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317 related items for PubMed ID: 12469113

  • 21. NMR backbone assignment of a protein kinase catalytic domain by a combination of several approaches: application to the catalytic subunit of cAMP-dependent protein kinase.
    Langer T, Vogtherr M, Elshorst B, Betz M, Schieborr U, Saxena K, Schwalbe H.
    Chembiochem; 2004 Nov 05; 5(11):1508-16. PubMed ID: 15481030
    [Abstract] [Full Text] [Related]

  • 22. Structure of the unliganded cAMP-dependent protein kinase catalytic subunit from Saccharomyces cerevisiae.
    Mashhoon N, Carmel G, Pflugrath JW, Kuret J.
    Arch Biochem Biophys; 2001 Mar 01; 387(1):11-9. PubMed ID: 11368172
    [Abstract] [Full Text] [Related]

  • 23. Conformational differences among solution structures of the type Ialpha, IIalpha and IIbeta protein kinase A regulatory subunit homodimers: role of the linker regions.
    Vigil D, Blumenthal DK, Heller WT, Brown S, Canaves JM, Taylor SS, Trewhella J.
    J Mol Biol; 2004 Apr 09; 337(5):1183-94. PubMed ID: 15046986
    [Abstract] [Full Text] [Related]

  • 24. Definition of an electrostatic relay switch critical for the cAMP-dependent activation of protein kinase A as revealed by the D170A mutant of RIalpha.
    Abu-Abed M, Das R, Wang L, Melacini G.
    Proteins; 2007 Oct 01; 69(1):112-24. PubMed ID: 17596845
    [Abstract] [Full Text] [Related]

  • 25. Entropy-driven cAMP-dependent allosteric control of inhibitory interactions in exchange proteins directly activated by cAMP.
    Das R, Mazhab-Jafari MT, Chowdhury S, SilDas S, Selvaratnam R, Melacini G.
    J Biol Chem; 2008 Jul 11; 283(28):19691-703. PubMed ID: 18411261
    [Abstract] [Full Text] [Related]

  • 26. Numerous distinct PKA-, or EPAC-based, signalling complexes allow selective phosphodiesterase 3 and phosphodiesterase 4 coordination of cell adhesion.
    Raymond DR, Wilson LS, Carter RL, Maurice DH.
    Cell Signal; 2007 Dec 11; 19(12):2507-18. PubMed ID: 17884339
    [Abstract] [Full Text] [Related]

  • 27. Cyclic AMP-dependent, protein kinase A-independent activation of extracellular signal-regulated kinase 1/2 following adenosine receptor stimulation in human umbilical vein endothelial cells: role of exchange protein activated by cAMP 1 (Epac1).
    Fang Y, Olah ME.
    J Pharmacol Exp Ther; 2007 Sep 11; 322(3):1189-200. PubMed ID: 17565009
    [Abstract] [Full Text] [Related]

  • 28. Regulation of aldosterone production from zona glomerulosa cells by ANG II and cAMP: evidence for PKA-independent activation of CaMK by cAMP.
    Gambaryan S, Butt E, Tas P, Smolenski A, Allolio B, Walter U.
    Am J Physiol Endocrinol Metab; 2006 Mar 11; 290(3):E423-33. PubMed ID: 16219670
    [Abstract] [Full Text] [Related]

  • 29. Probing cAMP-dependent protein kinase holoenzyme complexes I alpha and II beta by FT-IR and chemical protein footprinting.
    Yu S, Mei FC, Lee JC, Cheng X.
    Biochemistry; 2004 Feb 24; 43(7):1908-20. PubMed ID: 14967031
    [Abstract] [Full Text] [Related]

  • 30. Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel.
    Clayton GM, Silverman WR, Heginbotham L, Morais-Cabral JH.
    Cell; 2004 Nov 24; 119(5):615-27. PubMed ID: 15550244
    [Abstract] [Full Text] [Related]

  • 31. Dynamic binding of PKA regulatory subunit RI alpha.
    Gullingsrud J, Kim C, Taylor SS, McCammon JA.
    Structure; 2006 Jan 24; 14(1):141-9. PubMed ID: 16407073
    [Abstract] [Full Text] [Related]

  • 32. Ndel1 alters its conformation by sequestering cAMP-specific phosphodiesterase-4D3 (PDE4D3) in a manner that is dynamically regulated through Protein Kinase A (PKA).
    Collins DM, Murdoch H, Dunlop AJ, Charych E, Baillie GS, Wang Q, Herberg FW, Brandon N, Prinz A, Houslay MD.
    Cell Signal; 2008 Dec 24; 20(12):2356-69. PubMed ID: 18845247
    [Abstract] [Full Text] [Related]

  • 33. Mapping ligand interactions with the hyperpolarization activated cyclic nucleotide modulated (HCN) ion channel binding domain using a soluble construct.
    Scott SP, Shea PW, Dryer SE.
    Biochemistry; 2007 Aug 21; 46(33):9417-31. PubMed ID: 17655202
    [Abstract] [Full Text] [Related]

  • 34. Catalytic independent functions of a protein kinase as revealed by a kinase-dead mutant: study of the Lys72His mutant of cAMP-dependent kinase.
    Iyer GH, Garrod S, Woods VL, Taylor SS.
    J Mol Biol; 2005 Sep 02; 351(5):1110-22. PubMed ID: 16054648
    [Abstract] [Full Text] [Related]

  • 35. Rearrangements in a hydrophobic core region mediate cAMP action in the regulatory subunit of PKA.
    Hahnefeld C, Moll D, Goette M, Herberg FW.
    Biol Chem; 2005 Jul 02; 386(7):623-31. PubMed ID: 16207083
    [Abstract] [Full Text] [Related]

  • 36. A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.
    Enserink JM, Christensen AE, de Rooij J, van Triest M, Schwede F, Genieser HG, Døskeland SO, Blank JL, Bos JL.
    Nat Cell Biol; 2002 Nov 02; 4(11):901-6. PubMed ID: 12402047
    [Abstract] [Full Text] [Related]

  • 37. Regulating Rap small G-proteins in time and space.
    Gloerich M, Bos JL.
    Trends Cell Biol; 2011 Oct 02; 21(10):615-23. PubMed ID: 21820312
    [Abstract] [Full Text] [Related]

  • 38. Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP.
    de Rooij J, Zwartkruis FJ, Verheijen MH, Cool RH, Nijman SM, Wittinghofer A, Bos JL.
    Nature; 1998 Dec 03; 396(6710):474-7. PubMed ID: 9853756
    [Abstract] [Full Text] [Related]

  • 39. The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1).
    Courilleau D, Bouyssou P, Fischmeister R, Lezoualc'h F, Blondeau JP.
    Biochem Biophys Res Commun; 2013 Oct 25; 440(3):443-8. PubMed ID: 24099776
    [Abstract] [Full Text] [Related]

  • 40. A new phospholipase-C-calcium signalling pathway mediated by cyclic AMP and a Rap GTPase.
    Schmidt M, Evellin S, Weernink PA, von Dorp F, Rehmann H, Lomasney JW, Jakobs KH.
    Nat Cell Biol; 2001 Nov 25; 3(11):1020-4. PubMed ID: 11715024
    [Abstract] [Full Text] [Related]

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