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211 related items for PubMed ID: 12486497

  • 1. Decrease in the insulin receptor protein level by anti-insulin receptor antibodies: roles of tyrosine kinase activity and receptor internalization.
    Fujita N, Yamasaki H, Yamakawa K, Uotani S, Kuwahara H, Degawa-Yamauchi M, Abe T, Ozaki M, Sera Y, Kawasaki E, Takino H, Yamaguchi Y, Eguchi K.
    Acta Diabetol; 2002 Dec; 39(4):221-7. PubMed ID: 12486497
    [Abstract] [Full Text] [Related]

  • 2. Antiinsulin receptor autoantibodies induce insulin receptors to constitutively associate with insulin receptor substrate-1 and -2 and cause severe cell resistance to both insulin and insulin-like growth factor I.
    Auclair M, Vigouroux C, Desbois-Mouthon C, Deibener J, Kaminski P, Lascols O, Cherqui G, Capeau J, Caron M.
    J Clin Endocrinol Metab; 1999 Sep; 84(9):3197-206. PubMed ID: 10487687
    [Abstract] [Full Text] [Related]

  • 3. Augmented growth response to IGF-1 via increased IRS-1 in Chinese hamster ovary cells expressing kinase-negative insulin receptors.
    Inoue S, Fukuda K, Kudara T, Igura T, Inui Y, Tamura S, Hanafusa T, Kawata S, Matsuzawa Y.
    Diabetologia; 1999 Jun; 42(6):763-72. PubMed ID: 10382598
    [Abstract] [Full Text] [Related]

  • 4. Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.
    Batty IH, Fleming IN, Downes CP.
    Biochem J; 2004 May 01; 379(Pt 3):641-51. PubMed ID: 14769130
    [Abstract] [Full Text] [Related]

  • 5. An arginine to cysteine(252) mutation in insulin receptors from a patient with severe insulin resistance inhibits receptor internalisation but preserves signalling events.
    Hamer I, Foti M, Emkey R, Cordier-Bussat M, Philippe J, De Meyts P, Maeder C, Kahn CR, Carpentier JL.
    Diabetologia; 2002 May 01; 45(5):657-67. PubMed ID: 12107746
    [Abstract] [Full Text] [Related]

  • 6. Dual regulation of upstream binding factor 1 levels by IRS-1 and ERKs in IGF-1-receptor signaling.
    Sun H, Tu X, Liu M, Baserga R.
    J Cell Physiol; 2007 Sep 01; 212(3):780-6. PubMed ID: 17443674
    [Abstract] [Full Text] [Related]

  • 7. Insulin/IGF-1 hybrid receptors: implications for the dominant-negative phenotype in syndromes of insulin resistance.
    Frattali AL, Treadway JL, Pessin JE.
    J Cell Biochem; 1992 Jan 01; 48(1):43-50. PubMed ID: 1316361
    [Abstract] [Full Text] [Related]

  • 8. Cholera toxin diminishes tyrosine kinase activity of the insulin receptor.
    Müller-Wieland D, Krone W.
    Biochem Int; 1992 Oct 01; 28(1):161-8. PubMed ID: 1445389
    [Abstract] [Full Text] [Related]

  • 9. Nitric oxide mediates the survival action of IGF-1 and insulin in pancreatic beta cells.
    Cahuana GM, Tejedo JR, Hmadcha A, Ramírez R, Cuesta AL, Soria B, Martin F, Bedoya FJ.
    Cell Signal; 2008 Feb 01; 20(2):301-10. PubMed ID: 18023142
    [Abstract] [Full Text] [Related]

  • 10. Adapter protein with a pleckstrin homology (PH) and an Src homology 2 (SH2) domain (APS) and SH2-B enhance insulin-receptor autophosphorylation, extracellular-signal-regulated kinase and phosphoinositide 3-kinase-dependent signalling.
    Ahmed Z, Pillay TS.
    Biochem J; 2003 Apr 15; 371(Pt 2):405-12. PubMed ID: 12521378
    [Abstract] [Full Text] [Related]

  • 11. Insulin receptor substrate-4 signaling in quiescent rat hepatocytes and in regenerating rat liver.
    Escribano O, Fernández-Moreno MD, Zueco JA, Menor C, Fueyo J, Ropero RM, Diaz-Laviada I, Román ID, Guijarro LG.
    Hepatology; 2003 Jun 15; 37(6):1461-9. PubMed ID: 12774026
    [Abstract] [Full Text] [Related]

  • 12. A mechanism for cell size regulation by the insulin and insulin-like growth factor-I receptors.
    Sun H, Tu X, Baserga R.
    Cancer Res; 2006 Dec 01; 66(23):11106-9. PubMed ID: 17145851
    [Abstract] [Full Text] [Related]

  • 13. Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors.
    Denley A, Carroll JM, Brierley GV, Cosgrove L, Wallace J, Forbes B, Roberts CT.
    Mol Cell Biol; 2007 May 01; 27(10):3569-77. PubMed ID: 17325037
    [Abstract] [Full Text] [Related]

  • 14. Epidermal growth factor induces insulin receptor substrate-2 in breast cancer cells via c-Jun NH(2)-terminal kinase/activator protein-1 signaling to regulate cell migration.
    Cui X, Kim HJ, Kuiatse I, Kim H, Brown PH, Lee AV.
    Cancer Res; 2006 May 15; 66(10):5304-13. PubMed ID: 16707456
    [Abstract] [Full Text] [Related]

  • 15. IRS-1 is a common element in insulin and insulin-like growth factor-I signaling to the phosphatidylinositol 3'-kinase.
    Myers MG, Sun XJ, Cheatham B, Jachna BR, Glasheen EM, Backer JM, White MF.
    Endocrinology; 1993 Apr 15; 132(4):1421-30. PubMed ID: 8384986
    [Abstract] [Full Text] [Related]

  • 16. A chimeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I.
    Sachdev D, Li SL, Hartell JS, Fujita-Yamaguchi Y, Miller JS, Yee D.
    Cancer Res; 2003 Feb 01; 63(3):627-35. PubMed ID: 12566306
    [Abstract] [Full Text] [Related]

  • 17. In vitro phosphorylation of insulin receptor substrate 1 by protein kinase C-zeta: functional analysis and identification of novel phosphorylation sites.
    Sommerfeld MR, Metzger S, Stosik M, Tennagels N, Eckel J.
    Biochemistry; 2004 May 18; 43(19):5888-901. PubMed ID: 15134463
    [Abstract] [Full Text] [Related]

  • 18. Insulin receptor signaling through non-tyrosine kinase pathways: evidence from anti-receptor antibodies and insulin receptor mutants.
    Sung CK.
    J Cell Biochem; 1992 Jan 18; 48(1):26-32. PubMed ID: 1316358
    [Abstract] [Full Text] [Related]

  • 19. Progesterone crosstalks with insulin-like growth factor signaling in breast cancer cells via induction of insulin receptor substrate-2.
    Cui X, Lazard Z, Zhang P, Hopp TA, Lee AV.
    Oncogene; 2003 Oct 09; 22(44):6937-41. PubMed ID: 14534541
    [Abstract] [Full Text] [Related]

  • 20. Insulin receptor autophosphorylation and exogenous substrate phosphorylation: role of receptor C-terminus and effects of mild reduction.
    Clark S, Konstantopoulos N.
    Biochem Biophys Res Commun; 1994 Apr 15; 200(1):330-7. PubMed ID: 8166701
    [Abstract] [Full Text] [Related]

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