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Journal Abstract Search


244 related items for PubMed ID: 12464612

  • 1. Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure.
    Gotthardt M, Hammer RE, Hübner N, Monti J, Witt CC, McNabb M, Richardson JA, Granzier H, Labeit S, Herz J.
    J Biol Chem; 2003 Feb 21; 278(8):6059-65. PubMed ID: 12464612
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  • 3. M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere.
    Weinert S, Bergmann N, Luo X, Erdmann B, Gotthardt M.
    J Cell Biol; 2006 May 22; 173(4):559-70. PubMed ID: 16702235
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  • 4. Muscle atrophy in titin M-line deficient mice.
    Peng J, Raddatz K, Labeit S, Granzier H, Gotthardt M.
    J Muscle Res Cell Motil; 2005 May 22; 26(6-8):381-8. PubMed ID: 16470336
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  • 5. The NH2 terminus of titin spans the Z-disc: its interaction with a novel 19-kD ligand (T-cap) is required for sarcomeric integrity.
    Gregorio CC, Trombitás K, Centner T, Kolmerer B, Stier G, Kunke K, Suzuki K, Obermayr F, Herrmann B, Granzier H, Sorimachi H, Labeit S.
    J Cell Biol; 1998 Nov 16; 143(4):1013-27. PubMed ID: 9817758
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  • 8. Functional properties of the titin/connectin-associated proteins, the muscle-specific RING finger proteins (MURFs), in striated muscle.
    Gregorio CC, Perry CN, McElhinny AS.
    J Muscle Res Cell Motil; 2005 Nov 16; 26(6-8):389-400. PubMed ID: 16477476
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  • 9. Titins in C.elegans with unusual features: coiled-coil domains, novel regulation of kinase activity and two new possible elastic regions.
    Flaherty DB, Gernert KM, Shmeleva N, Tang X, Mercer KB, Borodovsky M, Benian GM.
    J Mol Biol; 2002 Oct 25; 323(3):533-49. PubMed ID: 12381307
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  • 10. A molecular map of the interactions between titin and myosin-binding protein C. Implications for sarcomeric assembly in familial hypertrophic cardiomyopathy.
    Freiburg A, Gautel M.
    Eur J Biochem; 1996 Jan 15; 235(1-2):317-23. PubMed ID: 8631348
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  • 11. Functional genomics of chicken, mouse, and human titin supports splice diversity as an important mechanism for regulating biomechanics of striated muscle.
    Granzier H, Radke M, Royal J, Wu Y, Irving TC, Gotthardt M, Labeit S.
    Am J Physiol Regul Integr Comp Physiol; 2007 Aug 15; 293(2):R557-67. PubMed ID: 17522126
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  • 12. Titin-thin filament interaction and potential role in muscle function.
    Jin JP.
    Adv Exp Med Biol; 2000 Aug 15; 481():319-33; discussion 334-5. PubMed ID: 10987081
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  • 13. Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy.
    Radke MH, Peng J, Wu Y, McNabb M, Nelson OL, Granzier H, Gotthardt M.
    Proc Natl Acad Sci U S A; 2007 Feb 27; 104(9):3444-9. PubMed ID: 17360664
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  • 16. Transient association of titin and myosin with microtubules in nascent myofibrils directed by the MURF2 RING-finger protein.
    Pizon V, Iakovenko A, Van Der Ven PF, Kelly R, Fatu C, Fürst DO, Karsenti E, Gautel M.
    J Cell Sci; 2002 Dec 01; 115(Pt 23):4469-82. PubMed ID: 12414993
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  • 17. Roles of titin in the structure and elasticity of the sarcomere.
    Tskhovrebova L, Trinick J.
    J Biomed Biotechnol; 2010 Dec 01; 2010():612482. PubMed ID: 20625501
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  • 18. The zebrafish runzel muscular dystrophy is linked to the titin gene.
    Steffen LS, Guyon JR, Vogel ED, Howell MH, Zhou Y, Weber GJ, Zon LI, Kunkel LM.
    Dev Biol; 2007 Sep 15; 309(2):180-92. PubMed ID: 17678642
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  • 19. Sense and stretchability: the role of titin and titin-associated proteins in myocardial stress-sensing and mechanical dysfunction.
    Linke WA.
    Cardiovasc Res; 2008 Mar 01; 77(4):637-48. PubMed ID: 17475230
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  • 20. Deleting Full Length Titin Versus the Titin M-Band Region Leads to Differential Mechanosignaling and Cardiac Phenotypes.
    Radke MH, Polack C, Methawasin M, Fink C, Granzier HL, Gotthardt M.
    Circulation; 2019 Apr 09; 139(15):1813-1827. PubMed ID: 30700140
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