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Journal Abstract Search


371 related items for PubMed ID: 12492197

  • 1. Th1-mediated intestinal inflammation in Crohn's disease may be induced by activation of lamina propria lymphocytes through synergistic stimulation of interleukin-12 and interleukin-18 without T cell receptor engagement.
    Okazawa A, Kanai T, Watanabe M, Yamazaki M, Inoue N, Ikeda M, Kurimoto M, Ishii H, Hibi T.
    Am J Gastroenterol; 2002 Dec; 97(12):3108-17. PubMed ID: 12492197
    [Abstract] [Full Text] [Related]

  • 2. T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction of Th1 mediated immunopathology in Crohn's disease.
    Matsuoka K, Inoue N, Sato T, Okamoto S, Hisamatsu T, Kishi Y, Sakuraba A, Hitotsumatsu O, Ogata H, Koganei K, Fukushima T, Kanai T, Watanabe M, Ishii H, Hibi T.
    Gut; 2004 Sep; 53(9):1303-8. PubMed ID: 15306590
    [Abstract] [Full Text] [Related]

  • 3. Expression of interleukin 12 receptor (IL-12R) and IL-18R on CD4+ T cells from patients with rheumatoid arthritis.
    Aita T, Yamamura M, Kawashima M, Okamoto A, Iwahashi M, Yamana J, Makino H.
    J Rheumatol; 2004 Mar; 31(3):448-56. PubMed ID: 14994387
    [Abstract] [Full Text] [Related]

  • 4. IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production.
    Yoshimoto T, Takeda K, Tanaka T, Ohkusu K, Kashiwamura S, Okamura H, Akira S, Nakanishi K.
    J Immunol; 1998 Oct 01; 161(7):3400-7. PubMed ID: 9759857
    [Abstract] [Full Text] [Related]

  • 5. In vitro interleukin 12 activation of peripheral blood CD3(+)CD56(+) and CD3(+)CD56(-) gammadelta T cells from glioblastoma patients.
    Fujimiya Y, Suzuki Y, Katakura R, Miyagi T, Yamaguchi T, Yoshimoto T, Ebina T.
    Clin Cancer Res; 1997 Apr 01; 3(4):633-43. PubMed ID: 9815731
    [Abstract] [Full Text] [Related]

  • 6. Synergistic proliferation and activation of natural killer cells by interleukin 12 and interleukin 18.
    Lauwerys BR, Renauld JC, Houssiau FA.
    Cytokine; 1999 Nov 01; 11(11):822-30. PubMed ID: 10547269
    [Abstract] [Full Text] [Related]

  • 7. Differential capacities of CD4+, CD8+, and CD4-CD8- T cell subsets to express IL-18 receptor and produce IFN-gamma in response to IL-18.
    Tomura M, Maruo S, Mu J, Zhou XY, Ahn HJ, Hamaoka T, Okamura H, Nakanishi K, Clark S, Kurimoto M, Fujiwara H.
    J Immunol; 1998 Apr 15; 160(8):3759-65. PubMed ID: 9558078
    [Abstract] [Full Text] [Related]

  • 8. Synergistic effects of IL-7 and IL-12 on human T cell activation.
    Mehrotra PT, Grant AJ, Siegel JP.
    J Immunol; 1995 May 15; 154(10):5093-102. PubMed ID: 7730615
    [Abstract] [Full Text] [Related]

  • 9. CD4+NKG2D+ T cells in Crohn's disease mediate inflammatory and cytotoxic responses through MICA interactions.
    Allez M, Tieng V, Nakazawa A, Treton X, Pacault V, Dulphy N, Caillat-Zucman S, Paul P, Gornet JM, Douay C, Ravet S, Tamouza R, Charron D, Lémann M, Mayer L, Toubert A.
    Gastroenterology; 2007 Jun 15; 132(7):2346-58. PubMed ID: 17570210
    [Abstract] [Full Text] [Related]

  • 10. Interleukin-25 inhibits interleukin-12 production and Th1 cell-driven inflammation in the gut.
    Caruso R, Sarra M, Stolfi C, Rizzo A, Fina D, Fantini MC, Pallone F, MacDonald TT, Monteleone G.
    Gastroenterology; 2009 Jun 15; 136(7):2270-9. PubMed ID: 19505427
    [Abstract] [Full Text] [Related]

  • 11. Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease.
    Di Sabatino A, Ciccocioppo R, Cupelli F, Cinque B, Millimaggi D, Clarkson MM, Paulli M, Cifone MG, Corazza GR.
    Gut; 2006 Apr 15; 55(4):469-77. PubMed ID: 16105889
    [Abstract] [Full Text] [Related]

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  • 13. Increased expression of interleukin-12 receptor beta(2) on lamina propria mononuclear cells of patients with active Crohn's disease.
    Stallmach A, Marth T, Adrian N, Wittig BM, Ecker KW, Schilling M, Zeitz M.
    Int J Colorectal Dis; 2002 Sep 15; 17(5):303-10. PubMed ID: 12172923
    [Abstract] [Full Text] [Related]

  • 14. A soluble factor produced by lamina propria mononuclear cells is required for TNF-alpha enhancement of IFN-gamma production by T cells.
    Prehn JL, Landers CJ, Targan SR.
    J Immunol; 1999 Oct 15; 163(8):4277-83. PubMed ID: 10510366
    [Abstract] [Full Text] [Related]

  • 15. In vitro analysis of interferon gamma (IFN-gamma) and interleukin-12 (IL-12) production and their effects in ileal Crohn's disease.
    Colpaert S, Vastraelen K, Liu Z, Maerten P, Shen C, Penninckx F, Geboes K, Rutgeerts P, Ceuppens JL.
    Eur Cytokine Netw; 2002 Oct 15; 13(4):431-7. PubMed ID: 12517728
    [Abstract] [Full Text] [Related]

  • 16. Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease.
    Parronchi P, Romagnani P, Annunziato F, Sampognaro S, Becchio A, Giannarini L, Maggi E, Pupilli C, Tonelli F, Romagnani S.
    Am J Pathol; 1997 Mar 15; 150(3):823-32. PubMed ID: 9060820
    [Abstract] [Full Text] [Related]

  • 17. An early imbalance of interleukin 12 influences the adjuvant effect of mannoproteins of Cryptococcus neoformans.
    Pietrella D, Lupo P, Bistoni F, Vecchiarelli A.
    Cell Microbiol; 2004 Sep 15; 6(9):883-91. PubMed ID: 15272868
    [Abstract] [Full Text] [Related]

  • 18. Potential role for TL1A, the new TNF-family member and potent costimulator of IFN-gamma, in mucosal inflammation.
    Prehn JL, Mehdizadeh S, Landers CJ, Luo X, Cha SC, Wei P, Targan SR.
    Clin Immunol; 2004 Jul 15; 112(1):66-77. PubMed ID: 15207783
    [Abstract] [Full Text] [Related]

  • 19. A functional role of flip in conferring resistance of Crohn's disease lamina propria lymphocytes to FAS-mediated apoptosis.
    Monteleone I, Monteleone G, Fina D, Caruso R, Petruzziello C, Calabrese E, Biancone L, Pallone F.
    Gastroenterology; 2006 Feb 15; 130(2):389-97. PubMed ID: 16472594
    [Abstract] [Full Text] [Related]

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