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207 related items for PubMed ID: 12515830
1. Modulation of transforming growth factor-beta (TGF-beta) signaling by endogenous sphingolipid mediators. Sato M, Markiewicz M, Yamanaka M, Bielawska A, Mao C, Obeid LM, Hannun YA, Trojanowska M. J Biol Chem; 2003 Mar 14; 278(11):9276-82. PubMed ID: 12515830 [Abstract] [Full Text] [Related]
2. Sphingosine kinase 1 (SPHK1) is induced by transforming growth factor-beta and mediates TIMP-1 up-regulation. Yamanaka M, Shegogue D, Pei H, Bu S, Bielawska A, Bielawski J, Pettus B, Hannun YA, Obeid L, Trojanowska M. J Biol Chem; 2004 Dec 24; 279(52):53994-4001. PubMed ID: 15485866 [Abstract] [Full Text] [Related]
3. The transforming growth factor-beta/SMAD signaling pathway is present and functional in human mesangial cells. Poncelet AC, de Caestecker MP, Schnaper HW. Kidney Int; 1999 Oct 24; 56(4):1354-65. PubMed ID: 10504488 [Abstract] [Full Text] [Related]
4. Sp1 and Smad proteins cooperate to mediate transforming growth factor-beta 1-induced alpha 2(I) collagen expression in human glomerular mesangial cells. Poncelet AC, Schnaper HW. J Biol Chem; 2001 Mar 09; 276(10):6983-92. PubMed ID: 11114293 [Abstract] [Full Text] [Related]
5. Transforming growth factor (TGF)-beta-activated kinase 1 mimics and mediates TGF-beta-induced stimulation of type II collagen synthesis in chondrocytes independent of Col2a1 transcription and Smad3 signaling. Qiao B, Padilla SR, Benya PD. J Biol Chem; 2005 Apr 29; 280(17):17562-71. PubMed ID: 15743758 [Abstract] [Full Text] [Related]
6. The tumor suppressor p53 abrogates Smad-dependent collagen gene induction in mesenchymal cells. Ghosh AK, Bhattacharyya S, Varga J. J Biol Chem; 2004 Nov 12; 279(46):47455-63. PubMed ID: 15345715 [Abstract] [Full Text] [Related]
7. The phosphatidylinositol 3-kinase/Akt pathway enhances Smad3-stimulated mesangial cell collagen I expression in response to transforming growth factor-beta1. Runyan CE, Schnaper HW, Poncelet AC. J Biol Chem; 2004 Jan 23; 279(4):2632-9. PubMed ID: 14610066 [Abstract] [Full Text] [Related]
8. Interferon-gamma interferes with transforming growth factor-beta signaling through direct interaction of YB-1 with Smad3. Higashi K, Inagaki Y, Fujimori K, Nakao A, Kaneko H, Nakatsuka I. J Biol Chem; 2003 Oct 31; 278(44):43470-9. PubMed ID: 12917425 [Abstract] [Full Text] [Related]
9. Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators. Ghosh AK, Yuan W, Mori Y, Varga J. Oncogene; 2000 Jul 20; 19(31):3546-55. PubMed ID: 10918613 [Abstract] [Full Text] [Related]
10. Phosphatidylinositol 3-kinase is involved in alpha2(I) collagen gene expression in normal and scleroderma fibroblasts. Asano Y, Ihn H, Yamane K, Jinnin M, Mimura Y, Tamaki K. J Immunol; 2004 Jun 01; 172(11):7123-35. PubMed ID: 15153536 [Abstract] [Full Text] [Related]
11. Interaction of smad3 with a proximal smad-binding element of the human alpha2(I) procollagen gene promoter required for transcriptional activation by TGF-beta. Chen SJ, Yuan W, Lo S, Trojanowska M, Varga J. J Cell Physiol; 2000 Jun 01; 183(3):381-92. PubMed ID: 10797313 [Abstract] [Full Text] [Related]
12. Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3. Yuan W, Varga J. J Biol Chem; 2001 Oct 19; 276(42):38502-10. PubMed ID: 11502752 [Abstract] [Full Text] [Related]
13. Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2. Song K, Cornelius SC, Reiss M, Danielpour D. J Biol Chem; 2003 Oct 03; 278(40):38342-51. PubMed ID: 12876289 [Abstract] [Full Text] [Related]
14. Serine-204 in the linker region of Smad3 mediates the collagen-I response to TGF-β in a cell phenotype-specific manner. Browne JA, Liu X, Schnaper HW, Hayashida T. Exp Cell Res; 2013 Nov 15; 319(19):2928-37. PubMed ID: 24080014 [Abstract] [Full Text] [Related]
15. Synergistic cooperation between Sp1 and Smad3/Smad4 mediates transforming growth factor beta1 stimulation of alpha 2(I)-collagen (COL1A2) transcription. Zhang W, Ou J, Inagaki Y, Greenwel P, Ramirez F. J Biol Chem; 2000 Dec 15; 275(50):39237-45. PubMed ID: 11007770 [Abstract] [Full Text] [Related]
16. Stimulation of type I collagen transcription in human skin fibroblasts by TGF-beta: involvement of Smad 3. Chen SJ, Yuan W, Mori Y, Levenson A, Trojanowska M, Varga J. J Invest Dermatol; 1999 Jan 15; 112(1):49-57. PubMed ID: 9886263 [Abstract] [Full Text] [Related]