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Journal Abstract Search

391 related items for PubMed ID: 12502360

  • 1. Hydantoin-substituted 4,6-dichloroindole-2-carboxylic acids as ligands with high affinity for the glycine binding site of the NMDA receptor.
    Jansen M, Potschka H, Brandt C, Löscher W, Dannhardt G.
    J Med Chem; 2003 Jan 02; 46(1):64-73. PubMed ID: 12502360
    [Abstract] [Full Text] [Related]

  • 2. CoMFA, synthesis, and pharmacological evaluation of (E)-3-(2-carboxy-2-arylvinyl)-4,6-dichloro-1H-indole-2-carboxylic acids: 3-[2-(3-aminophenyl)-2-carboxyvinyl]-4,6-dichloro-1H-indole-2-carboxylic acid, a potent selective glycine-site NMDA receptor antagonist.
    Baron BM, Cregge RJ, Farr RA, Friedrich D, Gross RS, Harrison BL, Janowick DA, Matthews D, McCloskey TC, Meikrantz S, Nyce PL, Vaz R, Metz WA.
    J Med Chem; 2005 Feb 24; 48(4):995-1018. PubMed ID: 15715469
    [Abstract] [Full Text] [Related]

  • 3. Tricyclic indole-2-carboxylic acids: highly in vivo active and selective antagonists for the glycine binding site of the NMDA receptor.
    Katayama S, Ae N, Kodo T, Masumoto S, Hourai S, Tamamura C, Tanaka H, Nagata R.
    J Med Chem; 2003 Feb 27; 46(5):691-701. PubMed ID: 12593650
    [Abstract] [Full Text] [Related]

  • 4. 4-substituted-3-phenylquinolin-2(1H)-ones: acidic and nonacidic glycine site N-methyl-D-aspartate antagonists with in vivo activity.
    Carling RW, Leeson PD, Moore KW, Moyes CR, Duncton M, Hudson ML, Baker R, Foster AC, Grimwood S, Kemp JA, Marshall GR, Tricklebank MD, Saywell KL.
    J Med Chem; 1997 Feb 28; 40(5):754-65. PubMed ID: 9057862
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  • 5. Structure-activity relationships of alkyl- and alkoxy-substituted 1,4-dihydroquinoxaline-2,3-diones: potent and systemically active antagonists for the glycine site of the NMDA receptor.
    Cai SX, Kher SM, Zhou ZL, Ilyin V, Espitia SA, Tran M, Hawkinson JE, Woodward RM, Weber E, Keana JF.
    J Med Chem; 1997 Feb 28; 40(5):730-8. PubMed ID: 9057859
    [Abstract] [Full Text] [Related]

  • 6. Substituted indole-2-carboxylates as in vivo potent antagonists acting as the strychnine-insensitive glycine binding site.
    Di Fabio R, Capelli AM, Conti N, Cugola A, Donati D, Feriani A, Gastaldi P, Gaviraghi G, Hewkin CT, Micheli F, Missio A, Mugnaini M, Pecunioso A, Quaglia AM, Ratti E, Rossi L, Tedesco G, Trist DG, Reggiani A.
    J Med Chem; 1997 Mar 14; 40(6):841-50. PubMed ID: 9083472
    [Abstract] [Full Text] [Related]

  • 7. [3H]MDL 105,519, a high-affinity radioligand for the N-methyl-D-aspartate receptor-associated glycine recognition site.
    Baron BM, Siegel BW, Harrison BL, Gross RS, Hawes C, Towers P.
    J Pharmacol Exp Ther; 1996 Oct 14; 279(1):62-8. PubMed ID: 8858976
    [Abstract] [Full Text] [Related]

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  • 10. Characterization of indole-2-carboxylate derivatives as antagonists of N-methyl-D-aspartate receptor activity at the associated glycine recognition site.
    Hood WF, Gray NM, Dappen MS, Watson GB, Compton RP, Cordi AA, Lanthorn TH, Monahan JB.
    J Pharmacol Exp Ther; 1992 Aug 14; 262(2):654-60. PubMed ID: 1386886
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  • 12. Glycine derivatives of imidazolones as potential ligands of glycine binding site of NMDA receptors. Part 1.
    Kieć-Kononowicz K, Karolak-Wojciechowska J, Handzlik J.
    Acta Pol Pharm; 1998 Aug 14; 55(5):381-8. PubMed ID: 9921116
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  • 14. Synthesis and potential anticonvulsant activity of new N-3-substituted 5,5-cyclopropanespirohydantoins.
    Zhu Q, Pan Y, Xu Z, Li R, Qiu G, Xu W, Ke X, Wu L, Hu X.
    Eur J Med Chem; 2009 Jan 14; 44(1):296-302. PubMed ID: 18396358
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  • 15. Synthesis of thieno[2,3-b]pyridinones acting as cytoprotectants and as inhibitors of [3H]glycine binding to the N-methyl-D-aspartate (NMDA) receptor.
    Buchstaller HP, Siebert CD, Steinmetz R, Frank I, Berger ML, Gottschlich R, Leibrock J, Krug M, Steinhilber D, Noe CR.
    J Med Chem; 2006 Feb 09; 49(3):864-71. PubMed ID: 16451052
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and biological characterization of 3-substituted-1H-indoles as ligands of GluN2B-containing N-methyl-D-aspartate receptors.
    Gitto R, De Luca L, Ferro S, Buemi MR, Russo E, De Sarro G, Costa L, Ciranna L, Prezzavento O, Arena E, Ronsisvalle S, Bruno G, Chimirri A.
    J Med Chem; 2011 Dec 22; 54(24):8702-6. PubMed ID: 22050212
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  • 18. Structure and activity studies on glycine receptor ligands. Part 5. Diphenyl imidazolin-4-one glycinamides.
    Kieć-Kononowicz K, Karolak-Wojciechowska J.
    Acta Pol Pharm; 1998 Dec 22; 55(5):389-96. PubMed ID: 9921117
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and structure-activity relationship studies for hydantoins and analogues as voltage-gated sodium channel ligands.
    Zha C, Brown GB, Brouillette WJ.
    J Med Chem; 2004 Dec 16; 47(26):6519-28. PubMed ID: 15588087
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