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310 related items for PubMed ID: 12466971

  • 1. Loss of expression of death-inducing signaling complex (DISC) components in lung cancer cell lines and the influence of MYC amplification.
    Shivapurkar N, Reddy J, Matta H, Sathyanarayana UG, Huang CX, Toyooka S, Minna JD, Chaudhary PM, Gazdar AF.
    Oncogene; 2002 Dec 05; 21(55):8510-4. PubMed ID: 12466971
    [Abstract] [Full Text] [Related]

  • 2. TRAIL-R2 is not correlated with p53 status and is rarely mutated in non-small cell lung cancer.
    Wu WG, Soria JC, Wang L, Kemp BL, Mao L.
    Anticancer Res; 2000 Dec 05; 20(6B):4525-9. PubMed ID: 11205299
    [Abstract] [Full Text] [Related]

  • 3. Sensitivity of prostate cells to TRAIL-induced apoptosis increases with tumor progression: DR5 and caspase 8 are key players.
    Hesry V, Piquet-Pellorce C, Travert M, Donaghy L, Jégou B, Patard JJ, Guillaudeux T.
    Prostate; 2006 Jun 15; 66(9):987-95. PubMed ID: 16541419
    [Abstract] [Full Text] [Related]

  • 4. Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation.
    Hopkins-Donaldson S, Ziegler A, Kurtz S, Bigosch C, Kandioler D, Ludwig C, Zangemeister-Wittke U, Stahel R.
    Cell Death Differ; 2003 Mar 15; 10(3):356-64. PubMed ID: 12700635
    [Abstract] [Full Text] [Related]

  • 5. Expression and amplification of myc gene family in small cell lung cancer and its relation to biological characteristics.
    Takahashi T, Obata Y, Sekido Y, Hida T, Ueda R, Watanabe H, Ariyoshi Y, Sugiura T, Takahashi T.
    Cancer Res; 1989 May 15; 49(10):2683-8. PubMed ID: 2540905
    [Abstract] [Full Text] [Related]

  • 6. Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells.
    Liu X, Yue P, Zhou Z, Khuri FR, Sun SY.
    J Natl Cancer Inst; 2004 Dec 01; 96(23):1769-80. PubMed ID: 15572759
    [Abstract] [Full Text] [Related]

  • 7. Transition from SCLC to NSCLC phenotype is accompanied by an increased TRE-binding activity and recruitment of specific AP-1 proteins.
    Risse-Hackl G, Adamkiewicz J, Wimmel A, Schuermann M.
    Oncogene; 1998 Jun 11; 16(23):3057-68. PubMed ID: 9662339
    [Abstract] [Full Text] [Related]

  • 8. Differential inactivation of caspase-8 in lung cancers.
    Shivapurkar N, Toyooka S, Eby MT, Huang CX, Sathyanarayana UG, Cunningham HT, Reddy JL, Brambilla E, Takahashi T, Minna JD, Chaudhary PM, Gazdar AF.
    Cancer Biol Ther; 2002 Jun 11; 1(1):65-9. PubMed ID: 12170765
    [Abstract] [Full Text] [Related]

  • 9. Expression of DMBT1, a candidate tumor suppressor gene, is frequently lost in lung cancer.
    Wu W, Kemp BL, Proctor ML, Gazdar AF, Minna JD, Hong WK, Mao L.
    Cancer Res; 1999 Apr 15; 59(8):1846-51. PubMed ID: 10213490
    [Abstract] [Full Text] [Related]

  • 10. The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells.
    Liu X, Yue P, Chen S, Hu L, Lonial S, Khuri FR, Sun SY.
    Cancer Res; 2007 May 15; 67(10):4981-8. PubMed ID: 17510429
    [Abstract] [Full Text] [Related]

  • 11. Differences in expression of pro-caspases in small cell and non-small cell lung carcinoma.
    Joseph B, Ekedahl J, Sirzen F, Lewensohn R, Zhivotovsky B.
    Biochem Biophys Res Commun; 1999 Aug 27; 262(2):381-7. PubMed ID: 10462484
    [Abstract] [Full Text] [Related]

  • 12. Human retinoblastoma cells are resistant to apoptosis induced by death receptors: role of caspase-8 gene silencing.
    Poulaki V, Mitsiades CS, McMullan C, Fanourakis G, Negri J, Goudopoulou A, Halikias IX, Voutsinas G, Tseleni-Balafouta S, Miller JW, Mitsiades N.
    Invest Ophthalmol Vis Sci; 2005 Jan 27; 46(1):358-66. PubMed ID: 15623796
    [Abstract] [Full Text] [Related]

  • 13. Combined microarray analysis of small cell lung cancer reveals altered apoptotic balance and distinct expression signatures of MYC family gene amplification.
    Kim YH, Girard L, Giacomini CP, Wang P, Hernandez-Boussard T, Tibshirani R, Minna JD, Pollack JR.
    Oncogene; 2006 Jan 05; 25(1):130-8. PubMed ID: 16116477
    [Abstract] [Full Text] [Related]

  • 14. Influence of casein kinase II in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human rhabdomyosarcoma cells.
    Izeradjene K, Douglas L, Delaney A, Houghton JA.
    Clin Cancer Res; 2004 Oct 01; 10(19):6650-60. PubMed ID: 15475455
    [Abstract] [Full Text] [Related]

  • 15. Molecular genetics of small cell lung carcinoma.
    Wistuba II, Gazdar AF, Minna JD.
    Semin Oncol; 2001 Apr 01; 28(2 Suppl 4):3-13. PubMed ID: 11479891
    [Abstract] [Full Text] [Related]

  • 16. TRAIL resistance of breast cancer cells is associated with constitutive endocytosis of death receptors 4 and 5.
    Zhang Y, Zhang B.
    Mol Cancer Res; 2008 Dec 01; 6(12):1861-71. PubMed ID: 19074831
    [Abstract] [Full Text] [Related]

  • 17. Frequent and histological type-specific inactivation of 14-3-3sigma in human lung cancers.
    Osada H, Tatematsu Y, Yatabe Y, Nakagawa T, Konishi H, Harano T, Tezel E, Takada M, Takahashi T.
    Oncogene; 2002 Apr 04; 21(15):2418-24. PubMed ID: 11948426
    [Abstract] [Full Text] [Related]

  • 18. CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by dimethyl-celecoxib in human non small-cell lung cancer cells.
    Chen S, Liu X, Yue P, Schönthal AH, Khuri FR, Sun SY.
    Mol Pharmacol; 2007 Nov 04; 72(5):1269-79. PubMed ID: 17684158
    [Abstract] [Full Text] [Related]

  • 19. Unique resistance of breast carcinoma cell line T47D to TRAIL but not anti-Fas is linked to p43cFLIP(L).
    Guseva NV, Rokhlin OW, Taghiyev AF, Cohen MB.
    Breast Cancer Res Treat; 2008 Feb 04; 107(3):349-57. PubMed ID: 17453339
    [Abstract] [Full Text] [Related]

  • 20. Expression of p64c-myc and neuroendocrine properties define three subclasses of small cell lung cancer.
    Bepler G, Bading H, Heimann B, Kiefer P, Havemann K, Moelling K.
    Oncogene; 1989 Jan 04; 4(1):45-50. PubMed ID: 2536917
    [Abstract] [Full Text] [Related]


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