop AJ, Charych E, Baillie GS, Wang Q, Herberg FW, Brandon N, Prinz A, Houslay MD.
    Cell Signal; 2008 Dec 15; 20(12):2356-69. PubMed ID: 18845247
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  • 3. The role of ERK2 docking and phosphorylation of PDE4 cAMP phosphodiesterase isoforms in mediating cross-talk between the cAMP and ERK signalling pathways.
    Houslay MD, Baillie GS.
    Biochem Soc Trans; 2003 Dec 15; 31(Pt 6):1186-90. PubMed ID: 14641023
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  • 4. Selective SUMO modification of cAMP-specific phosphodiesterase-4D5 (PDE4D5) regulates the functional consequences of phosphorylation by PKA and ERK.
    Li X, Vadrevu S, Dunlop A, Day J, Advant N, Troeger J, Klussmann E, Jaffrey E, Hay RT, Adams DR, Houslay MD, Baillie GS.
    Biochem J; 2010 Apr 28; 428(1):55-65. PubMed ID: 20196770
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  • 6. Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1).
    MacKenzie SJ, Baillie GS, McPhee I, MacKenzie C, Seamons R, McSorley T, Millen J, Beard MB, van Heeke G, Houslay MD.
    Br J Pharmacol; 2002 Jun 28; 136(3):421-33. PubMed ID: 12023945
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  • 8. Implications of PDE4 structure on inhibitor selectivity across PDE families.
    Ke H.
    Int J Impot Res; 2004 Jun 28; 16 Suppl 1():S24-7. PubMed ID: 15224132
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  • 10. PDE4B5, a novel, super-short, brain-specific cAMP phosphodiesterase-4 variant whose isoform-specifying N-terminal region is identical to that of cAMP phosphodiesterase-4D6 (PDE4D6).
    Cheung YF, Kan Z, Garrett-Engele P, Gall I, Murdoch H, Baillie GS, Camargo LM, Johnson JM, Houslay MD, Castle JC.
    J Pharmacol Exp Ther; 2007 Aug 28; 322(2):600-9. PubMed ID: 17519386
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  • 11. Activation and induction of cyclic AMP phosphodiesterase (PDE4) in rat pulmonary microvascular endothelial cells.
    Zhu B, Kelly J, Vemavarapu L, Thompson WJ, Strada SJ.
    Biochem Pharmacol; 2004 Aug 01; 68(3):479-91. PubMed ID: 15242814
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  • 12. AKAP signaling complexes: getting to the heart of the matter.
    McConnachie G, Langeberg LK, Scott JD.
    Trends Mol Med; 2006 Jul 01; 12(7):317-23. PubMed ID: 16809066
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  • 13. Intracellular targeting of phosphodiesterase-4 underpins compartmentalized cAMP signaling.
    Lynch MJ, Hill EV, Houslay MD.
    Curr Top Dev Biol; 2006 Jul 01; 75():225-59. PubMed ID: 16984814
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  • 14. Seven Dictyostelium discoideum phosphodiesterases degrade three pools of cAMP and cGMP.
    Bader S, Kortholt A, Van Haastert PJ.
    Biochem J; 2007 Feb 15; 402(1):153-61. PubMed ID: 17040207
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  • 15. Crystal structures of the catalytic domain of phosphodiesterase 4B complexed with AMP, 8-Br-AMP, and rolipram.
    Xu RX, Rocque WJ, Lambert MH, Vanderwall DE, Luther MA, Nolte RT.
    J Mol Biol; 2004 Mar 19; 337(2):355-65. PubMed ID: 15003452
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  • 18. Identification of a multifunctional docking site on the catalytic unit of phosphodiesterase-4 (PDE4) that is utilised by multiple interaction partners.
    Houslay KF, Christian F, MacLeod R, Adams DR, Houslay MD, Baillie GS.
    Biochem J; 2017 Feb 15; 474(4):597-609. PubMed ID: 27993970
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  • 19. The oligomerization state determines regulatory properties and inhibitor sensitivity of type 4 cAMP-specific phosphodiesterases.
    Richter W, Conti M.
    J Biol Chem; 2004 Jul 16; 279(29):30338-48. PubMed ID: 15131123
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  • 20. Profiling of functional phosphodiesterase in mesangial cells using a CRE-SEAP-based reporting system.
    Zhu Y, Yao J, Meng Y, Kasai A, Hiramatsu N, Hayakawa K, Miida T, Takeda M, Okada M, Kitamura M.
    Br J Pharmacol; 2006 Jul 16; 148(6):833-44. PubMed ID: 16751794
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