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163 related items for PubMed ID: 12473561

  • 1. NCX-4016 (NO-aspirin) inhibits lipopolysaccharide-induced tissue factor expression in vivo: role of nitric oxide.
    Fiorucci S, Mencarelli A, Meneguzzi A, Lechi A, Morelli A, del Soldato P, Minuz P.
    Circulation; 2002 Dec 10; 106(24):3120-5. PubMed ID: 12473561
    [Abstract] [Full Text] [Related]

  • 2. Co-administration of nitric oxide-aspirin (NCX-4016) and aspirin prevents platelet and monocyte activation and protects against gastric damage induced by aspirin in humans.
    Fiorucci S, Mencarelli A, Meneguzzi A, Lechi A, Renga B, del Soldato P, Morelli A, Minuz P.
    J Am Coll Cardiol; 2004 Aug 04; 44(3):635-41. PubMed ID: 15358033
    [Abstract] [Full Text] [Related]

  • 3. Aspirin, but not NO-releasing aspirin (NCX-4016), interacts with selective COX-2 inhibitors to aggravate gastric damage and inflammation.
    Wallace JL, Zamuner SR, McKnight W, Dicay M, Mencarelli A, del Soldato P, Fiorucci S.
    Am J Physiol Gastrointest Liver Physiol; 2004 Jan 04; 286(1):G76-81. PubMed ID: 14665439
    [Abstract] [Full Text] [Related]

  • 4. Cyclooxygenase-2 selective and nitric oxide-releasing nonsteroidal anti-inflammatory drugs and gastric mucosal responses.
    Takeuchi K, Suzuki K, Yamamoto H, Araki H, Mizoguchi H, Ukawa H.
    J Physiol Pharmacol; 1998 Dec 04; 49(4):501-13. PubMed ID: 10069692
    [Abstract] [Full Text] [Related]

  • 5. Classic NSAID and selective cyclooxygenase (COX)-1 and COX-2 inhibitors in healing of chronic gastric ulcers.
    Brzozowski T, Konturek PC, Konturek SJ, Sliwowski Z, Pajdo R, Drozdowicz D, Ptak A, Hahn EG.
    Microsc Res Tech; 2001 Jun 01; 53(5):343-53. PubMed ID: 11376495
    [Abstract] [Full Text] [Related]

  • 6. Effects of aspirin and NO-aspirin (NCX 4016) on platelet function and coagulation in human endotoxemia.
    Derhaschnig U, Schweeger-Exeli I, Marsik C, Cardona F, Minuz P, Jilma B.
    Platelets; 2010 Jun 01; 21(5):320-8. PubMed ID: 20608787
    [Abstract] [Full Text] [Related]

  • 7. Effects of cyclooxygenase-2 selective and nitric oxide-releasing nonsteroidal antiinflammatory drugs on mucosal ulcerogenic and healing responses of the stomach.
    Ukawa H, Yamakuni H, Kato S, Takeuchi K.
    Dig Dis Sci; 1998 Sep 01; 43(9):2003-11. PubMed ID: 9753266
    [Abstract] [Full Text] [Related]

  • 8. IL-1 beta converting enzyme is a target for nitric oxide-releasing aspirin: new insights in the antiinflammatory mechanism of nitric oxide-releasing nonsteroidal antiinflammatory drugs.
    Fiorucci S, Santucci L, Cirino G, Mencarelli A, Familiari L, Soldato PD, Morelli A.
    J Immunol; 2000 Nov 01; 165(9):5245-54. PubMed ID: 11046058
    [Abstract] [Full Text] [Related]

  • 9. Gastroprotective and ulcer healing effects of nitric oxide-releasing non-steroidal anti-inflammatory drugs.
    Brzozowski T, Konturek PC, Konturek SJ, Sliwowski Z, Drozdowicz D, Kwiecień S, Pajdo R, Ptak A, Pawlik M, Hahn E.
    Dig Liver Dis; 2000 Oct 01; 32(7):583-94. PubMed ID: 11142556
    [Abstract] [Full Text] [Related]

  • 10. NCX4016 (NO-aspirin) inhibits thromboxane biosynthesis and tissue factor expression and activity in human monocytes.
    Minuz P, Degan M, Gaino S, Meneguzzi A, Zuliani V, Lechi Santonastaso C, Del Soldato P, Lechi A.
    Med Sci Monit; 2001 Oct 01; 7(4):573-7. PubMed ID: 11433179
    [Abstract] [Full Text] [Related]

  • 11. Nitric oxide-releasing NSAIDs inhibit interleukin-1beta converting enzyme-like cysteine proteases and protect endothelial cells from apoptosis induced by TNFalpha.
    Fiorucci S, Santucci L, Federici B, Antonelli E, Distrutti E, Morelli O, Renzo GD, Coata G, Cirino G, Soldato PD, Morelli A.
    Aliment Pharmacol Ther; 1999 Mar 01; 13(3):421-35. PubMed ID: 10102977
    [Abstract] [Full Text] [Related]

  • 12. Nitric oxide (NO)-releasing naproxen (HCT-3012 [(S)-6-methoxy-alpha-methyl-2-naphthaleneacetic Acid 4-(nitrooxy)butyl ester]) interactions with aspirin in gastric mucosa of arthritic rats reveal a role for aspirin-triggered lipoxin, prostaglandins, and NO in gastric protection.
    Fiorucci S, Di Lorenzo A, Renga B, Farneti S, Morelli A, Cirino G.
    J Pharmacol Exp Ther; 2004 Dec 01; 311(3):1264-71. PubMed ID: 15297470
    [Abstract] [Full Text] [Related]

  • 13. Activation of genes for spasmolytic peptide, transforming growth factor alpha and for cyclooxygenase (COX)-1 and COX-2 during gastric adaptation to aspirin damage in rats.
    Konturek PC, Brzozowski T, Pierzchalski P, Kwiecien S, Pajdo R, Hahn EG, Konturek SJ.
    Aliment Pharmacol Ther; 1998 Aug 01; 12(8):767-77. PubMed ID: 9726391
    [Abstract] [Full Text] [Related]

  • 14. NCX4016 (NO-Aspirin) has multiple inhibitory effects in LPS-stimulated human monocytes.
    Minuz P, Degan M, Gaino S, Meneguzzi A, Zuliani V, Santonastaso CL, Soldato PD, Lechi A.
    Br J Pharmacol; 2001 Oct 01; 134(4):905-11. PubMed ID: 11606332
    [Abstract] [Full Text] [Related]

  • 15. Gastrointestinal safety of nitric oxide-derived aspirin is related to inhibition of ICE-like cysteine proteases in rats.
    Fiorucci S, Antonelli E, Santucci L, Morelli O, Miglietti M, Federici B, Mannucci R, Del Soldato P, Morelli A.
    Gastroenterology; 1999 May 01; 116(5):1089-106. PubMed ID: 10220501
    [Abstract] [Full Text] [Related]

  • 16. Nitric oxide (NO)-releasing aspirin exhibits a potent esophagoprotection in experimental model of acute reflux esophagitis. Role of nitric oxide and proinflammatory cytokines.
    Pawlik M, Pajdo R, Kwiecien S, Ptak-Belowska A, Sliwowski Z, Mazurkiewicz-Janik M, Konturek SJ, Pawlik WW, Brzozowski T.
    J Physiol Pharmacol; 2011 Feb 01; 62(1):75-86. PubMed ID: 21451212
    [Abstract] [Full Text] [Related]

  • 17. Characterization of the induction of nitric oxide synthase and cyclo-oxygenase in rat aorta in organ culture.
    Bishop-Bailey D, Larkin SW, Warner TD, Chen G, Mitchell JA.
    Br J Pharmacol; 1997 May 01; 121(1):125-33. PubMed ID: 9146896
    [Abstract] [Full Text] [Related]

  • 18. Nitric oxide-releasing aspirin protects gastric mucosa against ethanol damage in rats with functional ablation of sensory nerves.
    Konturek PC, Brzozowski T, Kania J, Konturek SJ, Hahn EG.
    Inflamm Res; 2003 Sep 01; 52(9):359-65. PubMed ID: 14504662
    [Abstract] [Full Text] [Related]

  • 19. Anti-thrombotic effects of a nitric oxide-releasing, gastric-sparing aspirin derivative.
    Wallace JL, McKnight W, Del Soldato P, Baydoun AR, Cirino G.
    J Clin Invest; 1995 Dec 01; 96(6):2711-8. PubMed ID: 8675638
    [Abstract] [Full Text] [Related]

  • 20. Healing of chronic gastric ulcers in diabetic rats treated with native aspirin, nitric oxide (NO)-derivative of aspirin and cyclooxygenase (COX)-2 inhibitor.
    Brzozowska I, Targosz A, Sliwowski Z, Kwiecien S, Drozdowicz D, Pajdo R, Konturek PC, Brzozowski T, Pawlik M, Konturek SJ, Pawlik WW, Hahn EG.
    J Physiol Pharmacol; 2004 Dec 01; 55(4):773-90. PubMed ID: 15613743
    [Abstract] [Full Text] [Related]


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