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166 related items for PubMed ID: 12450581

  • 1. Albutropin: a growth hormone-albumin fusion with improved pharmacokinetics and pharmacodynamics in rats and monkeys.
    Osborn BL, Sekut L, Corcoran M, Poortman C, Sturm B, Chen G, Mather D, Lin HL, Parry TJ.
    Eur J Pharmacol; 2002 Dec 05; 456(1-3):149-58. PubMed ID: 12450581
    [Abstract] [Full Text] [Related]

  • 2. Testosterone stimulates growth of tibial epiphyseal growth plate and insulin-like growth factor-1 receptor abundance in hypophysectomized and castrated rats.
    Phillip M, Maor G, Assa S, Silbergeld A, Segev Y.
    Endocrine; 2001 Oct 05; 16(1):1-6. PubMed ID: 11822821
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  • 3. Nonclinical pharmacokinetic and pharmacodynamic characterisation of somapacitan: A reversible non-covalent albumin-binding growth hormone.
    Thygesen P, Andersen HS, Behrens C, Fels JJ, Nørskov-Lauritsen L, Rischel C, Johansen NL.
    Growth Horm IGF Res; 2017 Aug 05; 35():8-16. PubMed ID: 28595133
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  • 4. Designing a long-acting human growth hormone (hGH) by fusing the carboxyl-terminal peptide of human chorionic gonadotropin beta-subunit to the coding sequence of hGH.
    Fares F, Guy R, Bar-Ilan A, Felikman Y, Fima E.
    Endocrinology; 2010 Sep 05; 151(9):4410-7. PubMed ID: 20660071
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  • 5. Histologic evidence: growth hormone completely prevents reduction in cortical bone gain and partially prevents cancellous osteopenia in the tibia of hypophysectomized rats.
    Chen MM, Yeh JK, Aloia JF.
    Anat Rec; 1997 Oct 05; 249(2):163-72. PubMed ID: 9335461
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  • 7. Recombinant human growth hormone (GH)-binding protein enhances the growth-promoting activity of human GH in the rat.
    Clark RG, Mortensen DL, Carlsson LM, Spencer SA, McKay P, Mulkerrin M, Moore J, Cunningham BC.
    Endocrinology; 1996 Oct 05; 137(10):4308-15. PubMed ID: 8828490
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  • 8. Albugranin, a recombinant human granulocyte colony stimulating factor (G-CSF) genetically fused to recombinant human albumin induces prolonged myelopoietic effects in mice and monkeys.
    Halpern W, Riccobene TA, Agostini H, Baker K, Stolow D, Gu ML, Hirsch J, Mahoney A, Carrell J, Boyd E, Grzegorzewski KJ.
    Pharm Res; 2002 Nov 05; 19(11):1720-9. PubMed ID: 12458679
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  • 9. Alterations of growth plate and abnormal insulin-like growth factor I metabolism in growth-retarded hypokalemic rats: effect of growth hormone treatment.
    Gil-Peña H, Garcia-Lopez E, Alvarez-Garcia O, Loredo V, Carbajo-Perez E, Ordoñez FA, Rodriguez-Suarez J, Santos F.
    Am J Physiol Renal Physiol; 2009 Sep 05; 297(3):F639-45. PubMed ID: 19587145
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  • 10. In Vitro and in Vivo Characterization of MOD-4023, a Long-Acting Carboxy-Terminal Peptide (CTP)-Modified Human Growth Hormone.
    Hershkovitz O, Bar-Ilan A, Guy R, Felikman Y, Moschcovich L, Hwa V, Rosenfeld RG, Fima E, Hart G.
    Mol Pharm; 2016 Feb 01; 13(2):631-9. PubMed ID: 26713839
    [Abstract] [Full Text] [Related]

  • 11. Local injections of human or rat growth hormone or of purified human somatomedin-C stimulate unilateral tibial epiphyseal growth in hypophysectomized rats.
    Russell SM, Spencer EM.
    Endocrinology; 1985 Jun 01; 116(6):2563-7. PubMed ID: 4039658
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  • 15. Pharmacokinetics and pharmacodynamics of GH: dependence on route and dosage of administration.
    Keller A, Wu Z, Kratzsch J, Keller E, Blum WF, Kniess A, Preiss R, Teichert J, Strasburger CJ, Bidlingmaier M.
    Eur J Endocrinol; 2007 Jun 01; 156(6):647-53. PubMed ID: 17535864
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  • 16. A long-acting, mono-PEGylated human growth hormone analog is a potent stimulator of weight gain and bone growth in hypophysectomized rats.
    Cox GN, Rosendahl MS, Chlipala EA, Smith DJ, Carlson SJ, Doherty DH.
    Endocrinology; 2007 Apr 01; 148(4):1590-7. PubMed ID: 17234711
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  • 17. Assessment of the Pharmacokinetics, Pharmacodynamics, and Safety of Single Doses of TV-1106, a Long-Acting Growth Hormone, in Healthy Japanese and Caucasian Subjects.
    Cohen-Barak O, Barkay H, Rasamoelisolo M, Butler K, Yamada K, Bassan M, Yoon E, Spiegelstein O.
    Clin Pharmacol Drug Dev; 2017 Jul 01; 6(4):331-342. PubMed ID: 27489211
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  • 18. Effect of growth hormone and insulin-like growth factor I (IGF-I) on the expression of IGF-I messenger ribonucleic acid and peptide in rat tibial growth plate and articular chondrocytes in vivo.
    Reinecke M, Schmid AC, Heyberger-Meyer B, Hunziker EB, Zapf J.
    Endocrinology; 2000 Aug 01; 141(8):2847-53. PubMed ID: 10919271
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  • 19. Upper airway loading induces growth retardation and change in local chondrocyte IGF-I expression is reversed by stimulation of GH release in juvenile rats.
    Segev Y, Berdugo-Boura N, Porati O, Tarasiuk A.
    J Appl Physiol (1985); 2008 Nov 01; 105(5):1602-9. PubMed ID: 18787088
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  • 20. The effect of polyethylene glycol recombinant human growth hormone on growth and glucose metabolism in hypophysectomized rats.
    Zhang ZX, Liu YK, Pan H, Pan L, Zhang Q, Su HM, Zhao QL, Li H, He C.
    Growth Horm IGF Res; 2012 Feb 01; 22(1):30-5. PubMed ID: 22257554
    [Abstract] [Full Text] [Related]

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