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298 related items for PubMed ID: 12463747

  • 1. Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase.
    Kicska GA, Tyler PC, Evans GB, Furneaux RH, Shi W, Fedorov A, Lewandowicz A, Cahill SM, Almo SC, Schramm VL.
    Biochemistry; 2002 Dec 10; 41(49):14489-98. PubMed ID: 12463747
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  • 4. Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis.
    Fedorov A, Shi W, Kicska G, Fedorov E, Tyler PC, Furneaux RH, Hanson JC, Gainsford GJ, Larese JZ, Schramm VL, Almo SC.
    Biochemistry; 2001 Jan 30; 40(4):853-60. PubMed ID: 11170405
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  • 5. Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces.
    Shi W, Basso LA, Santos DS, Tyler PC, Furneaux RH, Blanchard JS, Almo SC, Schramm VL.
    Biochemistry; 2001 Jul 27; 40(28):8204-15. PubMed ID: 11444966
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  • 7. Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases.
    Sauve AA, Cahill SM, Zech SG, Basso LA, Lewandowicz A, Santos DS, Grubmeyer C, Evans GB, Furneaux RH, Tyler PC, McDermott A, Girvin ME, Schramm VL.
    Biochemistry; 2003 May 20; 42(19):5694-705. PubMed ID: 12741826
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  • 9. Conformational states of human purine nucleoside phosphorylase at rest, at work, and with transition state analogues.
    Edwards AA, Tipton JD, Brenowitz MD, Emmett MR, Marshall AG, Evans GB, Tyler PC, Schramm VL.
    Biochemistry; 2010 Mar 09; 49(9):2058-67. PubMed ID: 20108972
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  • 10. Four generations of transition-state analogues for human purine nucleoside phosphorylase.
    Ho MC, Shi W, Rinaldo-Matthis A, Tyler PC, Evans GB, Clinch K, Almo SC, Schramm VL.
    Proc Natl Acad Sci U S A; 2010 Mar 16; 107(11):4805-12. PubMed ID: 20212140
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  • 11. Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase.
    Lewandowicz A, Tyler PC, Evans GB, Furneaux RH, Schramm VL.
    J Biol Chem; 2003 Aug 22; 278(34):31465-8. PubMed ID: 12842889
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  • 12. One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase.
    Miles RW, Tyler PC, Furneaux RH, Bagdassarian CK, Schramm VL.
    Biochemistry; 1998 Jun 16; 37(24):8615-21. PubMed ID: 9628722
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  • 13. Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function.
    Shi W, Ting LM, Kicska GA, Lewandowicz A, Tyler PC, Evans GB, Furneaux RH, Kim K, Almo SC, Schramm VL.
    J Biol Chem; 2004 Apr 30; 279(18):18103-6. PubMed ID: 14982926
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  • 14. Energetic mapping of transition state analogue interactions with human and Plasmodium falciparum purine nucleoside phosphorylases.
    Lewandowicz A, Ringia EA, Ting LM, Kim K, Tyler PC, Evans GB, Zubkova OV, Mee S, Painter GF, Lenz DH, Furneaux RH, Schramm VL.
    J Biol Chem; 2005 Aug 26; 280(34):30320-8. PubMed ID: 15961383
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  • 15. Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues.
    Rinaldo-Matthis A, Wing C, Ghanem M, Deng H, Wu P, Gupta A, Tyler PC, Evans GB, Furneaux RH, Almo SC, Wang CC, Schramm VL.
    Biochemistry; 2007 Jan 23; 46(3):659-68. PubMed ID: 17223688
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  • 16. L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase.
    Rinaldo-Matthis A, Murkin AS, Ramagopal UA, Clinch K, Mee SP, Evans GB, Tyler PC, Furneaux RH, Almo SC, Schramm VL.
    J Am Chem Soc; 2008 Jan 23; 130(3):842-4. PubMed ID: 18154341
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  • 17. Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase.
    Evans GB, Furneaux RH, Lewandowicz A, Schramm VL, Tyler PC.
    J Med Chem; 2003 Jul 17; 46(15):3412-23. PubMed ID: 12852771
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  • 18. Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition.
    Taylor EA, Rinaldo-Matthis A, Li L, Ghanem M, Hazleton KZ, Cassera MB, Almo SC, Schramm VL.
    Biochemistry; 2007 Oct 30; 46(43):12405-15. PubMed ID: 17918964
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  • 19. Inhibition and structure of Toxoplasma gondii purine nucleoside phosphorylase.
    Donaldson TM, Cassera MB, Ho MC, Zhan C, Merino EF, Evans GB, Tyler PC, Almo SC, Schramm VL, Kim K.
    Eukaryot Cell; 2014 May 30; 13(5):572-9. PubMed ID: 24585883
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  • 20. Intracellular rebinding of transition-state analogues provides extended in vivo inhibition lifetimes on human purine nucleoside phosphorylase.
    Gebre ST, Cameron SA, Li L, Babu YS, Schramm VL.
    J Biol Chem; 2017 Sep 22; 292(38):15907-15915. PubMed ID: 28794158
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