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685 related items for PubMed ID: 12520089

  • 1. Selective inhibition of FLICE-like inhibitory protein expression with small interfering RNA oligonucleotides is sufficient to sensitize tumor cells for TRAIL-induced apoptosis.
    Siegmund D, Hadwiger P, Pfizenmaier K, Vornlocher HP, Wajant H.
    Mol Med; 2002 Nov; 8(11):725-32. PubMed ID: 12520089
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  • 4. Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression.
    Grotzer MA, Eggert A, Zuzak TJ, Janss AJ, Marwaha S, Wiewrodt BR, Ikegaki N, Brodeur GM, Phillips PC.
    Oncogene; 2000 Sep 21; 19(40):4604-10. PubMed ID: 11030149
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  • 5. Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis.
    Chawla-Sarkar M, Bae SI, Reu FJ, Jacobs BS, Lindner DJ, Borden EC.
    Cell Death Differ; 2004 Aug 21; 11(8):915-23. PubMed ID: 15118763
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  • 6. Intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human multiple myeloma cells.
    Mitsiades N, Mitsiades CS, Poulaki V, Anderson KC, Treon SP.
    Blood; 2002 Mar 15; 99(6):2162-71. PubMed ID: 11877293
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  • 7. Resistance of human melanoma cells against the death ligand TRAIL is reversed by ultraviolet-B radiation via downregulation of FLIP.
    Zeise E, Weichenthal M, Schwarz T, Kulms D.
    J Invest Dermatol; 2004 Oct 15; 123(4):746-54. PubMed ID: 15373780
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  • 8. Ewing's sarcoma family tumors are sensitive to tumor necrosis factor-related apoptosis-inducing ligand and express death receptor 4 and death receptor 5.
    Mitsiades N, Poulaki V, Mitsiades C, Tsokos M.
    Cancer Res; 2001 Mar 15; 61(6):2704-12. PubMed ID: 11289151
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  • 9. Chemotherapeutic agents sensitize sarcoma cell lines to tumor necrosis factor-related apoptosis-inducing ligand-induced caspase-8 activation, apoptosis and loss of mitochondrial membrane potential.
    Hotta T, Suzuki H, Nagai S, Yamamoto K, Imakiire A, Takada E, Itoh M, Mizuguchi J.
    J Orthop Res; 2003 Sep 15; 21(5):949-57. PubMed ID: 12919886
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  • 11. Differential induction of apoptosis by tumor necrosis factor-related apoptosis-inducing ligand in human ovarian carcinoma cells.
    Lane D, Cartier A, L'Espérance S, Côté M, Rancourt C, Piché A.
    Gynecol Oncol; 2004 Jun 15; 93(3):594-604. PubMed ID: 15196850
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  • 12. Persistent c-FLIP(L) expression is necessary and sufficient to maintain resistance to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in prostate cancer.
    Zhang X, Jin TG, Yang H, DeWolf WC, Khosravi-Far R, Olumi AF.
    Cancer Res; 2004 Oct 01; 64(19):7086-91. PubMed ID: 15466204
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  • 13. An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis.
    Kim Y, Suh N, Sporn M, Reed JC.
    J Biol Chem; 2002 Jun 21; 277(25):22320-9. PubMed ID: 11940602
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  • 14. Cotreatment with histone deacetylase inhibitor LAQ824 enhances Apo-2L/tumor necrosis factor-related apoptosis inducing ligand-induced death inducing signaling complex activity and apoptosis of human acute leukemia cells.
    Guo F, Sigua C, Tao J, Bali P, George P, Li Y, Wittmann S, Moscinski L, Atadja P, Bhalla K.
    Cancer Res; 2004 Apr 01; 64(7):2580-9. PubMed ID: 15059915
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  • 15. Regulation of tumor necrosis factor-related apoptosis-inducing ligand sensitivity in primary and transformed human keratinocytes.
    Leverkus M, Neumann M, Mengling T, Rauch CT, Bröcker EB, Krammer PH, Walczak H.
    Cancer Res; 2000 Feb 01; 60(3):553-9. PubMed ID: 10676636
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  • 16. Doxorubicin pretreatment sensitizes prostate cancer cell lines to TRAIL induced apoptosis which correlates with the loss of c-FLIP expression.
    Kelly MM, Hoel BD, Voelkel-Johnson C.
    Cancer Biol Ther; 2002 Feb 01; 1(5):520-7. PubMed ID: 12496481
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  • 17. Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity.
    Ricci MS, Jin Z, Dews M, Yu D, Thomas-Tikhonenko A, Dicker DT, El-Deiry WS.
    Mol Cell Biol; 2004 Oct 01; 24(19):8541-55. PubMed ID: 15367674
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  • 18. Chemotherapeutic agents sensitize osteogenic sarcoma cells, but not normal human bone cells, to Apo2L/TRAIL-induced apoptosis.
    Evdokiou A, Bouralexis S, Atkins GJ, Chai F, Hay S, Clayer M, Findlay DM.
    Int J Cancer; 2002 Jun 01; 99(4):491-504. PubMed ID: 11992538
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  • 19. Sensitivity of Ewing's sarcoma to TRAIL-induced apoptosis.
    Kontny HU, Hämmerle K, Klein R, Shayan P, Mackall CL, Niemeyer CM.
    Cell Death Differ; 2001 May 01; 8(5):506-14. PubMed ID: 11423911
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  • 20. Role of antiapoptotic proteins in tumor necrosis factor-related apoptosis-inducing ligand and cisplatin-augmented apoptosis.
    Kim JH, Ajaz M, Lokshin A, Lee YJ.
    Clin Cancer Res; 2003 Aug 01; 9(8):3134-41. PubMed ID: 12912965
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