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261 related items for PubMed ID: 12446480

  • 1. Delayed cytokine mRNA expression kinetics after T-lymphocyte costimulation: a quantitative measure of the efficacy of cyclosporin A-based immunosuppression.
    Härtel C, Fricke L, Schumacher N, Kirchner H, Müller-Steinhardt M.
    Clin Chem; 2002 Dec; 48(12):2225-31. PubMed ID: 12446480
    [Abstract] [Full Text] [Related]

  • 2. Individual variability in cyclosporin A sensitivity: the assessment of functional measures on CD28-mediated costimulation of human whole blood T lymphocytes.
    Härtel C, Hammers HJ, Schlenke P, Fricke L, Schumacher N, Kirchner H, Müller-Steinhardt M.
    J Interferon Cytokine Res; 2003 Feb; 23(2):91-9. PubMed ID: 12744774
    [Abstract] [Full Text] [Related]

  • 3. Sensitivity of whole-blood T lymphocytes in individual patients to tacrolimus (FK 506): impact of interleukin-2 mRNA expression as surrogate measure of immunosuppressive effect.
    Härtel C, Schumacher N, Fricke L, Ebel B, Kirchner H, Müller-Steinhardt M.
    Clin Chem; 2004 Jan; 50(1):141-51. PubMed ID: 14709642
    [Abstract] [Full Text] [Related]

  • 4. Cyclosporine A inhibits the mRNA expressions of IL-2, IL-4 and IFN-gamma, but not TNF-alpha, in canine mononuclear cells.
    Kobayashi T, Momoi Y, Iwasaki T.
    J Vet Med Sci; 2007 Sep; 69(9):887-92. PubMed ID: 17917372
    [Abstract] [Full Text] [Related]

  • 5. The pharmacodynamic effect of sirolimus: individual variation of cytokine mRNA expression profiles in human whole blood samples.
    Müller-Steinhardt M, Wortmeier K, Fricke L, Ebel B, Härtel C.
    Immunobiology; 2009 Sep; 214(1):17-26. PubMed ID: 19159823
    [Abstract] [Full Text] [Related]

  • 6. The effect of the CD28 activation pathway on the immunosuppressive action of cyclosporine.
    Hess AD, Bright EC.
    Transplantation; 1991 Jun; 51(6):1232-40. PubMed ID: 1646506
    [Abstract] [Full Text] [Related]

  • 7. Cyclosporin A inhibits the early phase of NF-kappaB/RelA activation induced by CD28 costimulatory signaling to reduce the IL-2 expression in human peripheral T cells.
    Nishiyama S, Manabe N, Kubota Y, Ohnishi H, Kitanaka A, Tokuda M, Taminato T, Ishida T, Takahara J, Tanaka T.
    Int Immunopharmacol; 2005 Apr; 5(4):699-710. PubMed ID: 15710339
    [Abstract] [Full Text] [Related]

  • 8. Interleukin-5 mRNA stability in human T cells is regulated differently than interleukin-2, interleukin-3, interleukin-4, granulocyte/macrophage colony-stimulating factor, and interferon-gamma.
    Umland SP, Razac S, Shah H, Nahrebne DK, Egan RW, Billah MM.
    Am J Respir Cell Mol Biol; 1998 May; 18(5):631-42. PubMed ID: 9569233
    [Abstract] [Full Text] [Related]

  • 9. Role of mRNA stability in the different patterns of cytokine production by CD4+ cells from young and old mice.
    Pioli C, Pucci S, Barile S, Frasca D, Doria G.
    Immunology; 1998 Jul; 94(3):380-7. PubMed ID: 9767421
    [Abstract] [Full Text] [Related]

  • 10. Cytokine mRNA in the joints and draining lymph nodes of rats with adjuvant arthritis and effects of cyclosporin A.
    Ayer LM, Issekutz AC, Waterhouse CC, Stadnyk AW.
    Inflammation; 2000 Oct; 24(5):447-61. PubMed ID: 10921508
    [Abstract] [Full Text] [Related]

  • 11. Simultaneous cross-linking of CD6 and CD28 induces cell proliferation in resting T cells.
    Osorio LM, Rottenberg M, Jondal M, Chow SC.
    Immunology; 1998 Mar; 93(3):358-65. PubMed ID: 9640246
    [Abstract] [Full Text] [Related]

  • 12. Cyclosporin A increases IFN-gamma production by T cells when co-stimulated through CD28.
    Rafiq K, Kasran A, Peng X, Warmerdam PA, Coorevits L, Ceuppens JL, Van Gool SW.
    Eur J Immunol; 1998 May; 28(5):1481-91. PubMed ID: 9603452
    [Abstract] [Full Text] [Related]

  • 13. Evaluation of interleukin-2 mRNA in whole blood as a parameter for monitoring cyclosporine pharmacodynamics.
    Kuzuya T, Kobayashi T, Katayama A, Nagasaka T, Miwa Y, Uchida K, Nakao A, Yamada K.
    Biol Pharm Bull; 2009 Apr; 32(4):604-8. PubMed ID: 19336891
    [Abstract] [Full Text] [Related]

  • 14. Immunosuppressive activity of the immunophilin-binding drug Sanglifehrin A in human whole blood: potent inhibition of interleukin-6 produced by lymphocytes and monocytes.
    Härtel C, Iblher P, Puzik A, Wortmeier K, Ebel B, Schultz C, Müller-Steinhardt M.
    Scand J Immunol; 2006 Jan; 63(1):26-34. PubMed ID: 16398698
    [Abstract] [Full Text] [Related]

  • 15. FK506 potently inhibits T cell activation induced TNF-alpha and IL-1beta production in vitro by human peripheral blood mononuclear cells.
    Sakuma S, Kato Y, Nishigaki F, Sasakawa T, Magari K, Miyata S, Ohkubo Y, Goto T.
    Br J Pharmacol; 2000 Aug; 130(7):1655-63. PubMed ID: 10928971
    [Abstract] [Full Text] [Related]

  • 16. FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. II. FTY720 prolongs skin allograft survival by decreasing T cell infiltration into grafts but not cytokine production in vivo.
    Yanagawa Y, Sugahara K, Kataoka H, Kawaguchi T, Masubuchi Y, Chiba K.
    J Immunol; 1998 Jun 01; 160(11):5493-9. PubMed ID: 9605152
    [Abstract] [Full Text] [Related]

  • 17. Association of cytokine polymorphic inheritance and in vitro cytokine production in anti-CD3/CD28-stimulated peripheral blood lymphocytes.
    Hoffmann SC, Stanley EM, Darrin Cox E, Craighead N, DiMercurio BS, Koziol DE, Harlan DM, Kirk AD, Blair PJ.
    Transplantation; 2001 Oct 27; 72(8):1444-50. PubMed ID: 11685118
    [Abstract] [Full Text] [Related]

  • 18. Cyclosporine preserves the anergic state of human T cells induced by costimulation blockade in vitro.
    Koenen HJ, Fasse E, Joosten I.
    Transplantation; 2005 Aug 27; 80(4):522-9. PubMed ID: 16123728
    [Abstract] [Full Text] [Related]

  • 19. Tacrolimus and cyclosporine differ in their capacity to overcome ongoing allograft rejection as a result of their differential abilities to inhibit interleukin-10 production.
    Jiang H, Wynn C, Pan F, Ebbs A, Erickson LM, Kobayashi M.
    Transplantation; 2002 Jun 15; 73(11):1808-17. PubMed ID: 12085006
    [Abstract] [Full Text] [Related]

  • 20. Genetic association of interleukin-2, interleukin-4, interleukin-6, transforming growth factor-β, tumour necrosis factor-α and blood concentrations of calcineurin inhibitors in Turkish renal transplant patients.
    Seyhun Y, Ciftci HS, Kekik C, Karadeniz MS, Tefik T, Nane I, Turkmen A, Oguz FS, Aydin F.
    Int J Immunogenet; 2015 Jun 15; 42(3):147-60. PubMed ID: 25817300
    [Abstract] [Full Text] [Related]

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