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362 related items for PubMed ID: 12446738

  • 1. Attenuation of Helicobacter pylori CagA x SHP-2 signaling by interaction between CagA and C-terminal Src kinase.
    Tsutsumi R, Higashi H, Higuchi M, Okada M, Hatakeyama M.
    J Biol Chem; 2003 Feb 07; 278(6):3664-70. PubMed ID: 12446738
    [Abstract] [Full Text] [Related]

  • 2. Deregulation of SHP-2 tyrosine phosphatase by the Helicobacter pylori virulence factor CagA.
    Hatakeyama M.
    Keio J Med; 2002 Dec 07; 51 Suppl 2():26-32. PubMed ID: 12528933
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  • 3. Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation.
    Higashi H, Nakaya A, Tsutsumi R, Yokoyama K, Fujii Y, Ishikawa S, Higuchi M, Takahashi A, Kurashima Y, Teishikata Y, Tanaka S, Azuma T, Hatakeyama M.
    J Biol Chem; 2004 Apr 23; 279(17):17205-16. PubMed ID: 14963045
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  • 4. Focal adhesion kinase is a substrate and downstream effector of SHP-2 complexed with Helicobacter pylori CagA.
    Tsutsumi R, Takahashi A, Azuma T, Higashi H, Hatakeyama M.
    Mol Cell Biol; 2006 Jan 23; 26(1):261-76. PubMed ID: 16354697
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  • 5. Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites.
    Higashi H, Tsutsumi R, Fujita A, Yamazaki S, Asaka M, Azuma T, Hatakeyama M.
    Proc Natl Acad Sci U S A; 2002 Oct 29; 99(22):14428-33. PubMed ID: 12391297
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  • 6. Influence of EPIYA-repeat polymorphism on the phosphorylation-dependent biological activity of Helicobacter pylori CagA.
    Naito M, Yamazaki T, Tsutsumi R, Higashi H, Onoe K, Yamazaki S, Azuma T, Hatakeyama M.
    Gastroenterology; 2006 Apr 29; 130(4):1181-90. PubMed ID: 16618412
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  • 10. The CagA protein of Helicobacter pylori is translocated into epithelial cells and binds to SHP-2 in human gastric mucosa.
    Yamazaki S, Yamakawa A, Ito Y, Ohtani M, Higashi H, Hatakeyama M, Azuma T.
    J Infect Dis; 2003 Jan 15; 187(2):334-7. PubMed ID: 12552462
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  • 12. c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains.
    Mueller D, Tegtmeyer N, Brandt S, Yamaoka Y, De Poire E, Sgouras D, Wessler S, Torres J, Smolka A, Backert S.
    J Clin Invest; 2012 Apr 15; 122(4):1553-66. PubMed ID: 22378042
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  • 13. The role of Helicobacter pylori CagA in gastric carcinogenesis.
    Hatakeyama M.
    Int J Hematol; 2006 Nov 15; 84(4):301-8. PubMed ID: 17118755
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  • 14. Helicobacter pylori CagA oncoprotein interacts with SHIP2 to increase its delivery into gastric epithelial cells.
    Fujii Y, Murata-Kamiya N, Hatakeyama M.
    Cancer Sci; 2020 May 15; 111(5):1596-1606. PubMed ID: 32198795
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  • 15. Helicobacter pylori CagA -- a bacterial intruder conspiring gastric carcinogenesis.
    Hatakeyama M.
    Int J Cancer; 2006 Sep 15; 119(6):1217-23. PubMed ID: 16557568
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  • 16. The Helicobacter pylori CagA protein induces cortactin dephosphorylation and actin rearrangement by c-Src inactivation.
    Selbach M, Moese S, Hurwitz R, Hauck CR, Meyer TF, Backert S.
    EMBO J; 2003 Feb 03; 22(3):515-28. PubMed ID: 12554652
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  • 17. Systematic analysis of phosphotyrosine antibodies recognizing single phosphorylated EPIYA-motifs in CagA of East Asian-type Helicobacter pylori strains.
    Lind J, Backert S, Hoffmann R, Eichler J, Yamaoka Y, Perez-Perez GI, Torres J, Sticht H, Tegtmeyer N.
    BMC Microbiol; 2016 Sep 02; 16(1):201. PubMed ID: 27590005
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  • 18. CagA Phosphorylation in Helicobacter pylori-Infected B Cells Is Mediated by the Nonreceptor Tyrosine Kinases of the Src and Abl Families.
    Krisch LM, Posselt G, Hammerl P, Wessler S.
    Infect Immun; 2016 Sep 02; 84(9):2671-80. PubMed ID: 27382024
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  • 19. Structural and functional diversity in the PAR1b/MARK2-binding region of Helicobacter pylori CagA.
    Lu HS, Saito Y, Umeda M, Murata-Kamiya N, Zhang HM, Higashi H, Hatakeyama M.
    Cancer Sci; 2008 Oct 02; 99(10):2004-11. PubMed ID: 19016760
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