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Journal Abstract Search

112 related items for PubMed ID: 12519694

  • 1. Studies on the inhibition of human cytochromes P450 by selenocysteine Se-conjugates.
    Venhorst J, Rooseboom M, Vermeulen NP, Commandeur JN.
    Xenobiotica; 2003 Jan; 33(1):57-72. PubMed ID: 12519694
    [Abstract] [Full Text] [Related]

  • 2. Induction of glutathione-S-transferase mRNA levels by chemopreventive selenocysteine Se-conjugates.
    't Hoen PA, Rooseboom M, Bijsterbosch MK, van Berkel TJ, Vermeulen NP, Commandeur JN.
    Biochem Pharmacol; 2002 May 15; 63(10):1843-9. PubMed ID: 12034368
    [Abstract] [Full Text] [Related]

  • 3. Comparative study on the bioactivation mechanisms and cytotoxicity of Te-phenyl-L-tellurocysteine, Se-phenyl-L-selenocysteine, and S-phenyl-L-cysteine.
    Rooseboom M, Vermeulen NP, Durgut F, Commandeur JN.
    Chem Res Toxicol; 2002 Dec 15; 15(12):1610-8. PubMed ID: 12482244
    [Abstract] [Full Text] [Related]

  • 4. Selenoxidation by flavin-containing monooxygenases as a novel pathway for beta-elimination of selenocysteine Se-conjugates.
    Rooseboom M, Commandeur JN, Floor GC, Rettie AE, Vermeulen NP.
    Chem Res Toxicol; 2001 Jan 15; 14(1):127-34. PubMed ID: 11170516
    [Abstract] [Full Text] [Related]

  • 5. Bioactivation of chemopreventive selenocysteine Se-conjugates and related amino acids by amino acid oxidases novel route of metabolism of selenoamino acids.
    Rooseboom M, Vermeulen NP, van Hemert N, Commandeur JN.
    Chem Res Toxicol; 2001 Aug 15; 14(8):996-1005. PubMed ID: 11511173
    [Abstract] [Full Text] [Related]

  • 6. Tissue distribution of cytosolic beta-elimination reactions of selenocysteine Se-conjugates in rat and human.
    Rooseboom M, Vermeulen NP, Groot EJ, Commandeur JN.
    Chem Biol Interact; 2002 Aug 15; 140(3):243-64. PubMed ID: 12204580
    [Abstract] [Full Text] [Related]

  • 7. Comparative cytotoxicity of 14 novel selenocysteine se-conjugates in rat renal proximal tubular cells.
    Andreadou I, van de Water B, Commandeur JN, Nagelkerke FJ, Vermeulen NP.
    Toxicol Appl Pharmacol; 1996 Nov 15; 141(1):278-87. PubMed ID: 8917701
    [Abstract] [Full Text] [Related]

  • 8. Beta-lyase-dependent attenuation of cisplatin-mediated toxicity by selenocysteine Se-conjugates in renal tubular cell lines.
    Rooseboom M, Schaaf G, Commandeur JN, Vermeulen NP, Fink-Gremmels J.
    J Pharmacol Exp Ther; 2002 Jun 15; 301(3):884-92. PubMed ID: 12023515
    [Abstract] [Full Text] [Related]

  • 9. Synthesis of novel Se-substituted selenocysteine derivatives as potential kidney selective prodrugs of biologically active selenol compounds: evaluation of kinetics of beta-elimination reactions in rat renal cytosol.
    Andreadou I, Menge WM, Commandeur JN, Worthington EA, Vermeulen NP.
    J Med Chem; 1996 May 10; 39(10):2040-6. PubMed ID: 8642562
    [Abstract] [Full Text] [Related]

  • 10. Assessment of drug-drug interaction for silymarin.
    Doehmer J, Tewes B, Klein KU, Gritzko K, Muschick H, Mengs U.
    Toxicol In Vitro; 2008 Apr 10; 22(3):610-7. PubMed ID: 18249085
    [Abstract] [Full Text] [Related]

  • 11. Thiol-targeted introduction of selenocysteine to polypeptides for synthesis of glutathione peroxidase mimics.
    Haratake M, Sakano T, Fuchigami T, Nakayama M.
    Metallomics; 2011 Jul 10; 3(7):702-9. PubMed ID: 21365111
    [Abstract] [Full Text] [Related]

  • 12. Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes.
    Yamazaki H, Shimada T.
    Xenobiotica; 1999 Mar 10; 29(3):231-41. PubMed ID: 10219964
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of rat liver cytochrome P450 isozymes by isothiocyanates and their conjugates: a structure-activity relationship study.
    Conaway CC, Jiao D, Chung FL.
    Carcinogenesis; 1996 Nov 10; 17(11):2423-7. PubMed ID: 8968058
    [Abstract] [Full Text] [Related]

  • 14. Interindividual variation in relative CYP1A2/3A4 phenotype influences susceptibility of clozapine oxidation to cytochrome P450-specific inhibition in human hepatic microsomes.
    Zhang WV, D'Esposito F, Edwards RJ, Ramzan I, Murray M.
    Drug Metab Dispos; 2008 Dec 10; 36(12):2547-55. PubMed ID: 18809730
    [Abstract] [Full Text] [Related]

  • 15. In vitro metabolism and drug interaction potential of a new highly potent anti-cytomegalovirus molecule, CMV423 (2-chloro 3-pyridine 3-yl 5,6,7,8-tetrahydroindolizine I-carboxamide).
    Bournique B, Lambert N, Boukaiba R, Martinet M.
    Br J Clin Pharmacol; 2001 Jul 10; 52(1):53-63. PubMed ID: 11453890
    [Abstract] [Full Text] [Related]

  • 16. Further assessment of 17alpha-ethinyl estradiol as an inhibitor of different human cytochrome P450 forms in vitro.
    Chang SY, Chen C, Yang Z, Rodrigues AD.
    Drug Metab Dispos; 2009 Aug 10; 37(8):1667-75. PubMed ID: 19454483
    [Abstract] [Full Text] [Related]

  • 17. Evaluation of the kinetics of beta-elimination reactions of selenocysteine Se-conjugates in human renal cytosol: possible implications for the use as kidney selective prodrugs.
    Rooseboom M, Vermeulen NP, Andreadou I, Commandeur JN.
    J Pharmacol Exp Ther; 2000 Aug 10; 294(2):762-9. PubMed ID: 10900258
    [Abstract] [Full Text] [Related]

  • 18. Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man.
    Venkatakrishnan K, von Moltke LL, Duan SX, Fleishaker JC, Shader RI, Greenblatt DJ.
    J Pharm Pharmacol; 1998 Mar 10; 50(3):265-74. PubMed ID: 9600717
    [Abstract] [Full Text] [Related]

  • 19. Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver.
    Oetari S, Sudibyo M, Commandeur JN, Samhoedi R, Vermeulen NP.
    Biochem Pharmacol; 1996 Jan 12; 51(1):39-45. PubMed ID: 8534266
    [Abstract] [Full Text] [Related]

  • 20. Effects of dietary selenite, selenocystine and selenomethionine on selenocysteine lyase and glutathione peroxidase activities and on selenium levels in rat tissues.
    Deagen JT, Butler JA, Beilstein MA, Whanger PD.
    J Nutr; 1987 Jan 12; 117(1):91-8. PubMed ID: 2950214
    [Abstract] [Full Text] [Related]

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