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366 related items for PubMed ID: 12459440

  • 1. Two-step error-prone bypass of the (+)- and (-)-trans-anti-BPDE-N2-dG adducts by human DNA polymerases eta and kappa.
    Zhang Y, Wu X, Guo D, Rechkoblit O, Geacintov NE, Wang Z.
    Mutat Res; 2002 Dec 29; 510(1-2):23-35. PubMed ID: 12459440
    [Abstract] [Full Text] [Related]

  • 2. Poleta, Polzeta and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells.
    Zhao B, Wang J, Geacintov NE, Wang Z.
    Nucleic Acids Res; 2006 Dec 29; 34(2):417-25. PubMed ID: 16415180
    [Abstract] [Full Text] [Related]

  • 3. Activities of human DNA polymerase kappa in response to the major benzo[a]pyrene DNA adduct: error-free lesion bypass and extension synthesis from opposite the lesion.
    Zhang Y, Wu X, Guo D, Rechkoblit O, Wang Z.
    DNA Repair (Amst); 2002 Jul 17; 1(7):559-69. PubMed ID: 12509229
    [Abstract] [Full Text] [Related]

  • 4. Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene).
    Suzuki N, Ohashi E, Kolbanovskiy A, Geacintov NE, Grollman AP, Ohmori H, Shibutani S.
    Biochemistry; 2002 May 14; 41(19):6100-6. PubMed ID: 11994005
    [Abstract] [Full Text] [Related]

  • 5. trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases.
    Rechkoblit O, Zhang Y, Guo D, Wang Z, Amin S, Krzeminsky J, Louneva N, Geacintov NE.
    J Biol Chem; 2002 Aug 23; 277(34):30488-94. PubMed ID: 12063247
    [Abstract] [Full Text] [Related]

  • 6. Base pair conformation-dependent excision of benzo[a]pyrene diol epoxide-guanine adducts by human nucleotide excision repair enzymes.
    Hess MT, Gunz D, Luneva N, Geacintov NE, Naegeli H.
    Mol Cell Biol; 1997 Dec 23; 17(12):7069-76. PubMed ID: 9372938
    [Abstract] [Full Text] [Related]

  • 7. Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[a]pyrene-guanine adducts by human DNA polymerase kappa.
    Sassa A, Niimi N, Fujimoto H, Katafuchi A, Grúz P, Yasui M, Gupta RC, Johnson F, Ohta T, Nohmi T.
    Mutat Res; 2011 Jan 10; 718(1-2):10-7. PubMed ID: 21078407
    [Abstract] [Full Text] [Related]

  • 8. Effects of the N terminus of mouse DNA polymerase κ on the bypass of a guanine-benzo[a]pyrenyl adduct.
    Liu Y, Ma X, Guo C.
    J Biochem; 2016 Apr 10; 159(4):471-9. PubMed ID: 26634445
    [Abstract] [Full Text] [Related]

  • 9. Mutagenesis of benzo[a]pyrene diol epoxide in yeast: requirement for DNA polymerase zeta and involvement of DNA polymerase eta.
    Xie Z, Braithwaite E, Guo D, Zhao B, Geacintov NE, Wang Z.
    Biochemistry; 2003 Sep 30; 42(38):11253-62. PubMed ID: 14503875
    [Abstract] [Full Text] [Related]

  • 10. Extending the understanding of mutagenicity: structural insights into primer-extension past a benzo[a]pyrene diol epoxide-DNA adduct.
    Perlow RA, Broyde S.
    J Mol Biol; 2003 Apr 04; 327(4):797-818. PubMed ID: 12654264
    [Abstract] [Full Text] [Related]

  • 11. Human DNA polymerases catalyze lesion bypass across benzo[a]pyrene-derived DNA adduct clustered with an abasic site.
    Starostenko LV, Rechkunova NI, Lebedeva NA, Kolbanovskiy A, Geacintov NE, Lavrik OI.
    DNA Repair (Amst); 2014 Dec 04; 24():1-9. PubMed ID: 25460917
    [Abstract] [Full Text] [Related]

  • 12. Effects of base sequence context on translesion synthesis past a bulky (+)-trans-anti-B[a]P-N2-dG lesion catalyzed by the Y-family polymerase pol kappa.
    Huang X, Kolbanovskiy A, Wu X, Zhang Y, Wang Z, Zhuang P, Amin S, Geacintov NE.
    Biochemistry; 2003 Mar 04; 42(8):2456-66. PubMed ID: 12600213
    [Abstract] [Full Text] [Related]

  • 13. In vivo evidence that phenylalanine 171 acts as a molecular brake for translesion DNA synthesis across benzo[a]pyrene DNA adducts by human DNA polymerase κ.
    Sassa A, Suzuki T, Kanemaru Y, Niimi N, Fujimoto H, Katafuchi A, Grúz P, Yasui M, Gupta RC, Johnson F, Ohta T, Honma M, Adachi N, Nohmi T.
    DNA Repair (Amst); 2014 Mar 04; 15():21-8. PubMed ID: 24461735
    [Abstract] [Full Text] [Related]

  • 14. Fidelity of translesional synthesis past benzo[a]pyrene diol epoxide-2'-deoxyguanosine DNA adducts: marked effects of host cell, sequence context, and chirality.
    Moriya M, Spiegel S, Fernandes A, Amin S, Liu T, Geacintov N, Grollman AP.
    Biochemistry; 1996 Dec 24; 35(51):16646-51. PubMed ID: 8988000
    [Abstract] [Full Text] [Related]

  • 15. Mutagenic potential of benzo[a]pyrene-derived DNA adducts positioned in codon 273 of the human P53 gene.
    Dong H, Bonala RR, Suzuki N, Johnson F, Grollman AP, Shibutani S.
    Biochemistry; 2004 Dec 21; 43(50):15922-8. PubMed ID: 15595848
    [Abstract] [Full Text] [Related]

  • 16. Spectral differentiation and immunoaffinity capillary electrophoresis separation of enantiomeric benzo(a)pyrene diol epoxide-derived DNA adducts.
    Miksa B, Chinnappan R, Dang NC, Reppert M, Matter B, Tretyakova N, Grubor NM, Jankowiak R.
    Chem Res Toxicol; 2007 Aug 21; 20(8):1192-9. PubMed ID: 17630708
    [Abstract] [Full Text] [Related]

  • 17. Translesional synthesis on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene).
    Shibutani S, Margulis LA, Geacintov NE, Grollman AP.
    Biochemistry; 1993 Jul 27; 32(29):7531-41. PubMed ID: 8338850
    [Abstract] [Full Text] [Related]

  • 18. DNA adducts from a tumorigenic metabolite of benzo[a]pyrene block human RNA polymerase II elongation in a sequence- and stereochemistry-dependent manner.
    Perlow RA, Kolbanovskii A, Hingerty BE, Geacintov NE, Broyde S, Scicchitano DA.
    J Mol Biol; 2002 Aug 02; 321(1):29-47. PubMed ID: 12139931
    [Abstract] [Full Text] [Related]

  • 19. Evading the proofreading machinery of a replicative DNA polymerase: induction of a mutation by an environmental carcinogen.
    Perlow RA, Broyde S.
    J Mol Biol; 2001 Jun 01; 309(2):519-36. PubMed ID: 11371169
    [Abstract] [Full Text] [Related]

  • 20. Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro.
    Zhang Y, Yuan F, Wu X, Wang M, Rechkoblit O, Taylor JS, Geacintov NE, Wang Z.
    Nucleic Acids Res; 2000 Nov 01; 28(21):4138-46. PubMed ID: 11058110
    [Abstract] [Full Text] [Related]

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