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400 related items for PubMed ID: 12456794

  • 1. Yoked complexes of human choriogonadotropin and the lutropin receptor: evidence that monomeric individual subunits are inactive.
    Narayan P, Gray J, Puett D.
    Mol Endocrinol; 2002 Dec; 16(12):2733-45. PubMed ID: 12456794
    [Abstract] [Full Text] [Related]

  • 2. Specificity of cognate ligand-receptor interactions: fusion proteins of human chorionic gonadotropin and the heptahelical receptors for human luteinizing hormone, thyroid-stimulating hormone, and follicle-stimulating hormone.
    Schubert RL, Narayan P, Puett D.
    Endocrinology; 2003 Jan; 144(1):129-37. PubMed ID: 12488338
    [Abstract] [Full Text] [Related]

  • 3. Fusing the carboxy-terminal peptide of the chorionic gonadotropin (CG) beta-subunit to the common alpha-subunit: retention of O-linked glycosylation and enhanced in vivo bioactivity of chimeric human CG.
    Furuhashi M, Shikone T, Fares FA, Sugahara T, Hsueh AJ, Boime I.
    Mol Endocrinol; 1995 Jan; 9(1):54-63. PubMed ID: 7539107
    [Abstract] [Full Text] [Related]

  • 4. Genetic fusion of an alpha-subunit gene to the follicle-stimulating hormone and chorionic gonadotropin-beta subunit genes: production of a bifunctional protein.
    Kanda M, Jablonka-Shariff A, Sato A, Pixley MR, Bos E, Hiro'oka T, Ben-Menahem D, Boime I.
    Mol Endocrinol; 1999 Nov; 13(11):1873-81. PubMed ID: 10551781
    [Abstract] [Full Text] [Related]

  • 5. Functional role of transmembrane helix 7 in the activation of the heptahelical lutropin receptor.
    Angelova K, Narayan P, Simon JP, Puett D.
    Mol Endocrinol; 2000 Apr; 14(4):459-71. PubMed ID: 10770485
    [Abstract] [Full Text] [Related]

  • 6. Overexpression of human chorionic gonadotropin causes multiple reproductive defects in transgenic mice.
    Matzuk MM, DeMayo FJ, Hadsell LA, Kumar TR.
    Biol Reprod; 2003 Jul; 69(1):338-46. PubMed ID: 12672665
    [Abstract] [Full Text] [Related]

  • 7. A biologically active single chain human chorionic gonadotropin analog with altered receptor binding properties.
    Narayan P, Gray J, Puett D.
    Endocrinology; 2000 Jan; 141(1):67-71. PubMed ID: 10614624
    [Abstract] [Full Text] [Related]

  • 8. Characterization of a region of the lutropin receptor extracellular domain near transmembrane helix 1 that is important in ligand-mediated signaling.
    Alvarez CA, Narayan P, Huang J, Puett D.
    Endocrinology; 1999 Apr; 140(4):1775-82. PubMed ID: 10098515
    [Abstract] [Full Text] [Related]

  • 9. Effect of individual N-glycosyl chains in the beta-subunit on the conformation of human choriogonadotropin.
    Shao K, Balasubramanian SV, Pope CM, Bahl OP.
    Mol Cell Endocrinol; 1998 Nov 25; 146(1-2):39-48. PubMed ID: 10022761
    [Abstract] [Full Text] [Related]

  • 10. Single-chain human chorionic gonadotropin analogs containing the determinant loop of the beta-subunit linked to the alpha-subunit.
    Schubert RL, Puett D.
    J Mol Endocrinol; 2003 Aug 25; 31(1):157-68. PubMed ID: 12914533
    [Abstract] [Full Text] [Related]

  • 11. Effect of modification of all loop regions in the alpha- and beta-subunits of human choriogonadotropin on its signal transduction activity.
    Shao K, Purohit S, Bahl OP.
    Mol Cell Endocrinol; 1996 Sep 18; 122(2):173-82. PubMed ID: 8902847
    [Abstract] [Full Text] [Related]

  • 12. Expression and characterization of recombinant beta-subunit hCG homodimer.
    Lobel L, Pollak S, Wang S, Chaney M, Lustbader JW.
    Endocrine; 1999 Jun 18; 10(3):261-70. PubMed ID: 10484290
    [Abstract] [Full Text] [Related]

  • 13. Nonassembled human chorionic gonadotropin subunits and alphaalpha-homodimers use fast-track processing in the secretory pathway in contrast to alphabeta-heterodimers.
    Merz WE, Krause JM, Roig J, Singh V, Berger P.
    Endocrinology; 2007 Dec 18; 148(12):5831-41. PubMed ID: 17761764
    [Abstract] [Full Text] [Related]

  • 14. Lys91 and His90 of the alpha-subunit are crucial for receptor binding and hormone action of follicle-stimulating hormone (FSH) and play hormone-specific roles in FSH and human chorionic gonadotropin.
    Zeng H, Ji I, Ji TH.
    Endocrinology; 1995 Jul 18; 136(7):2948-53. PubMed ID: 7540545
    [Abstract] [Full Text] [Related]

  • 15. Intracellular retention of mutant gonadotropin receptors results in loss of hormone binding activity of the follitropin receptor but not of the lutropin/choriogonadotropin receptor.
    Rozzell TG, Wang H, Liu X, Segaloff DL.
    Mol Endocrinol; 1995 Dec 18; 9(12):1727-36. PubMed ID: 8614409
    [Abstract] [Full Text] [Related]

  • 16. The biological action of choriogonadotropin is not dependent on the complete native quaternary interactions between the subunits.
    Jackson AM, Berger P, Pixley M, Klein C, Hsueh AJ, Boime I.
    Mol Endocrinol; 1999 Dec 18; 13(12):2175-88. PubMed ID: 10598590
    [Abstract] [Full Text] [Related]

  • 17. Mutagenesis of cysteine residues in the human gonadotropin alpha subunit. Roles of individual disulfide bonds in secretion, assembly, and biologic activity.
    Furuhashi M, Ando H, Bielinska M, Pixley MR, Shikone T, Hsueh AJ, Boime I.
    J Biol Chem; 1994 Oct 14; 269(41):25543-8. PubMed ID: 7929256
    [Abstract] [Full Text] [Related]

  • 18. Deglycosylated human chorionic gonadotropin (hCG) antagonizes hCG stimulation of 3',5'-cyclic adenosine monophosphate accumulation through a noncompetitive interaction with recombinant human luteinizing hormone receptors.
    Dunkel L, Jia XC, Nishimori K, Boime I, Hsueh AJ.
    Endocrinology; 1993 Feb 14; 132(2):763-9. PubMed ID: 8381073
    [Abstract] [Full Text] [Related]

  • 19. Expression of a recombinant bifunctional protein from a chimera of human lutropin receptor and human chorionic gonadotropin beta-subunit.
    Hao M, Rathnam P, Saxena B.
    J Reprod Immunol; 2004 Oct 14; 63(2):123-35. PubMed ID: 15380943
    [Abstract] [Full Text] [Related]

  • 20. Site-directed mutagenesis of amino acids 33-44 of the common alpha-subunit reveals different structural requirements for heterodimer expression among the glycoprotein hormones and suggests that cyclic adenosine 3',5'-monophosphate production and growth promotion are potentially dissociable functions of human thyrotropin.
    Grossmann M, Szkudlinski MW, Dias JA, Xia H, Wong R, Puett D, Weintraub BD.
    Mol Endocrinol; 1996 Jun 14; 10(6):769-79. PubMed ID: 8776737
    [Abstract] [Full Text] [Related]

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