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135 related items for PubMed ID: 12488357

  • 1. Trafficking of mutant carboxypeptidase E to secretory granules in a beta-cell line derived from Cpe(fat)/Cpe(fat) mice.
    Cawley NX, Rodriguez YM, Maldonado A, Loh YP.
    Endocrinology; 2003 Jan; 144(1):292-8. PubMed ID: 12488357
    [Abstract] [Full Text] [Related]

  • 2. Beta-cell lines derived from transgenic Cpe(fat)/Cpe(fat) mice are defective in carboxypeptidase E and proinsulin processing.
    Varlamov O, Fricker LD, Furukawa H, Steiner DF, Langley SH, Leiter EH.
    Endocrinology; 1997 Nov; 138(11):4883-92. PubMed ID: 9348219
    [Abstract] [Full Text] [Related]

  • 3. The sorting of proglucagon to secretory granules is mediated by carboxypeptidase E and intrinsic sorting signals.
    McGirr R, Guizzetti L, Dhanvantari S.
    J Endocrinol; 2013 May; 217(2):229-40. PubMed ID: 23418362
    [Abstract] [Full Text] [Related]

  • 4. Depletion of carboxypeptidase E, a regulated secretory pathway sorting receptor, causes misrouting and constitutive secretion of proinsulin and proenkephalin, but not chromogranin A.
    Normant E, Loh YP.
    Endocrinology; 1998 Apr; 139(4):2137-45. PubMed ID: 9529003
    [Abstract] [Full Text] [Related]

  • 5. Processing of procarboxypeptidase E into carboxypeptidase E occurs in secretory vesicles.
    Song L, Fricker L.
    J Neurochem; 1995 Jul; 65(1):444-53. PubMed ID: 7790890
    [Abstract] [Full Text] [Related]

  • 6. Induced and spontaneous mutations at Ser202 of carboxypeptidase E. Effect on enzyme expression, activity, and intracellular routing.
    Varlamov O, Leiter EH, Fricker L.
    J Biol Chem; 1996 Jun 14; 271(24):13981-6. PubMed ID: 8662840
    [Abstract] [Full Text] [Related]

  • 7. Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity.
    Naggert JK, Fricker LD, Varlamov O, Nishina PM, Rouille Y, Steiner DF, Carroll RJ, Paigen BJ, Leiter EH.
    Nat Genet; 1995 Jun 14; 10(2):135-42. PubMed ID: 7663508
    [Abstract] [Full Text] [Related]

  • 8. Molecular heterogeneity and cellular localization of carboxypeptidase H in the islets of Langerhans.
    Guest PC, Ravazzola M, Davidson HW, Orci L, Hutton JC.
    Endocrinology; 1991 Aug 14; 129(2):734-40. PubMed ID: 1855471
    [Abstract] [Full Text] [Related]

  • 9. Identification of a novel prohormone sorting signal-binding site on carboxypeptidase E, a regulated secretory pathway-sorting receptor.
    Zhang CF, Snell CR, Loh YP.
    Mol Endocrinol; 1999 Apr 14; 13(4):527-36. PubMed ID: 10194759
    [Abstract] [Full Text] [Related]

  • 10. Impaired prohormone convertases in Cpe(fat)/Cpe(fat) mice.
    Berman Y, Mzhavia N, Polonskaia A, Devi LA.
    J Biol Chem; 2001 Jan 12; 276(2):1466-73. PubMed ID: 11038363
    [Abstract] [Full Text] [Related]

  • 11. Posttranslational processing of carboxypeptidase E, a neuropeptide-processing enzyme, in AtT-20 cells and bovine pituitary secretory granules.
    Fricker LD, Devi L.
    J Neurochem; 1993 Oct 12; 61(4):1404-15. PubMed ID: 8376994
    [Abstract] [Full Text] [Related]

  • 12. Sorting of carboxypeptidase E to the regulated secretory pathway requires interaction of its transmembrane domain with lipid rafts.
    Zhang CF, Dhanvantari S, Lou H, Loh YP.
    Biochem J; 2003 Feb 01; 369(Pt 3):453-60. PubMed ID: 12403651
    [Abstract] [Full Text] [Related]

  • 13. Differential regulation and localization of carboxypeptidase D and carboxypeptidase E in human and mouse β-cells.
    Chu KY, Briggs MJ, Albrecht T, Drain PF, Johnson JD.
    Islets; 2011 Feb 01; 3(4):155-65. PubMed ID: 21628999
    [Abstract] [Full Text] [Related]

  • 14. Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpe(fat) mice.
    Cool DR, Normant E, Shen F, Chen HC, Pannell L, Zhang Y, Loh YP.
    Cell; 1997 Jan 10; 88(1):73-83. PubMed ID: 9019408
    [Abstract] [Full Text] [Related]

  • 15. Proinsulin targeting to the regulated pathway is not impaired in carboxypeptidase E-deficient Cpefat/Cpefat mice.
    Irminger JC, Verchere CB, Meyer K, Halban PA.
    J Biol Chem; 1997 Oct 31; 272(44):27532-4. PubMed ID: 9346885
    [Abstract] [Full Text] [Related]

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  • 17. Glu300 of rat carboxypeptidase E is essential for enzymatic activity but not substrate binding or routing to the regulated secretory pathway.
    Qian Y, Varlamov O, Fricker LD.
    J Biol Chem; 1999 Apr 23; 274(17):11582-6. PubMed ID: 10206965
    [Abstract] [Full Text] [Related]

  • 18. Cholecystokinin (CCK) levels are greatly reduced in the brains but not the duodenums of Cpe(fat)/Cpe(fat) mice: a regional difference in the involvement of carboxypeptidase E (Cpe) in pro-CCK processing.
    Cain BM, Wang W, Beinfeld MC.
    Endocrinology; 1997 Sep 23; 138(9):4034-7. PubMed ID: 9275097
    [Abstract] [Full Text] [Related]

  • 19. Role of carboxypeptidase E in processing of pro-islet amyloid polypeptide in {beta}-cells.
    Marzban L, Soukhatcheva G, Verchere CB.
    Endocrinology; 2005 Apr 23; 146(4):1808-17. PubMed ID: 15618358
    [Abstract] [Full Text] [Related]

  • 20. Altered neuropeptide processing in prefrontal cortex of Cpe (fat/fat) mice: implications for neuropeptide discovery.
    Lim J, Berezniuk I, Che FY, Parikh R, Biswas R, Pan H, Fricker LD.
    J Neurochem; 2006 Feb 23; 96(4):1169-81. PubMed ID: 16417576
    [Abstract] [Full Text] [Related]

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