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Journal Abstract Search

236 related items for PubMed ID: 12460542

  • 21. Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein.
    Herms J, Schneider I, Dewachter I, Caluwaerts N, Kretzschmar H, Van Leuven F.
    J Biol Chem; 2003 Jan 24; 278(4):2484-9. PubMed ID: 12431992
    [Abstract] [Full Text] [Related]

  • 22. Secreted beta-amyloid precursor protein counteracts the proapoptotic action of mutant presenilin-1 by activation of NF-kappaB and stabilization of calcium homeostasis.
    Guo Q, Robinson N, Mattson MP.
    J Biol Chem; 1998 May 15; 273(20):12341-51. PubMed ID: 9575187
    [Abstract] [Full Text] [Related]

  • 23. Serum-withdrawal-dependent apoptosis of hippocampal neuroblasts involves Ca++ release by endoplasmic reticulum and caspase-12 activation.
    Voccoli V, Mazzoni F, Garcia-Gil M, Colombaioni L.
    Brain Res; 2007 May 25; 1147():1-11. PubMed ID: 17399692
    [Abstract] [Full Text] [Related]

  • 24. Herp stabilizes neuronal Ca2+ homeostasis and mitochondrial function during endoplasmic reticulum stress.
    Chan SL, Fu W, Zhang P, Cheng A, Lee J, Kokame K, Mattson MP.
    J Biol Chem; 2004 Jul 02; 279(27):28733-43. PubMed ID: 15102845
    [Abstract] [Full Text] [Related]

  • 25. Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice.
    Guo Q, Fu W, Sopher BL, Miller MW, Ware CB, Martin GM, Mattson MP.
    Nat Med; 1999 Jan 02; 5(1):101-6. PubMed ID: 9883847
    [Abstract] [Full Text] [Related]

  • 26. G206D Mutation of Presenilin-1 Reduces Pen2 Interaction, Increases Aβ42/Aβ40 Ratio and Elevates ER Ca(2+) Accumulation.
    Chen WT, Hsieh YF, Huang YJ, Lin CC, Lin YT, Liu YC, Lien CC, Cheng IH.
    Mol Neurobiol; 2015 Dec 02; 52(3):1835-1849. PubMed ID: 25394380
    [Abstract] [Full Text] [Related]

  • 27. Presenilin 1 Regulates [Ca2+]i and Mitochondria/ER Interaction in Cultured Rat Hippocampal Neurons.
    Korkotian E, Meshcheriakova A, Segal M.
    Oxid Med Cell Longev; 2019 Dec 02; 2019():7284967. PubMed ID: 31467635
    [Abstract] [Full Text] [Related]

  • 28. Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis.
    Sepulveda-Falla D, Barrera-Ocampo A, Hagel C, Korwitz A, Vinueza-Veloz MF, Zhou K, Schonewille M, Zhou H, Velazquez-Perez L, Rodriguez-Labrada R, Villegas A, Ferrer I, Lopera F, Langer T, De Zeeuw CI, Glatzel M.
    J Clin Invest; 2014 Apr 02; 124(4):1552-67. PubMed ID: 24569455
    [Abstract] [Full Text] [Related]

  • 29. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response.
    Katayama T, Imaizumi K, Sato N, Miyoshi K, Kudo T, Hitomi J, Morihara T, Yoneda T, Gomi F, Mori Y, Nakano Y, Takeda J, Tsuda T, Itoyama Y, Murayama O, Takashima A, St George-Hyslop P, Takeda M, Tohyama M.
    Nat Cell Biol; 1999 Dec 02; 1(8):479-85. PubMed ID: 10587643
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  • 31. Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels.
    Zatti G, Burgo A, Giacomello M, Barbiero L, Ghidoni R, Sinigaglia G, Florean C, Bagnoli S, Binetti G, Sorbi S, Pizzo P, Fasolato C.
    Cell Calcium; 2006 Jun 02; 39(6):539-50. PubMed ID: 16620965
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  • 33. Hypoxia-triggered m-calpain activation evokes endoplasmic reticulum stress and neuropathogenesis in a transgenic mouse model of Alzheimer's disease.
    Wang CY, Xie JW, Wang T, Xu Y, Cai JH, Wang X, Zhao BL, An L, Wang ZY.
    CNS Neurosci Ther; 2013 Oct 02; 19(10):820-33. PubMed ID: 23889979
    [Abstract] [Full Text] [Related]

  • 34. Susceptibility to cellular stress in PS1 mutant N2a cells is associated with mitochondrial defects and altered calcium homeostasis.
    Rojas-Charry L, Calero-Martinez S, Morganti C, Morciano G, Park K, Hagel C, Marciniak SJ, Glatzel M, Pinton P, Sepulveda-Falla D.
    Sci Rep; 2020 Apr 15; 10(1):6455. PubMed ID: 32296078
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  • 36. NF-kappaB activated by ER calcium release inhibits Abeta-mediated expression of CHOP protein: enhancement by AD-linked mutant presenilin 1.
    Schapansky J, Olson K, Van Der Ploeg R, Glazner G.
    Exp Neurol; 2007 Dec 15; 208(2):169-76. PubMed ID: 17927985
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  • 38. Mutant presenilin-1 induces apoptosis and downregulates Akt/PKB.
    Weihl CC, Ghadge GD, Kennedy SG, Hay N, Miller RJ, Roos RP.
    J Neurosci; 1999 Jul 01; 19(13):5360-9. PubMed ID: 10377346
    [Abstract] [Full Text] [Related]

  • 39. Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid beta-peptide.
    Guo Q, Furukawa K, Sopher BL, Pham DG, Xie J, Robinson N, Martin GM, Mattson MP.
    Neuroreport; 1996 Dec 20; 8(1):379-83. PubMed ID: 9051814
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