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Journal Abstract Search

214 related items for PubMed ID: 12529174

  • 1. Protein-protein interactions involved in the recognition of p27 by E3 ubiquitin ligase.
    Xu K, Belunis C, Chu W, Weber D, Podlaski F, Huang KS, Reed SI, Vassilev LT.
    Biochem J; 2003 May 01; 371(Pt 3):957-64. PubMed ID: 12529174
    [Abstract] [Full Text] [Related]

  • 2. Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase.
    Hao B, Zheng N, Schulman BA, Wu G, Miller JJ, Pagano M, Pavletich NP.
    Mol Cell; 2005 Oct 07; 20(1):9-19. PubMed ID: 16209941
    [Abstract] [Full Text] [Related]

  • 3. The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27.
    Ganoth D, Bornstein G, Ko TK, Larsen B, Tyers M, Pagano M, Hershko A.
    Nat Cell Biol; 2001 Mar 07; 3(3):321-4. PubMed ID: 11231585
    [Abstract] [Full Text] [Related]

  • 4. Three different binding sites of Cks1 are required for p27-ubiquitin ligation.
    Sitry D, Seeliger MA, Ko TK, Ganoth D, Breward SE, Itzhaki LS, Pagano M, Hershko A.
    J Biol Chem; 2002 Nov 01; 277(44):42233-40. PubMed ID: 12140288
    [Abstract] [Full Text] [Related]

  • 5. PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2).
    Mamillapalli R, Gavrilova N, Mihaylova VT, Tsvetkov LM, Wu H, Zhang H, Sun H.
    Curr Biol; 2001 Feb 20; 11(4):263-7. PubMed ID: 11250155
    [Abstract] [Full Text] [Related]

  • 6. A negatively charged amino acid in Skp2 is required for Skp2-Cks1 interaction and ubiquitination of p27Kip1.
    Wang W, Ungermannova D, Chen L, Liu X.
    J Biol Chem; 2003 Aug 22; 278(34):32390-6. PubMed ID: 12813041
    [Abstract] [Full Text] [Related]

  • 7. High-throughput screening for inhibitors of the Cks1-Skp2 interaction.
    Huang KS, Vassilev LT.
    Methods Enzymol; 2005 Aug 22; 399():717-28. PubMed ID: 16338391
    [Abstract] [Full Text] [Related]

  • 8. Substrate recognition and ubiquitination of SCFSkp2/Cks1 ubiquitin-protein isopeptide ligase.
    Xu S, Abbasian M, Patel P, Jensen-Pergakes K, Lombardo CR, Cathers BE, Xie W, Mercurio F, Pagano M, Giegel D, Cox S.
    J Biol Chem; 2007 May 25; 282(21):15462-70. PubMed ID: 17409098
    [Abstract] [Full Text] [Related]

  • 9. Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1).
    Morimoto M, Nishida T, Honda R, Yasuda H.
    Biochem Biophys Res Commun; 2000 Apr 21; 270(3):1093-6. PubMed ID: 10772955
    [Abstract] [Full Text] [Related]

  • 10. CD28 costimulation mediates transcription of SKP2 and CKS1, the substrate recognition components of SCFSkp2 ubiquitin ligase that leads p27kip1 to degradation.
    Appleman LJ, Chernova I, Li L, Boussiotis VA.
    Cell Cycle; 2006 Sep 21; 5(18):2123-9. PubMed ID: 16969077
    [Abstract] [Full Text] [Related]

  • 11. Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancer.
    Pavlides SC, Huang KT, Reid DA, Wu L, Blank SV, Mittal K, Guo L, Rothenberg E, Rueda B, Cardozo T, Gold LI.
    Endocrinology; 2013 Nov 21; 154(11):4030-45. PubMed ID: 24035998
    [Abstract] [Full Text] [Related]

  • 12. Ubiquitination of p27Kip1 requires physical interaction with cyclin E and probable phosphate recognition by SKP2.
    Ungermannova D, Gao Y, Liu X.
    J Biol Chem; 2005 Aug 26; 280(34):30301-9. PubMed ID: 15980415
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of F-Box protein p45(SKP2) expression and stabilization of cyclin-dependent kinase inhibitor p27(KIP1) in vitamin D analog-treated cancer cells.
    Lin R, Wang TT, Miller WH, White JH.
    Endocrinology; 2003 Mar 26; 144(3):749-53. PubMed ID: 12586749
    [Abstract] [Full Text] [Related]

  • 14. High-throughput screening AlphaScreen assay for identification of small-molecule inhibitors of ubiquitin E3 ligase SCFSkp2-Cks1.
    Ungermannova D, Lee J, Zhang G, Dallmann HG, McHenry CS, Liu X.
    J Biomol Screen; 2013 Sep 26; 18(8):910-20. PubMed ID: 23589337
    [Abstract] [Full Text] [Related]

  • 15. Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase.
    Bashir T, Dorrello NV, Amador V, Guardavaccaro D, Pagano M.
    Nature; 2004 Mar 11; 428(6979):190-3. PubMed ID: 15014502
    [Abstract] [Full Text] [Related]

  • 16. Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication.
    Nakayama K, Nagahama H, Minamishima YA, Matsumoto M, Nakamichi I, Kitagawa K, Shirane M, Tsunematsu R, Tsukiyama T, Ishida N, Kitagawa M, Nakayama K, Hatakeyama S.
    EMBO J; 2000 May 02; 19(9):2069-81. PubMed ID: 10790373
    [Abstract] [Full Text] [Related]

  • 17. Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway.
    Lisztwan J, Marti A, Sutterlüty H, Gstaiger M, Wirbelauer C, Krek W.
    EMBO J; 1998 Jan 15; 17(2):368-83. PubMed ID: 9430629
    [Abstract] [Full Text] [Related]

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  • 20. Estrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer.
    Huang KT, Pavlides SC, Lecanda J, Blank SV, Mittal KR, Gold LI.
    PLoS One; 2012 Jan 15; 7(9):e46072. PubMed ID: 23029392
    [Abstract] [Full Text] [Related]

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