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Journal Abstract Search
726 related items for PubMed ID: 12467226
1. The effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumor-derived cell lines in vitro and in vivo. Rusnak DW, Lackey K, Affleck K, Wood ER, Alligood KJ, Rhodes N, Keith BR, Murray DM, Knight WB, Mullin RJ, Gilmer TM. Mol Cancer Ther; 2001 Dec; 1(2):85-94. PubMed ID: 12467226 [Abstract] [Full Text] [Related]
2. The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: potential therapy for cancer. Rusnak DW, Affleck K, Cockerill SG, Stubberfield C, Harris R, Page M, Smith KJ, Guntrip SB, Carter MC, Shaw RJ, Jowett A, Stables J, Topley P, Wood ER, Brignola PS, Kadwell SH, Reep BR, Mullin RJ, Alligood KJ, Keith BR, Crosby RM, Murray DM, Knight WB, Gilmer TM, Lackey K. Cancer Res; 2001 Oct 01; 61(19):7196-203. PubMed ID: 11585755 [Abstract] [Full Text] [Related]
3. Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo. Moulder SL, Yakes FM, Muthuswamy SK, Bianco R, Simpson JF, Arteaga CL. Cancer Res; 2001 Dec 15; 61(24):8887-95. PubMed ID: 11751413 [Abstract] [Full Text] [Related]
5. Discovery and biological evaluation of potent dual ErbB-2/EGFR tyrosine kinase inhibitors: 6-thiazolylquinazolines. Gaul MD, Guo Y, Affleck K, Cockerill GS, Gilmer TM, Griffin RJ, Guntrip S, Keith BR, Knight WB, Mullin RJ, Murray DM, Rusnak DW, Smith K, Tadepalli S, Wood ER, Lackey K. Bioorg Med Chem Lett; 2003 Feb 24; 13(4):637-40. PubMed ID: 12639547 [Abstract] [Full Text] [Related]
6. AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity. Traxler P, Allegrini PR, Brandt R, Brueggen J, Cozens R, Fabbro D, Grosios K, Lane HA, McSheehy P, Mestan J, Meyer T, Tang C, Wartmann M, Wood J, Caravatti G. Cancer Res; 2004 Jul 15; 64(14):4931-41. PubMed ID: 15256466 [Abstract] [Full Text] [Related]
7. Novel targeted approaches to treating biliary tract cancer: the dual epidermal growth factor receptor and ErbB-2 tyrosine kinase inhibitor NVP-AEE788 is more efficient than the epidermal growth factor receptor inhibitors gefitinib and erlotinib. Wiedmann M, Feisthammel J, Blüthner T, Tannapfel A, Kamenz T, Kluge A, Mössner J, Caca K. Anticancer Drugs; 2006 Aug 15; 17(7):783-95. PubMed ID: 16926628 [Abstract] [Full Text] [Related]
8. AST1306, a novel irreversible inhibitor of the epidermal growth factor receptor 1 and 2, exhibits antitumor activity both in vitro and in vivo. Xie H, Lin L, Tong L, Jiang Y, Zheng M, Chen Z, Jiang X, Zhang X, Ren X, Qu W, Yang Y, Wan H, Chen Y, Zuo J, Jiang H, Geng M, Ding J. PLoS One; 2011 Aug 15; 6(7):e21487. PubMed ID: 21789172 [Abstract] [Full Text] [Related]
9. The biological and biochemical effects of CP-654577, a selective erbB2 kinase inhibitor, on human breast cancer cells. Barbacci EG, Pustilnik LR, Rossi AM, Emerson E, Miller PE, Boscoe BP, Cox ED, Iwata KK, Jani JP, Provoncha K, Kath JC, Liu Z, Moyer JD. Cancer Res; 2003 Aug 01; 63(15):4450-9. PubMed ID: 12907618 [Abstract] [Full Text] [Related]
10. ZD1839 (Iressa), a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, potently inhibits the growth of EGFR-positive cancer cell lines with or without erbB2 overexpression. Anderson NG, Ahmad T, Chan K, Dobson R, Bundred NJ. Int J Cancer; 2001 Dec 15; 94(6):774-82. PubMed ID: 11745477 [Abstract] [Full Text] [Related]
11. SKLB1206, a novel orally available multikinase inhibitor targeting EGFR activating and T790M mutants, ErbB2, ErbB4, and VEGFR2, displays potent antitumor activity both in vitro and in vivo. Pan Y, Xu Y, Feng S, Luo S, Zheng R, Yang J, Wang L, Zhong L, Yang HY, Wang BL, Yu Y, Liu J, Cao Z, Wang X, Ji P, Wang Z, Chen X, Zhang S, Wei YQ, Yang SY. Mol Cancer Ther; 2012 Apr 15; 11(4):952-62. PubMed ID: 22319204 [Abstract] [Full Text] [Related]
12. Antitumor and antiangiogenic effect of the dual EGFR and HER-2 tyrosine kinase inhibitor lapatinib in a lung cancer model. Diaz R, Nguewa PA, Parrondo R, Perez-Stable C, Manrique I, Redrado M, Catena R, Collantes M, Peñuelas I, Díaz-González JA, Calvo A. BMC Cancer; 2010 May 11; 10():188. PubMed ID: 20459769 [Abstract] [Full Text] [Related]
13. Indazolylamino quinazolines and pyridopyrimidines as inhibitors of the EGFr and C-erbB-2. Cockerill S, Stubberfield C, Stables J, Carter M, Guntrip S, Smith K, McKeown S, Shaw R, Topley P, Thomsen L, Affleck K, Jowett A, Hayes D, Willson M, Woollard P, Spalding D. Bioorg Med Chem Lett; 2001 Jun 04; 11(11):1401-5. PubMed ID: 11378364 [Abstract] [Full Text] [Related]
15. Effects of the EGFR/HER2 kinase inhibitor GW572016 on EGFR- and HER2-overexpressing breast cancer cell line proliferation, radiosensitization, and resistance. Zhou H, Kim YS, Peletier A, McCall W, Earp HS, Sartor CI. Int J Radiat Oncol Biol Phys; 2004 Feb 01; 58(2):344-52. PubMed ID: 14751502 [Abstract] [Full Text] [Related]
16. ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells. Anido J, Matar P, Albanell J, Guzmán M, Rojo F, Arribas J, Averbuch S, Baselga J. Clin Cancer Res; 2003 Apr 01; 9(4):1274-83. PubMed ID: 12684395 [Abstract] [Full Text] [Related]
17. The efficacy of ErbB receptor-targeted anticancer therapeutics is influenced by the availability of epidermal growth factor-related peptides. Motoyama AB, Hynes NE, Lane HA. Cancer Res; 2002 Jun 01; 62(11):3151-8. PubMed ID: 12036928 [Abstract] [Full Text] [Related]