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138 related items for PubMed ID: 12512694

  • 1. Cerivastatin potentiates nitric oxide release and enos expression through inhibition of isoprenoids synthesis.
    Kalinowski L, Dobrucki IT, Malinski T.
    J Physiol Pharmacol; 2002 Dec; 53(4 Pt 1):585-95. PubMed ID: 12512694
    [Abstract] [Full Text] [Related]

  • 2. Isoprenoid depletion by statins antagonizes cytokine-induced down-regulation of endothelial nitric oxide expression and increases NO synthase activity in human umbilical vein endothelial cells.
    Jantzen F, Könemann S, Wolff B, Barth S, Staudt A, Kroemer HK, Dahm JB, Felix SB, Landsberger M.
    J Physiol Pharmacol; 2007 Sep; 58(3):503-14. PubMed ID: 17928646
    [Abstract] [Full Text] [Related]

  • 3. Statins blunt thrombin-induced down-regulation of endothelial nitric oxide synthase expression in human endothelial cells.
    Eto M, Rathgeb L, Cosentino F, Kozai T, Lüscher TF.
    J Cardiovasc Pharmacol; 2006 May; 47(5):663-7. PubMed ID: 16775505
    [Abstract] [Full Text] [Related]

  • 4. Increased nitric oxide bioavailability in endothelial cells contributes to the pleiotropic effect of cerivastatin.
    Kalinowski L, Dobrucki LW, Brovkovych V, Malinski T.
    Circulation; 2002 Feb 26; 105(8):933-8. PubMed ID: 11864921
    [Abstract] [Full Text] [Related]

  • 5. Differential effects of different statins on endothelin-1 gene expression and endothelial NOS phosphorylation in porcine aortic endothelial cells.
    Ohkita M, Sugii M, Ka Y, Kitamura A, Mori T, Hayashi T, Takaoka M, Matsumura Y.
    Exp Biol Med (Maywood); 2006 Jun 26; 231(6):772-6. PubMed ID: 16740997
    [Abstract] [Full Text] [Related]

  • 6. Cerivastatin suppresses lipopolysaccharide-induced ICAM-1 expression through inhibition of Rho GTPase in BAEC.
    Takeuchi S, Kawashima S, Rikitake Y, Ueyama T, Inoue N, Hirata K, Yokoyama M.
    Biochem Biophys Res Commun; 2000 Mar 05; 269(1):97-102. PubMed ID: 10694484
    [Abstract] [Full Text] [Related]

  • 7. Blockade of geranylgeranylation by rosuvastatin upregulates eNOS expression in human venous endothelial cells.
    Landsberger M, Jantzen F, Könemann S, Felix SB.
    Biochem Biophys Res Commun; 2005 Nov 04; 336(4):1005-9. PubMed ID: 16165089
    [Abstract] [Full Text] [Related]

  • 8. Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase.
    Laufs U, Liao JK.
    J Biol Chem; 1998 Sep 11; 273(37):24266-71. PubMed ID: 9727051
    [Abstract] [Full Text] [Related]

  • 9. Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells.
    Hernández-Perera O, Pérez-Sala D, Navarro-Antolín J, Sánchez-Pascuala R, Hernández G, Díaz C, Lamas S.
    J Clin Invest; 1998 Jun 15; 101(12):2711-9. PubMed ID: 9637705
    [Abstract] [Full Text] [Related]

  • 10. Endothelial nitric oxide synthase is essential for the HMG-CoA reductase inhibitor cerivastatin to promote collateral growth in response to ischemia.
    Sata M, Nishimatsu H, Suzuki E, Sugiura S, Yoshizumi M, Ouchi Y, Hirata Y, Nagai R.
    FASEB J; 2001 Nov 15; 15(13):2530-2. PubMed ID: 11641268
    [Abstract] [Full Text] [Related]

  • 11. Adverse balance of nitric oxide/peroxynitrite in the dysfunctional endothelium can be reversed by statins.
    Heeba G, Hassan MK, Khalifa M, Malinski T.
    J Cardiovasc Pharmacol; 2007 Oct 15; 50(4):391-8. PubMed ID: 18049306
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of LOX-1 by statins may relate to upregulation of eNOS.
    Mehta JL, Li DY, Chen HJ, Joseph J, Romeo F.
    Biochem Biophys Res Commun; 2001 Dec 14; 289(4):857-61. PubMed ID: 11735125
    [Abstract] [Full Text] [Related]

  • 13. Simvastatin inhibits the migration and adhesion of monocytic cells and disorganizes the cytoskeleton of activated endothelial cells.
    Pozo M, de Nicolás R, Egido J, González-Cabrero J.
    Eur J Pharmacol; 2006 Oct 24; 548(1-3):53-63. PubMed ID: 16973154
    [Abstract] [Full Text] [Related]

  • 14. The HMG-CoA reductase inhibitor cerivastatin enhances the nitric oxide bioavailability of the endothelium.
    Berkels R, Nouri SK, Taubert D, Bartels H, Roesen P, Roesen R, Klaus W.
    J Cardiovasc Pharmacol; 2003 Sep 24; 42(3):356-63. PubMed ID: 12960680
    [Abstract] [Full Text] [Related]

  • 15. Cerivastatin prevents tumor necrosis factor-alpha-induced downregulation of endothelial nitric oxide synthase: role of endothelial cytosolic proteins.
    González-Fernández F, Jiménez A, López-Blaya A, Velasco S, Arriero MM, Celdrán A, Rico L, Farré J, Casado S, López-Farré A.
    Atherosclerosis; 2001 Mar 24; 155(1):61-70. PubMed ID: 11223427
    [Abstract] [Full Text] [Related]

  • 16. Lipid-independent effects of statins on endothelial function and bioavailability of nitric oxide in hypercholesterolemic patients.
    John S, Schneider MP, Delles C, Jacobi J, Schmieder RE.
    Am Heart J; 2005 Mar 24; 149(3):473. PubMed ID: 15864218
    [Abstract] [Full Text] [Related]

  • 17. Statins inhibit secretion of metalloproteinases-1, -2, -3, and -9 from vascular smooth muscle cells and macrophages.
    Luan Z, Chase AJ, Newby AC.
    Arterioscler Thromb Vasc Biol; 2003 May 01; 23(5):769-75. PubMed ID: 12663370
    [Abstract] [Full Text] [Related]

  • 18. Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation.
    Wagner AH, Köhler T, Rückschloss U, Just I, Hecker M.
    Arterioscler Thromb Vasc Biol; 2000 Jan 01; 20(1):61-9. PubMed ID: 10634801
    [Abstract] [Full Text] [Related]

  • 19. Simvastatin inhibits C-reactive protein-induced pro-inflammatory changes in endothelial cells by decreasing mevalonate pathway products.
    Liang YJ, Shyu KG, Wang BW, Lai LP.
    Cardiology; 2008 Jan 01; 110(3):182-90. PubMed ID: 18057884
    [Abstract] [Full Text] [Related]

  • 20. Hydrogen peroxide restrains endothelium-derived nitric oxide bioactivity -- role for iron-dependent oxidative stress.
    Thomas SR, Schulz E, Keaney JF.
    Free Radic Biol Med; 2006 Aug 15; 41(4):681-8. PubMed ID: 16864001
    [Abstract] [Full Text] [Related]

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