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176 related items for PubMed ID: 12447877

  • 1. Epidermal growth factor-induced activation of the insulin-like growth factor I receptor in rat hepatocytes.
    Hallak H, Moehren G, Tang J, Kaou M, Addas M, Hoek JB, Rubin R.
    Hepatology; 2002 Dec; 36(6):1509-18. PubMed ID: 12447877
    [Abstract] [Full Text] [Related]

  • 2. Epidermal growth factor (EGF) receptor blockade inhibits the action of EGF, insulin-like growth factor I, and a protein kinase A activator on the mitogen-activated protein kinase pathway in prostate cancer cell lines.
    Putz T, Culig Z, Eder IE, Nessler-Menardi C, Bartsch G, Grunicke H, Uberall F, Klocker H.
    Cancer Res; 1999 Jan 01; 59(1):227-33. PubMed ID: 9892211
    [Abstract] [Full Text] [Related]

  • 3. Activation and glucagon regulation of mitogen-activated protein kinases (MAPK) by insulin and epidermal growth factor in cultured rat and human hepatocytes.
    Ulrich RG, Cramer CT, Adams LA, Kletzien RF.
    Cell Biochem Funct; 1998 Jun 01; 16(2):77-85. PubMed ID: 9636995
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of insulin-like growth factor-I signaling by ethanol in neuronal cells.
    Hallak H, Seiler AE, Green JS, Henderson A, Ross BN, Rubin R.
    Alcohol Clin Exp Res; 2001 Jul 01; 25(7):1058-64. PubMed ID: 11505033
    [Abstract] [Full Text] [Related]

  • 5. A role for Akt in epidermal growth factor-stimulated cell cycle progression in cultured hepatocytes: generation of a hyperproliferative window after adenoviral expression of constitutively active Akt.
    Luo Y, Dixon CJ, Hall JF, White PJ, Boarder MR.
    J Pharmacol Exp Ther; 2007 Jun 01; 321(3):884-91. PubMed ID: 17371807
    [Abstract] [Full Text] [Related]

  • 6. Epidermal growth factor induces insulin receptor substrate-2 in breast cancer cells via c-Jun NH(2)-terminal kinase/activator protein-1 signaling to regulate cell migration.
    Cui X, Kim HJ, Kuiatse I, Kim H, Brown PH, Lee AV.
    Cancer Res; 2006 May 15; 66(10):5304-13. PubMed ID: 16707456
    [Abstract] [Full Text] [Related]

  • 7. Insulin-like growth factor-I (IGF-I) induces epidermal growth factor receptor transactivation and cell proliferation through reactive oxygen species.
    Meng D, Shi X, Jiang BH, Fang J.
    Free Radic Biol Med; 2007 Jun 01; 42(11):1651-60. PubMed ID: 17462533
    [Abstract] [Full Text] [Related]

  • 8. EGF receptor-mediated, c-Src-dependent, activation of Stat5b is downregulated in mitogenically responsive hepatocytes.
    Guren TK, Ødegård J, Abrahamsen H, Thoresen GH, Susa M, Andersson Y, Østby E, Christoffersen T.
    J Cell Physiol; 2003 Jul 01; 196(1):113-23. PubMed ID: 12767047
    [Abstract] [Full Text] [Related]

  • 9. Effects of insulin-like growth factor (IGF) binding protein-3 (IGFBP-3) on endometrial cancer (HHUA) cell apoptosis and EGF stimulated cell proliferation in vitro.
    Mochizuki T, Sakai K, Iwashita M.
    Growth Horm IGF Res; 2006 Jun 01; 16(3):202-10. PubMed ID: 16844395
    [Abstract] [Full Text] [Related]

  • 10. Intracellular transactivation of the insulin-like growth factor I receptor by an epidermal growth factor receptor.
    Burgaud JL, Baserga R.
    Exp Cell Res; 1996 Mar 15; 223(2):412-9. PubMed ID: 8601418
    [Abstract] [Full Text] [Related]

  • 11. Insulin receptor substrate-4 signaling in quiescent rat hepatocytes and in regenerating rat liver.
    Escribano O, Fernández-Moreno MD, Zueco JA, Menor C, Fueyo J, Ropero RM, Diaz-Laviada I, Román ID, Guijarro LG.
    Hepatology; 2003 Jun 15; 37(6):1461-9. PubMed ID: 12774026
    [Abstract] [Full Text] [Related]

  • 12. Epidermal growth factor treatment switches δ-opioid receptor-stimulated extracellular signal-regulated kinases 1 and 2 signaling from an epidermal growth factor to an insulin-like growth factor-1 receptor-dependent mechanism.
    Eisinger DA, Ammer H.
    Mol Pharmacol; 2011 Feb 15; 79(2):326-35. PubMed ID: 21078885
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulin-like growth factor receptor mRNA involves inactivation of ErbBs, PI-3K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone receptor activity.
    Salatino M, Schillaci R, Proietti CJ, Carnevale R, Frahm I, Molinolo AA, Iribarren A, Charreau EH, Elizalde PV.
    Oncogene; 2004 Jul 01; 23(30):5161-74. PubMed ID: 15122317
    [Abstract] [Full Text] [Related]

  • 14. Neutral endopeptidase inhibits neuropeptide-mediated transactivation of the insulin-like growth factor receptor-Akt cell survival pathway.
    Sumitomo M, Milowsky MI, Shen R, Navarro D, Dai J, Asano T, Hayakawa M, Nanus DM.
    Cancer Res; 2001 Apr 15; 61(8):3294-8. PubMed ID: 11309283
    [Abstract] [Full Text] [Related]

  • 15. Src tyrosine kinase inhibitor PP2 suppresses ERK1/2 activation and epidermal growth factor receptor transactivation by X-irradiation.
    Li Z, Hosoi Y, Cai K, Tanno Y, Matsumoto Y, Enomoto A, Morita A, Nakagawa K, Miyagawa K.
    Biochem Biophys Res Commun; 2006 Mar 10; 341(2):363-8. PubMed ID: 16414009
    [Abstract] [Full Text] [Related]

  • 16. The emergence of ErbB2 expression in cultured rat hepatocytes correlates with enhanced and diversified EGF-mediated signaling.
    Scheving LA, Zhang L, Stevenson MC, Kwak ES, Russell WE.
    Am J Physiol Gastrointest Liver Physiol; 2006 Jul 10; 291(1):G16-25. PubMed ID: 16769812
    [Abstract] [Full Text] [Related]

  • 17. Insulin-like growth factor receptor as a therapeutic target in head and neck cancer.
    Barnes CJ, Ohshiro K, Rayala SK, El-Naggar AK, Kumar R.
    Clin Cancer Res; 2007 Jul 15; 13(14):4291-9. PubMed ID: 17634559
    [Abstract] [Full Text] [Related]

  • 18. The protein kinase C inhibitor Go6976 [12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3,4-c)-carbazole] potentiates agonist-induced mitogen-activated protein kinase activation through tyrosine phosphorylation of the epidermal growth factor receptor.
    Shah BH, Olivares-Reyes JA, Catt KJ.
    Mol Pharmacol; 2005 Jan 15; 67(1):184-94. PubMed ID: 15465928
    [Abstract] [Full Text] [Related]

  • 19. A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.
    Burtrum D, Zhu Z, Lu D, Anderson DM, Prewett M, Pereira DS, Bassi R, Abdullah R, Hooper AT, Koo H, Jimenez X, Johnson D, Apblett R, Kussie P, Bohlen P, Witte L, Hicklin DJ, Ludwig DL.
    Cancer Res; 2003 Dec 15; 63(24):8912-21. PubMed ID: 14695208
    [Abstract] [Full Text] [Related]

  • 20. c-myb stimulates cell growth by regulation of insulin-like growth factor (IGF) and IGF-binding protein-3 in K562 leukemia cells.
    Kim MS, Kim SY, Arunachalam S, Hwang PH, Yi HK, Nam SY, Lee DY.
    Biochem Biophys Res Commun; 2009 Jul 17; 385(1):38-43. PubMed ID: 19427836
    [Abstract] [Full Text] [Related]


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