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Journal Abstract Search

210 related items for PubMed ID: 12480937

  • 1. Secretion and intracellular generation of truncated Abeta in beta-site amyloid-beta precursor protein-cleaving enzyme expressing human neurons.
    Lee EB, Skovronsky DM, Abtahian F, Doms RW, Lee VM.
    J Biol Chem; 2003 Feb 14; 278(7):4458-66. PubMed ID: 12480937
    [Abstract] [Full Text] [Related]

  • 2. Characterization of Abeta11-40/42 peptide deposition in Alzheimer's disease and young Down's syndrome brains: implication of N-terminally truncated Abeta species in the pathogenesis of Alzheimer's disease.
    Liu K, Solano I, Mann D, Lemere C, Mercken M, Trojanowski JQ, Lee VM.
    Acta Neuropathol; 2006 Aug 14; 112(2):163-74. PubMed ID: 16865398
    [Abstract] [Full Text] [Related]

  • 3. Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients.
    Li R, Lindholm K, Yang LB, Yue X, Citron M, Yan R, Beach T, Sue L, Sabbagh M, Cai H, Wong P, Price D, Shen Y.
    Proc Natl Acad Sci U S A; 2004 Mar 09; 101(10):3632-7. PubMed ID: 14978286
    [Abstract] [Full Text] [Related]

  • 4. Effects of TNFalpha-converting enzyme inhibition on amyloid beta production and APP processing in vitro and in vivo.
    Kim ML, Zhang B, Mills IP, Milla ME, Brunden KR, Lee VM.
    J Neurosci; 2008 Nov 12; 28(46):12052-61. PubMed ID: 19005070
    [Abstract] [Full Text] [Related]

  • 5. BACE overexpression alters the subcellular processing of APP and inhibits Abeta deposition in vivo.
    Lee EB, Zhang B, Liu K, Greenbaum EA, Doms RW, Trojanowski JQ, Lee VM.
    J Cell Biol; 2005 Jan 17; 168(2):291-302. PubMed ID: 15642747
    [Abstract] [Full Text] [Related]

  • 6. Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells.
    Wiltfang J, Esselmann H, Cupers P, Neumann M, Kretzschmar H, Beyermann M, Schleuder D, Jahn H, Rüther E, Kornhuber J, Annaert W, De Strooper B, Saftig P.
    J Biol Chem; 2001 Nov 16; 276(46):42645-57. PubMed ID: 11526104
    [Abstract] [Full Text] [Related]

  • 7. Reduced Aβ secretion by human neurons under conditions of strongly increased BACE activity.
    Scholz D, Chernyshova Y, Ückert AK, Leist M.
    J Neurochem; 2018 Oct 16; 147(2):256-274. PubMed ID: 29804308
    [Abstract] [Full Text] [Related]

  • 8. Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice.
    Yamamoto M, Kiyota T, Horiba M, Buescher JL, Walsh SM, Gendelman HE, Ikezu T.
    Am J Pathol; 2007 Feb 16; 170(2):680-92. PubMed ID: 17255335
    [Abstract] [Full Text] [Related]

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  • 10. beta-site amyloid precursor protein cleaving enzyme 1 increases amyloid deposition in brain parenchyma but reduces cerebrovascular amyloid angiopathy in aging BACE x APP[V717I] double-transgenic mice.
    Willem M, Dewachter I, Smyth N, Van Dooren T, Borghgraef P, Haass C, Van Leuven F.
    Am J Pathol; 2004 Nov 16; 165(5):1621-31. PubMed ID: 15509532
    [Abstract] [Full Text] [Related]

  • 11. Glu11 site cleavage and N-terminally truncated A beta production upon BACE overexpression.
    Liu K, Doms RW, Lee VM.
    Biochemistry; 2002 Mar 05; 41(9):3128-36. PubMed ID: 11863452
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  • 13. The Arctic amyloid-β precursor protein (AβPP) mutation results in distinct plaques and accumulation of N- and C-truncated Aβ.
    Philipson O, Lord A, Lalowski M, Soliymani R, Baumann M, Thyberg J, Bogdanovic N, Olofsson T, Tjernberg LO, Ingelsson M, Lannfelt L, Kalimo H, Nilsson LN.
    Neurobiol Aging; 2012 May 05; 33(5):1010.e1-13. PubMed ID: 22118948
    [Abstract] [Full Text] [Related]

  • 14. Alzheimer's disease.
    De-Paula VJ, Radanovic M, Diniz BS, Forlenza OV.
    Subcell Biochem; 2012 May 05; 65():329-52. PubMed ID: 23225010
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  • 16. Generation of aggregation prone N-terminally truncated amyloid β peptides by meprin β depends on the sequence specificity at the cleavage site.
    Schönherr C, Bien J, Isbert S, Wichert R, Prox J, Altmeppen H, Kumar S, Walter J, Lichtenthaler SF, Weggen S, Glatzel M, Becker-Pauly C, Pietrzik CU.
    Mol Neurodegener; 2016 Feb 19; 11():19. PubMed ID: 26895626
    [Abstract] [Full Text] [Related]

  • 17. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
    Kimura A, Hata S, Suzuki T.
    J Biol Chem; 2016 Nov 11; 291(46):24041-24053. PubMed ID: 27687728
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  • 19. Transgenic BACE expression in mouse neurons accelerates amyloid plaque pathology.
    Mohajeri MH, Saini KD, Nitsch RM.
    J Neural Transm (Vienna); 2004 Mar 11; 111(3):413-25. PubMed ID: 14991462
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