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202 related items for PubMed ID: 12490578

  • 1. Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity.
    Chalon S, Tarkiainen J, Garreau L, Hall H, Emond P, Vercouillie J, Farde L, Dasse P, Varnas K, Besnard JC, Halldin C, Guilloteau D.
    J Pharmacol Exp Ther; 2003 Jan; 304(1):81-7. PubMed ID: 12490578
    [Abstract] [Full Text] [Related]

  • 2. N-(3-lodoprop-2E-enyl)-2beta-carbomethoxy-3beta-(3',4'-dichloro phenyl)nortropane (beta-CDIT), a tropane derivative: pharmacological characterization as a specific ligand for the dopamine transporter in the rodent brain.
    Garreau L, Emond P, Belzung C, Guilloteau D, Frangin Y, Besnard JC, Chalon S.
    J Pharmacol Exp Ther; 1997 Jul; 282(1):467-74. PubMed ID: 9223589
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and characterization of iodine-123 labeled 2beta-carbomethoxy-3beta-(4'-((Z)-2-iodoethenyl)phenyl)nortropane. A ligand for in vivo imaging of serotonin transporters by single-photon-emission tomography.
    Goodman MM, Chen P, Plisson C, Martarello L, Galt J, Votaw JR, Kilts CD, Malveaux G, Camp VM, Shi B, Ely TD, Howell L, McConathy J, Nemeroff CB.
    J Med Chem; 2003 Mar 13; 46(6):925-35. PubMed ID: 12620070
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and in vivo evaluation of halogenated N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)benzylamine derivatives as PET serotonin transporter ligands.
    Jarkas N, Voll RJ, Williams L, Votaw JR, Owens M, Goodman MM.
    J Med Chem; 2008 Jan 24; 51(2):271-81. PubMed ID: 18085744
    [Abstract] [Full Text] [Related]

  • 5. Pharmacological and genetic characterization of two selective serotonin transporter ligands: 2-[2-(dimethylaminomethylphenylthio)]-5-fluoromethylphenylamine (AFM) and 3-amino-4-[2-(dimethylaminomethyl-phenylthio)]benzonitrile (DASB).
    Li Q, Ma L, Innis RB, Seneca N, Ichise M, Huang H, Laruelle M, Murphy DL.
    J Pharmacol Exp Ther; 2004 Feb 24; 308(2):481-6. PubMed ID: 14610240
    [Abstract] [Full Text] [Related]

  • 6. Synthesis, radiosynthesis, and biological evaluation of carbon-11 and iodine-123 labeled 2beta-carbomethoxy-3beta-[4'-((Z)-2-haloethenyl)phenyl]tropanes: candidate radioligands for in vivo imaging of the serotonin transporter.
    Plisson C, McConathy J, Martarello L, Malveaux EJ, Camp VM, Williams L, Votaw JR, Goodman MM.
    J Med Chem; 2004 Feb 26; 47(5):1122-35. PubMed ID: 14971892
    [Abstract] [Full Text] [Related]

  • 7. Fluorinated diaryl sulfides as serotonin transporter ligands: synthesis, structure-activity relationship study, and in vivo evaluation of fluorine-18-labeled compounds as PET imaging agents.
    Huang Y, Bae SA, Zhu Z, Guo N, Roth BL, Laruelle M.
    J Med Chem; 2005 Apr 07; 48(7):2559-70. PubMed ID: 15801845
    [Abstract] [Full Text] [Related]

  • 8. Quantification of 11C-MADAM binding to the serotonin transporter in the human brain.
    Lundberg J, Odano I, Olsson H, Halldin C, Farde L.
    J Nucl Med; 2005 Sep 07; 46(9):1505-15. PubMed ID: 16157534
    [Abstract] [Full Text] [Related]

  • 9. 2-(2-(dimethylaminomethyl)phenoxy)-5-iodophenylamine: an improved serotonin transporter imaging agent.
    Kung HF, Newman S, Choi SR, Oya S, Hou C, Zhuang ZP, Acton PD, Plössl K, Winkler J, Kung MP.
    J Med Chem; 2004 Oct 07; 47(21):5258-64. PubMed ID: 15456270
    [Abstract] [Full Text] [Related]

  • 10. IPT: a novel iodinated ligand for the CNS dopamine transporter.
    Kung MP, Essman WD, Frederick D, Meegalla S, Goodman M, Mu M, Lucki I, Kung HF.
    Synapse; 1995 Aug 07; 20(4):316-24. PubMed ID: 7482291
    [Abstract] [Full Text] [Related]

  • 11. Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)piperidin-4-ylmethyl]amine.
    Kolhatkar RB, Ghorai SK, George C, Reith ME, Dutta AK.
    J Med Chem; 2003 May 22; 46(11):2205-15. PubMed ID: 12747792
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and characterization of EADAM: a selective radioligand for mapping the brain serotonin transporters by positron emission tomography.
    Jarkas N, McConathy J, Votaw JR, Voll RJ, Malveaux E, Camp VM, Williams L, Goodman RR, Kilts CD, Goodman MM.
    Nucl Med Biol; 2005 Jan 22; 32(1):75-86. PubMed ID: 15691664
    [Abstract] [Full Text] [Related]

  • 13. Effects of tryptophan depletion on the binding of [11C]-DASB to the serotonin transporter in baboons: response to acute serotonin deficiency.
    Milak MS, Ogden RT, Vinocur DN, Van Heertum RL, Cooper TB, Mann JJ, Parsey RV.
    Biol Psychiatry; 2005 Jan 01; 57(1):102-6. PubMed ID: 15607307
    [Abstract] [Full Text] [Related]

  • 14. Synthesis, in vitro characterization, and radiolabeling of N,N-dimethyl-2-(2'-amino-4'-substituted-phenylthio)benzylamines: potential candidates as selective serotonin transporter radioligands.
    Jarkas N, McConathy J, Voll RJ, Goodman MM.
    J Med Chem; 2005 Jun 30; 48(13):4254-65. PubMed ID: 15974579
    [Abstract] [Full Text] [Related]

  • 15. Characterization of FlipIDAM as a SERT-selective SPECT imaging agent.
    Lemoine L, Lieberman BP, Ploessl K, Zheng P, Kung HF.
    Nucl Med Biol; 2013 Oct 30; 40(7):879-86. PubMed ID: 23856117
    [Abstract] [Full Text] [Related]

  • 16. N,N-dimethyl-2-(2-amino-4-(18)F-fluorophenylthio)-benzylamine (4-(18)F-ADAM): an improved PET radioligand for serotonin transporters.
    Shiue GG, Choi SR, Fang P, Hou C, Acton PD, Cardi C, Saffer JR, Greenberg JH, Karp JS, Kung HF, Shiue CY.
    J Nucl Med; 2003 Dec 30; 44(12):1890-7. PubMed ID: 14660713
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and biological evaluation of [11C]talopram and [11C]talsupram: candidate PET ligands for the norepinephrine transporter.
    McConathy J, Owens MJ, Kilts CD, Malveaux EJ, Camp VM, Votaw JR, Nemeroff CB, Goodman MM.
    Nucl Med Biol; 2004 Aug 30; 31(6):705-18. PubMed ID: 15246361
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and in vivo evaluation of fluorine-18 and iodine-123 labeled 2beta-carbo(2-fluoroethoxy)-3beta-(4'-((Z)-2-iodoethenyl)phenyl)nortropane as a candidate serotonin transporter imaging agent.
    Plisson C, Stehouwer JS, Voll RJ, Howell L, Votaw JR, Owens MJ, Goodman MM.
    J Med Chem; 2007 Sep 20; 50(19):4553-60. PubMed ID: 17705359
    [Abstract] [Full Text] [Related]

  • 19. Studies of the biogenic amine transporters. IV. Demonstration of a multiplicity of binding sites in rat caudate membranes for the cocaine analog [125I]RTI-55.
    Rothman RB, Cadet JL, Akunne HC, Silverthorn ML, Baumann MH, Carroll FI, Rice KC, de Costa BR, Partilla JS, Wang JB.
    J Pharmacol Exp Ther; 1994 Jul 20; 270(1):296-309. PubMed ID: 8035327
    [Abstract] [Full Text] [Related]

  • 20. High affinity hydroxypiperidine analogues of 4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidine for the dopamine transporter: stereospecific interactions in vitro and in vivo.
    Ghorai SK, Cook C, Davis M, Venkataraman SK, George C, Beardsley PM, Reith ME, Dutta AK.
    J Med Chem; 2003 Mar 27; 46(7):1220-8. PubMed ID: 12646032
    [Abstract] [Full Text] [Related]

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