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145 related items for PubMed ID: 12525479

  • 1. Role of the Ca2+/phosphatidylserine binding region of the C2 domain in the translocation of protein kinase Calpha to the plasma membrane.
    Bolsover SR, Gomez-Fernandez JC, Corbalan-Garcia S.
    J Biol Chem; 2003 Mar 21; 278(12):10282-90. PubMed ID: 12525479
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  • 7. Identification of the phosphatidylserine binding site in the C2 domain that is important for PKC alpha activation and in vivo cell localization.
    Conesa-Zamora P, Lopez-Andreo MJ, Gómez-Fernández JC, Corbalán-García S.
    Biochemistry; 2001 Nov 20; 40(46):13898-905. PubMed ID: 11705379
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  • 8. Membrane binding kinetics of protein kinase C betaII mediated by the C2 domain.
    Nalefski EA, Newton AC.
    Biochemistry; 2001 Nov 06; 40(44):13216-29. PubMed ID: 11683630
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  • 9. Differential roles of phosphatidylserine, PtdIns(4,5)P2, and PtdIns(3,4,5)P3 in plasma membrane targeting of C2 domains. Molecular dynamics simulation, membrane binding, and cell translocation studies of the PKCalpha C2 domain.
    Manna D, Bhardwaj N, Vora MS, Stahelin RV, Lu H, Cho W.
    J Biol Chem; 2008 Sep 19; 283(38):26047-58. PubMed ID: 18621733
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  • 10. The molecular basis of differential subcellular localization of C2 domains of protein kinase C-alpha and group IVa cytosolic phospholipase A2.
    Stahelin RV, Rafter JD, Das S, Cho W.
    J Biol Chem; 2003 Apr 04; 278(14):12452-60. PubMed ID: 12531893
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  • 11. The C2 domain of protein kinase calpha is directly involved in the diacylglycerol-dependent binding of the C1 domain to the membrane.
    Conesa-Zamora P, Gómez-Fernández JC, Corbalán-García S.
    Biochim Biophys Acta; 2000 Sep 27; 1487(2-3):246-54. PubMed ID: 11018476
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  • 12. Electrostatic and hydrophobic interactions differentially tune membrane binding kinetics of the C2 domain of protein kinase Cα.
    Scott AM, Antal CE, Newton AC.
    J Biol Chem; 2013 Jun 07; 288(23):16905-16915. PubMed ID: 23589289
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  • 13. Interplay of C1 and C2 domains of protein kinase C-alpha in its membrane binding and activation.
    Medkova M, Cho W.
    J Biol Chem; 1999 Jul 09; 274(28):19852-61. PubMed ID: 10391930
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  • 14. The origin of C1A-C2 interdomain interactions in protein kinase Calpha.
    Stahelin RV, Wang J, Blatner NR, Rafter JD, Murray D, Cho W.
    J Biol Chem; 2005 Oct 28; 280(43):36452-63. PubMed ID: 16079140
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  • 15. Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity.
    Corbin JA, Evans JH, Landgraf KE, Falke JJ.
    Biochemistry; 2007 Apr 10; 46(14):4322-36. PubMed ID: 17367165
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  • 16. Structure of the C2 domain from novel protein kinase Cepsilon. A membrane binding model for Ca(2+)-independent C2 domains.
    Ochoa WF, Garcia-Garcia J, Fita I, Corbalan-Garcia S, Verdaguer N, Gomez-Fernandez JC.
    J Mol Biol; 2001 Aug 24; 311(4):837-49. PubMed ID: 11518534
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  • 17. Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cdelta.
    Stahelin RV, Digman MA, Medkova M, Ananthanarayanan B, Rafter JD, Melowic HR, Cho W.
    J Biol Chem; 2004 Jul 09; 279(28):29501-12. PubMed ID: 15105418
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  • 18. C2 domains of protein kinase C isoforms alpha, beta, and gamma: activation parameters and calcium stoichiometries of the membrane-bound state.
    Kohout SC, Corbalán-García S, Torrecillas A, Goméz-Fernandéz JC, Falke JJ.
    Biochemistry; 2002 Sep 24; 41(38):11411-24. PubMed ID: 12234184
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  • 19. The C1 and C2 domains of protein kinase C are independent membrane targeting modules, with specificity for phosphatidylserine conferred by the C1 domain.
    Johnson JE, Giorgione J, Newton AC.
    Biochemistry; 2000 Sep 19; 39(37):11360-9. PubMed ID: 10985781
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  • 20. Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain.
    Evans JH, Murray D, Leslie CC, Falke JJ.
    Mol Biol Cell; 2006 Jan 19; 17(1):56-66. PubMed ID: 16236797
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