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286 related items for PubMed ID: 12475986

  • 1. Troglitazone, a peroxisome proliferator-activated receptor gamma (PPAR gamma ) ligand, selectively induces the early growth response-1 gene independently of PPAR gamma. A novel mechanism for its anti-tumorigenic activity.
    Baek SJ, Wilson LC, Hsi LC, Eling TE.
    J Biol Chem; 2003 Feb 21; 278(8):5845-53. PubMed ID: 12475986
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  • 2. Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1.
    Baek SJ, Kim JS, Nixon JB, DiAugustine RP, Eling TE.
    J Biol Chem; 2004 Feb 20; 279(8):6883-92. PubMed ID: 14662774
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  • 8. Ligand activation of peroxisome proliferator-activated receptor gamma induces apoptosis of leukemia cells by down-regulating the c-myc gene expression via blockade of the Tcf-4 activity.
    Yamakawa-Karakida N, Sugita K, Inukai T, Goi K, Nakamura M, Uno K, Sato H, Kagami K, Barker N, Nakazawa S.
    Cell Death Differ; 2002 May 20; 9(5):513-26. PubMed ID: 11973610
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  • 9. Regulation of the growth arrest and DNA damage-inducible gene 45 (GADD45) by peroxisome proliferator-activated receptor gamma in vascular smooth muscle cells.
    Bruemmer D, Yin F, Liu J, Berger JP, Sakai T, Blaschke F, Fleck E, Van Herle AJ, Forman BM, Law RE.
    Circ Res; 2003 Aug 22; 93(4):e38-47. PubMed ID: 12881480
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  • 10. Growth inhibition of esophageal squamous carcinoma cells by peroxisome proliferator-activated receptor-gamma ligands.
    Rumi MA, Sato H, Ishihara S, Ortega C, Kadowaki Y, Kinoshita Y.
    J Lab Clin Med; 2002 Jul 22; 140(1):17-26. PubMed ID: 12080324
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  • 11. Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1.
    Cheng S, Afif H, Martel-Pelletier J, Pelletier JP, Li X, Farrajota K, Lavigne M, Fahmi H.
    J Biol Chem; 2004 May 21; 279(21):22057-65. PubMed ID: 15023995
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  • 12. A novel peroxisome proliferator-activated receptor gamma ligand, MCC-555, induces apoptosis via posttranscriptional regulation of NAG-1 in colorectal cancer cells.
    Yamaguchi K, Lee SH, Eling TE, Baek SJ.
    Mol Cancer Ther; 2006 May 21; 5(5):1352-61. PubMed ID: 16731769
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  • 13. Troglitazone, an antidiabetic agent, inhibits cholesterol biosynthesis through a mechanism independent of peroxisome proliferator-activated receptor-gamma.
    Wang M, Wise SC, Leff T, Su TZ.
    Diabetes; 1999 Feb 21; 48(2):254-60. PubMed ID: 10334298
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  • 16. Activation of peroxisome proliferator-activated receptor gamma by troglitazone inhibits cell growth through the increase of p27KiP1 in human. Pancreatic carcinoma cells.
    Motomura W, Okumura T, Takahashi N, Obara T, Kohgo Y.
    Cancer Res; 2000 Oct 01; 60(19):5558-64. PubMed ID: 11034103
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  • 17. PPAR-gamma ligands inhibit growth of human esophageal adenocarcinoma cells through induction of apoptosis, cell cycle arrest and reduction of ornithine decarboxylase activity.
    Takashima T, Fujiwara Y, Higuchi K, Arakawa T, Yano Y, Hasuma T, Otani S.
    Int J Oncol; 2001 Sep 01; 19(3):465-71. PubMed ID: 11494023
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  • 18. Differential activation of peroxisome proliferator-activated receptor-gamma by troglitazone and rosiglitazone.
    Camp HS, Li O, Wise SC, Hong YH, Frankowski CL, Shen X, Vanbogelen R, Leff T.
    Diabetes; 2000 Apr 01; 49(4):539-47. PubMed ID: 10871190
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  • 19. Unique ability of troglitazone to up-regulate peroxisome proliferator-activated receptor-gamma expression in hepatocytes.
    Davies GF, McFie PJ, Khandelwal RL, Roesler WJ.
    J Pharmacol Exp Ther; 2002 Jan 01; 300(1):72-7. PubMed ID: 11752099
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  • 20. Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells.
    Shimada T, Kojima K, Yoshiura K, Hiraishi H, Terano A.
    Gut; 2002 May 01; 50(5):658-64. PubMed ID: 11950812
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